Publications by authors named "Roger D Pechous"

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plasminogen activator protease is regulated by the PhoP/PhoQ two-component system.
Kenneth T Appell, Wanfeng Guo, Madeleine Scott, Jon S Blevins, Roger D Pechous

J Bacteriol· December 2025

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BipA is a novel regulator of pesticin and a type 6 secretion system.
Madeleine G Scott, Wanfeng Guo, Jon S Blevins, Kenneth T Appell, Roger D Pechous

Infect Immun· September 2025

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Yersinia pestis and pneumonic plague: Insight into how a lethal pathogen interfaces with innate immune populations in the lung to cause severe disease.
Gopinath Venugopal, Roger D Pechous

Cell Immunol· September 2024

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An human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy.
Roger D Pechous, Priyangi A Malaviarachchi, Srijon K Banerjee, Stephanie D Byrum, Duah H Alkam

J Virol· July 2024

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SARS-CoV-2 Infection Causes Heightened Disease Severity and Mortality in a Mouse Model of Down Syndrome.
Roger D Pechous, Priyangi A Malaviarachchi, Zhuo Xing, Avrium Douglas, Samantha D Crane

Biomedicines· February 2024

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Pulmonary Expression of Interleukin-17 Contributes to Neutrophil Infiltration into the Lungs during Pneumonic Plague.
Hayley M Theriot, Priyangi A Malaviarachchi, Madeleine G Scott, Kenneth T Appell, Srijon K Banerjee, Roger D Pechous

Infect Immun· July 2023

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An human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy.
Roger D Pechous, Priyangi A Malaviarachchi, Srijon K Banerjee, Stephanie D Byrum, Duah H Alkam

bioRxiv· April 2023

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Treatment with Fluticasone Propionate Increases Antibiotic Efficacy during Treatment of Late-Stage Primary Pneumonic Plague.
Samantha D Crane, Srijon K Banerjee, Roger D Pechous

Antimicrob Agents Chemother· January 2022

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Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets.
Magen E Francis, Brian Richardson, Una Goncin, Mara McNeil, Melissa Rioux, Roger D Pechous

Sci Rep· July 2021

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The Yersinia pestis GTPase BipA Promotes Pathogenesis of Primary Pneumonic Plague.
Samantha D Crane, Srijon K Banerjee, Kara R Eichelberger, Richard C Kurten, William E Goldman, Roger D Pechous

Infect Immun· January 2021

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Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets.
Magen E Francis, Brian Richardson, Mara McNeil, Melissa Rioux, Mary K Foley, Roger D Pechous

bioRxiv· January 2021

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A Dual Role for the Plasminogen Activator Protease During the Preinflammatory Phase of Primary Pneumonic Plague.
Srijon K Banerjee, Samantha D Crane, Roger D Pechous

J Infect Dis· July 2020

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Intranasal Inoculation of Mice with Yersinia pestis and Processing of Pulmonary Tissue for Analysis.
Roger D Pechous

Methods Mol Biol· March 2020

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Modeling Pneumonic Plague in Human Precision-Cut Lung Slices Highlights a Role for the Plasminogen Activator Protease in Facilitating Type 3 Secretion.
Srijon K Banerjee, Samantha D Huckuntod, Shalynn D Mills, Richard C Kurten, Roger D Pechous

Infect Immun· August 2019

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With Friends Like These: The Complex Role of Neutrophils in the Progression of Severe Pneumonia.
Roger D Pechous

Front Cell Infect Microbiol· December 2017

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Pneumonic Plague: The Darker Side of Yersinia pestis.
Roger D Pechous, Vijay Sivaraman, Nikolas M Stasulli, William E Goldman

Trends Microbiol· March 2016

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Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague.
Nikolas M Stasulli, Kara R Eichelberger, Paul A Price, Roger D Pechous, Stephanie A Montgomery

mBio· October 2015

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Illuminating Targets of Bacterial Secretion.
Roger D Pechous, William E Goldman

PLoS Pathog· August 2015

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Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague.
Vijay Sivaraman, Roger D Pechous, Nikolas M Stasulli, Kara R Eichelberger, Edward A Miao

PLoS Pathog· March 2015

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In vivo transcriptional profiling of Yersinia pestis reveals a novel bacterial mediator of pulmonary inflammation.
Roger D Pechous, Christopher A Broberg, Nikolas M Stasulli, Virginia L Miller, William E Goldman

mBio· February 2015

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Early host cell targets of Yersinia pestis during primary pneumonic plague.
Roger D Pechous, Vijay Sivaraman, Paul A Price, Nikolas M Stasulli, William E Goldman

PLoS Pathog· May 2014

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Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.
Roger D Pechous, Travis R McCarthy, Thomas C Zahrt

Microbiol Mol Biol Rev· December 2009

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A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge.
Roger D Pechous, Travis R McCarthy, Nrusingh P Mohapatra, Shilpa Soni, Renee M Penoske

PLoS One· June 2008

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Attenuation and protective efficacy of an O-antigen-deficient mutant of Francisella tularensis LVS.
Jiaxin Li, Cheryl Ryder, Manas Mandal, Farzana Ahmed, Parastoo Azadi, Roger D Pechous

Microbiology (Reading)· September 2007

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