Publications by authors named "Roger Dinallo"

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Impact of gut permeability on estimation of oral bioavailability for chemicals in commerce and the environment.
Gregory S Honda, Elaina M Kenyon, Sarah Davidson-Fritz, Roger Dinallo, Hisham El Masri

ALTEX· April 2025

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Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.
John F Wambaugh, Barbara A Wetmore, Caroline L Ring, Chantel I Nicolas, Robert G Pearce, Roger Dinallo

Toxicol Sci· December 2019

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Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.
Hossein Razavi, Doris Riether, Christian Harcken, Jörg Bentzien, Roger M Dinallo

Bioorg Med Chem Lett· April 2014

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G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism.
Ryan M Fryer, Khing Jow Ng, Suzanne G Nodop Mazurek, Lori Patnaude, Donna J Skow, Roger M Dinallo

J Pharmacol Exp Ther· March 2014

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Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.
Christian Harcken, Doris Riether, Daniel Kuzmich, Pingrong Liu, Raj Betageri, Roger Dinallo

J Med Chem· February 2014

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The clinically-tested S1P receptor agonists, FTY720 and BAF312, demonstrate subtype-specific bradycardia (S1P₁) and hypertension (S1P₃) in rat.
Ryan M Fryer, Akalushi Muthukumarana, Paul C Harrison, Suzanne Nodop Mazurek, Rong Rhonda Chen, Roger M Dinallo

PLoS One· July 2013

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Strategic integration of in vivo cardiovascular models during lead optimization: predictive value of 4 models independent of species, route of administration, and influence of anesthesia.
Ryan M Fryer, Paul C Harrison, Akalushi Muthukumarana, Suzanne G Nodop Mazurek, Khing Jow Ng, Roger M Dinallo

J Cardiovasc Pharmacol· April 2012

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Mitigation of off-target adrenergic binding and effects on cardiovascular function in the discovery of novel ribosomal S6 kinase 2 inhibitors.
Ryan M Fryer, Akalushi Muthukumarana, Rong Rhonda Chen, James D Smith, Suzanne Nodop Mazurek, Roger M Dinallo

J Pharmacol Exp Ther· March 2012

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Non-steroidal dissociated glucocorticoid agonists: indoles as A-ring mimetics and function-regulating pharmacophores.
Raj Betageri, Thomas Gilmore, Daniel Kuzmich, Thomas M Kirrane, Jörg Bentzien, Roger Dinallo

Bioorg Med Chem Lett· November 2011

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Nonsteroidal dissociated glucocorticoid agonists containing azaindoles as steroid A-ring mimetics.
Doris Riether, Christian Harcken, Hossein Razavi, Daniel Kuzmich, Thomas Gilmore, Roger Dinallo

J Med Chem· September 2010

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