Publications by authors named "Roger J Davis"

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JNK3 regulates β cell responses to incretins in human islets and mouse models.
Ruy A Louzada, Marel Gonzalez Medina, Valentina Pita-Grisanti, Jessica Bouviere, Amanda F Neves, Roger J Davis

J Clin Invest· January 2026

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Differential Protective Roles of c-Jun N-terminal Kinase-2 in Nonparenchymal Liver Cells and Hepatocytes During Cholestasis.
Mohamed Ramadan Mohamed, Gang Zhao, Ines Volkert, Antonio Molinaro, Carolin V Schneider, Roger J Davis

Cell Mol Gastroenterol Hepatol· October 2025

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JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism.
Iara Fernández-González, Oscar Freire-Agulleiro, Vitor Ferreira, María Silveira-Loureiro, Eva Rial-Pensado, Roger J Davis

Mol Metab· August 2025

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Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity.
Tigist Y Tamir, Shreya Chaudhary, Annie X Li, Sonia E Trojan, Cameron T Flower, Jeffrey C Davis, Roger J Davis

Mol Cell· June 2025

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Mixed lineage kinase (MLK) controls tumor development and angiogenesis.
Shashi Kant, Amada D Caliz, Hyung-Jin Yoo, Gaganpreet Kaur, Heather Learnard, Roger J Davis

Angiogenesis· May 2025

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Bipartite binding of the intrinsically disordered scaffold protein JIP1 to the kinase JNK1.
Thibault Orand, Elise Delaforge, Alexandra Lee, Jaka Kragelj, Maud Tengo, Roger J Davis

Proc Natl Acad Sci U S A· March 2025

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Selective genetic inactivation of Caspase 8 in hepatocytes ameliorates progression of MASH following Jnk deficiency.
Ines Volkert, Julia Grube, Marius Maximilian Woitok, Mohamed Ramadan Mohamed, Karolina Edlund, Roger J Davis

Hepatology· February 2025

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G-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis.
Srinivas Pittala, Dhanush Haspula, Yinghong Cui, Won-Mo Yang, Young-Bum Kim, Roger J Davis

Nat Commun· November 2024

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Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1.
Laura Mariño Pérez, Francesco S Ielasi, Alexandra Lee, Elise Delaforge, Pauline Juyoux, Roger J Davis

Structure· September 2024

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Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity.
Tigist Y Tamir, Shreya Chaudhary, Annie X Li, Sonia E Trojan, Cameron T Flower, Jeffrey C Davis, Roger J Davis

bioRxiv· August 2024

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JNKs protect from cholestatic liver disease progression by modulating Apelin signalling.
Mohamed Ramadan Mohamed, Johannes Haybaeck, Hanghang Wu, Huan Su, Matthias Bartneck, Roger J Davis

JHEP Rep· November 2023

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Correction: Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.
Xuchen Zhang, Peiying Shan, Leo E Otterbein, Jawed Alam, Richard A Flavell, Roger J Davis

J Biol Chem· October 2023

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Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.
Vitor Ferreira, Cintia Folgueira, María García-Altares, Maria Guillén, Mónica Ruíz-Rosario, Roger J Davis

Redox Biol· July 2023

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HER2-driven breast cancer suppression by the JNK signaling pathway.
Zeynep Itah, Shanzah Chaudhry, Sithara Raju Ponny, Ozkan Aydemir, Alexandra Lee, Roger J Davis

Proc Natl Acad Sci U S A· January 2023

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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.
Santiago Vernia, Alexandra Lee, Norman J Kennedy, Myoung Sook Han, Marta Isasa, Roger J Davis

Proc Natl Acad Sci U S A· November 2022

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Mixed lineage kinase 3 requires a functional CRIB domain for regulation of blood pressure, cardiac hypertrophy, and left ventricular function.
Pei-Wen Liu, Gregory L Martin, Weiyu Lin, Wanting Huang, Suchita Pande, Roger J Davis

Am J Physiol Heart Circ Physiol· September 2022

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Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition.
Doo Soon Im, Alvin Joselin, Devon Svoboda, Tesuya Takano, Maxime W C Rousseaux, Roger J Davis

BMC Biol· May 2022

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c-JUN n-Terminal Kinase (JNK) Signaling in Autosomal Dominant Polycystic Kidney Disease.
Abigail O Smith, Julie A Jonassen, Kenley M Preval, Roger J Davis, Gregory J Pazour

J Cell Signal· January 2022

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Aberrant Ca signaling by IPRs in adipocytes links inflammation to metabolic dysregulation in obesity.
Ekin Guney, Ana Paula Arruda, Günes Parlakgul, Erika Cagampan, Nina Min, Roger J Davis

Sci Signal· December 2021

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c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.
Abigail O Smith, Julie A Jonassen, Kenley M Preval, Roger J Davis, Gregory J Pazour

PLoS Genet· December 2021

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Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease.
Chaobo Chen, Hanghang Wu, Hui Ye, Agustín Tortajada, Sandra Rodríguez-Perales, Roger J Davis

Cancers (Basel)· December 2021

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MLK3 mediates impact of PKG1α on cardiac function and controls blood pressure through separate mechanisms.
Timothy D Calamaras, Suchita Pande, Robert Au Baumgartner, Seung Kyum Kim, Joseph C McCarthy, Roger J Davis

JCI Insight· September 2021

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Mitogen Kinase Kinase (MKK7) Controls Cytokine Production In Vitro and In Vivo in Mice.
Amada D Caliz, Hyung-Jin Yoo, Anastassiia Vertii, Ana C Dolan, Cathy Tournier, Roger J Davis

Int J Mol Sci· August 2021

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JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Katrin Müller, Hanna Honcharova-Biletska, Christiane Koppe, Michèle Egger, Lap Kwan Chan, Roger J Davis

Proc Natl Acad Sci U S A· March 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Roger J Davis, Tanja Davis

Autophagy· January 2021

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