Publications by authors named "Roger M Mason"

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Fell-Muir lecture: Connective tissue growth factor (CCN2) -- a pernicious and pleiotropic player in the development of kidney fibrosis.
Roger M Mason

Int J Exp Pathol· February 2013

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Hyperglycemia causes renal cell damage via CCN2-induced activation of the TrkA receptor: implications for diabetic nephropathy.
Maria Fragiadaki, Nicola Hill, Reiko Hewitt, George Bou-Gharios, Terence Cook, Roger M Mason

Diabetes· September 2012

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Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo.
Maria Fragiadaki, Abigail S Witherden, Tomoyo Kaneko, Sonali Sonnylal, Charles D Pusey, Roger M Mason

Matrix Biol· September 2011

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High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1.
Maria Fragiadaki, Tetsurou Ikeda, Abigail Witherden, Roger M Mason, David Abraham

Mol Biol Cell· June 2011

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Epithelial-mesenchymal transition in renal fibrosis - evidence for and against.
Maria Fragiadaki, Roger M Mason

Int J Exp Pathol· June 2011

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Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?
Roger M Mason

J Cell Commun Signal· June 2009

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Connective tissue growth factor (CTGF) promotes activated mesangial cell survival via up-regulation of mitogen-activated protein kinase phosphatase-1 (MKP-1).
Nadia Wahab, Dimity Cox, Abigail Witherden, Roger M Mason

Biochem J· August 2007

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Inhibitory effect of statins on renal epithelial-to-mesenchymal transition.
Sharmila Patel, Roger M Mason, Jun Suzuki, Atsushi Imaizumi, Takashi Kamimura

Am J Nephrol· December 2006

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A critical look at growth factors and epithelial-to-mesenchymal transition in the adult kidney. Interrelationships between growth factors that regulate EMT in the adult kidney.
Nadia A Wahab, Roger M Mason

Nephron Exp Nephrol· December 2006

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RhoGTPase activation is a key step in renal epithelial mesenchymal transdifferentiation.
Sharmila Patel, Ken-ichro Takagi, Jun Suzuki, Atsushi Imaizumi, Tsuyoshi Kimura, Roger M Mason

J Am Soc Nephrol· July 2005

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Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2.
Nadia Abdel Wahab, Benjamin S Weston, Roger M Mason

Exp Cell Res· July 2005

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TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT).
Hidenori Kasai, Jeremy T Allen, Roger M Mason, Takashi Kamimura, Zhi Zhang

Respir Res· June 2005

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Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA.
Nadia Abdel Wahab, Benjamin S Weston, Roger M Mason

J Am Soc Nephrol· February 2005

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Oncostatin M, a cytokine released by activated mononuclear cells, induces epithelial cell-myofibroblast transdifferentiation via Jak/Stat pathway activation.
Joanna Nightingale, Sharmila Patel, Naotaka Suzuki, Roger Buxton, Ken-ichro Takagi, Roger M Mason

J Am Soc Nephrol· January 2004

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Connective tissue growth factor and renal diseases: some answers, more questions.
Nadia Abdel Wahab, Roger M Mason

Curr Opin Nephrol Hypertens· January 2004

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Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy.
Kristen M Clements, Joanne S Price, Mark G Chambers, Denise M Visco, A Robin Poole, Roger M Mason

Arthritis Rheum· December 2003

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Extracellular matrix metabolism in diabetic nephropathy.
Roger M Mason, Nadia Abdel Wahab

J Am Soc Nephrol· May 2003

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CTGF mediates TGF-beta-induced fibronectin matrix deposition by upregulating active alpha5beta1 integrin in human mesangial cells.
Benjamin S Weston, Nadia Abdel Wahab, Roger M Mason

J Am Soc Nephrol· March 2003

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Connective tissue growth factor and regulation of the mesangial cell cycle: role in cellular hypertrophy.
Nadia Abdel-Wahab, Benjamin S Weston, Terry Roberts, Roger M Mason

J Am Soc Nephrol· October 2002

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Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240.
Nadia Abdel-Wahab, Stephen J Wicks, Roger M Mason, Andrew Chantry

Biochem J· March 2002

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Thrombospondin-1 is the key activator of TGF-beta1 in human mesangial cells exposed to high glucose.
Natalia Yevdokimova, Nadia Abdel Wahab, Roger M Mason

J Am Soc Nephrol· April 2001

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The decorin high glucose response element and mechanism of its activation in human mesangial cells.
Nadia Abdel Wahab, Susan Parker, Jean-Daniel Sraer, Roger M Mason

J Am Soc Nephrol· September 2000

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