Publications by authors named "Roger MacKenzie"

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Correction to: Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct.
Kevin A Henry, Henk van Faassen, Doreen Harcus, Anne Marcil, Jennifer J Hill, C Roger MacKenzie

Immunogenetics· April 2023

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Llama DNA Immunization and Isolation of Functional Single-Domain Antibody Binders.
Frédéric Trempe, Martin A Rossotti, Tahir Maqbool, C Roger MacKenzie, Mehdi Arbabi-Ghahroudi

Methods Mol Biol· February 2022

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Biparatopic single-domain antibodies against Axl achieve ultra-high affinity through intramolecular engagement.
Kevin A Henry, Thanh-Dung Nguyen, Toya Nath Baral, Greg Hussack, Shalini Raphael, C Roger MacKenzie

Biochem Biophys Res Commun· July 2021

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Incorporation of a Novel CD16-Specific Single-Domain Antibody into Multispecific Natural Killer Cell Engagers With Potent ADCC.
Henk van Faassen, Dong-Hyeon Jo, Shannon Ryan, Michael J Lowden, Shalini Raphael, C Roger MacKenzie

Mol Pharm· June 2021

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Serum albumin-binding V Hs with variable pH sensitivities enable tailored half-life extension of biologics.
Henk van Faassen, Shannon Ryan, Kevin A Henry, Shalini Raphael, Qingling Yang, C Roger MacKenzie

FASEB J· June 2020

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Antibody Binding to the O-Specific Antigen of Pseudomonas aeruginosa O6 Inhibits Cell Growth.
Gabrielle Richard, C Roger MacKenzie, Kevin A Henry, Evgeny Vinogradov, J Christopher Hall

Antimicrob Agents Chemother· March 2020

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Role of the non-hypervariable FR3 D-E loop in single-domain antibody recognition of haptens and carbohydrates.
Kevin A Henry, Greg Hussack, Jyothi Kumaran, Michel Gilbert, C Roger MacKenzie

J Mol Recognit· November 2019

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Neutralization of Clostridium difficile toxin B with VHH-Fc fusions targeting the delivery and CROPs domains.
Greg Hussack, Shannon Ryan, Henk van Faassen, Martin Rossotti, C Roger MacKenzie

PLoS One· May 2019

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Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct.
Kevin A Henry, Henk van Faassen, Doreen Harcus, Anne Marcil, Jennifer J Hill, C Roger MacKenzie

Immunogenetics· April 2019

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Single-Domain Antibodies as Therapeutic and Imaging Agents for the Treatment of CNS Diseases.
Kasandra Bélanger, Umar Iqbal, Jamshid Tanha, Roger MacKenzie, Maria Moreno

Antibodies (Basel)· April 2019

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Editorial: Single-Domain Antibodies-Biology, Engineering and Emerging Applications.
Kevin A Henry, C Roger MacKenzie

Front Immunol· February 2019

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Antigen recognition by single-domain antibodies: structural latitudes and constraints.
Kevin A Henry, C Roger MacKenzie

MAbs· February 2019

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Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Omid Haji-Ghassemi, Sven Müller-Loennies, Cory L Brooks, C Roger MacKenzie, Nathanael Caveney

Biochemistry· February 2019

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Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.
Martin A Rossotti, Kevin A Henry, Henk van Faassen, Jamshid Tanha, Deborah Callaghan, C Roger MacKenzie

Biochem J· January 2019

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Stability-Diversity Tradeoffs Impose Fundamental Constraints on Selection of Synthetic Human V/V Single-Domain Antibodies from Display Libraries.
Kevin A Henry, Dae Young Kim, Hiba Kandalaft, Michael J Lowden, Qingling Yang, C Roger MacKenzie

Front Immunol· December 2017

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A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display.
Greg Hussack, Toya Nath Baral, Jason Baardsnes, Henk van Faassen, Shalini Raphael, C Roger MacKenzie

Front Immunol· October 2017

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A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies.
Kevin A Henry, Traian Sulea, Henk van Faassen, Greg Hussack, Enrico O Purisima, C Roger MacKenzie

PLoS One· August 2017

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Isolation of TGF-β-neutralizing single-domain antibodies of predetermined epitope specificity using next-generation DNA sequencing.
Kevin A Henry, Greg Hussack, Cathy Collins, John C Zwaagstra, Jamshid Tanha, C Roger MacKenzie

Protein Eng Des Sel· October 2016

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Isolation of Camelid Single-Domain Antibodies Against Native Proteins Using Recombinant Multivalent Peptide Ligands.
Norah A Alturki, Kevin A Henry, C Roger MacKenzie, Mehdi Arbabi-Ghahroudi

Methods Mol Biol· June 2016

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Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease.
Hiba Kandalaft, Greg Hussack, Annie Aubry, Henk van Faassen, Yonghong Guan, Roger MacKenzie

Appl Microbiol Biotechnol· October 2015

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High affinity anti-Internalin B VHH antibody fragments isolated from naturally and artificially immunized repertoires.
Robert W Gene, Jyothi Kumaran, Cristina Aroche, Henk van Faassen, J Christopher Hall, C Roger MacKenzie

J Immunol Methods· January 2015

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In situ proteolysis, crystallization and preliminary X-ray diffraction analysis of a VHH that binds listeria internalin B.
Ian Huh, Robert Gene, Jyothi Kumaran, C Roger MacKenzie, Cory L Brooks

Acta Crystallogr F Struct Biol Commun· November 2014

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The intrinsic cysteine and histidine residues of the anti-Salmonella antibody Se155-4: a model for the introduction of new functions into antibody-binding sites.
N Martin Young, David C Watson, Anna M Cunningham, C Roger MacKenzie

Protein Eng Des Sel· October 2014

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Protease-resistant single-domain antibodies inhibit Campylobacter jejuni motility.
Greg Hussack, Ali Riazi, Shannon Ryan, Henk van Faassen, Roger MacKenzie

Protein Eng Des Sel· June 2014

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Single-domain antibodies and their utility.
Toya Nath Baral, Roger MacKenzie, Mehdi Arbabi Ghahroudi

Curr Protoc Immunol· November 2013

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