Publications by authors named "Roger Prades"

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New Trends in Brain Shuttle Peptides.
Roger Prades, Meritxell Teixidó, Benjamí Oller-Salvia

Mol Pharm· March 2025

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Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia.
Èlia Vila, Raquel Pinacho, Roger Prades, Teresa Tarragó, Elena Castro

Int J Mol Sci· March 2023

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Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds.
Chiara Pallara, Debora Cabot, Josep Rivas, Sonia Brun, Jesús Seco, Roger Prades

Sci Rep· September 2022

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The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro.
Diede W M Broekaart, Till S Zimmer, Sophie T Cohen, Rianne Tessers, Jasper J Anink, Roger Prades

Biomedicines· August 2022

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The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects.
Diede Wm Broekaart, Alexandra Bertran, Shaobo Jia, Anatoly Korotkov, Oleg Senkov, Roger Prades

J Clin Invest· January 2021

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Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors.
Alexandra Bertran, Danylo Khomiak, Anna Konopka, Emilia Rejmak, Ewa Bulska, Roger Prades

Bioorg Chem· January 2020

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Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation.
Aleyda Benitez-Amaro, Chiara Pallara, Laura Nasarre, Andrea Rivas-Urbina, Sonia Benitez, Roger Prades

Biochim Biophys Acta Biomembr· July 2019

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A MALDI-TOF-based Method for Studying the Transport of BBB Shuttles-Enhancing Sensitivity and Versatility of Cell-Based In Vitro Transport Models.
Pol Arranz-Gibert, Bernat Guixer, Roger Prades, Sonia Ciudad, Ernest Giralt

Sci Rep· March 2019

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HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles.
Pol Arranz-Gibert, Roger Prades, Bernat Guixer, Simón Guerrero, Eyleen Araya

Sci Rep· December 2018

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Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics.
Salvador Guardiola, Roger Prades, Laura Mendieta, Arwin J Brouwer, Jelle Streefkerk

Cell Chem Biol· August 2018

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The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia.
Roger Prades, Eva Munarriz-Cuezva, Leyre Urigüen, Itziar Gil-Pisa, Lídia Gómez

Eur Neuropsychopharmacol· February 2017

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The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia.
Raquel Pinacho, Elia Vila, Roger Prades, Teresa Tarragó, Elena Castro

Schizophr Res· November 2016

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Applying the retro-enantio approach to obtain a peptide capable of overcoming the blood-brain barrier.
Roger Prades, Benjamí Oller-Salvia, Susanne M Schwarzmaier, Javier Selva, María Moros

Angew Chem Int Ed Engl· March 2015

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Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia.
Raquel Pinacho, Elsa M Valdizán, Fuencisla Pilar-Cuellar, Roger Prades, Teresa Tarragó

J Psychiatr Res· November 2014

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Dual system for the central nervous system targeting and blood-brain barrier transport of a selective prolyl oligopeptidase inhibitor.
Meritxell Teixidó, Esther Zurita, Laura Mendieta, Benjamí Oller-Salvia, Roger Prades

Biopolymers· November 2013

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Peptide POP inhibitors for the treatment of the cognitive symptoms of schizophrenia.
Abraham López, Laura Mendieta, Roger Prades, Soledad Royo, Teresa Tarragó

Future Med Chem· September 2013

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Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor.
Roger Prades, Simón Guerrero, Eyleen Araya, Claudia Molina, Edison Salas

Biomaterials· October 2012

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Rational design of a selective covalent modifier of G protein βγ subunits.
Axel L Dessal, Roger Prades, Ernest Giralt, Alan V Smrcka

Mol Pharmacol· January 2011

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N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.
Morteza Malakoutikhah, Roger Prades, Meritxell Teixidó, Ernest Giralt

J Med Chem· March 2010

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A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles.
Meritxell Teixidó, Esther Zurita, Roger Prades, Teresa Tarrago, Ernest Giralt

Adv Exp Med Biol· June 2009

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Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor.
Teresa Tarragó, Nessim Kichik, Birgit Claasen, Roger Prades, Meritxell Teixidó

Bioorg Med Chem· August 2008

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