Publications by authors named "Roger S Lo"

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Retraction Note: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
Amanpreet Kaur, Marie R Webster, Katie Marchbank, Reeti Behera, Abibatou Ndoye, Roger S Lo, Georgina V Long

Nature· November 2025

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Genomic copy-number variants drive apoptotic evasion underlying acquired resistance to immune checkpoint inhibitors.
Mingming Wu, Shiyue Yang, Zhentao Yang, Jian Fan, Shirley H Lomeli, Carlos N Prieto-Granada, Roger S Lo

Immunity· November 2025

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The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance.
Justin L Engel, Xiao Zhang, Mingming Wu, Yan Wang, Jose Espejo Valle-Inclán, Roger S Lo

Cell· October 2024

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Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.
Aayoung Hong, Marco Piva, Sixue Liu, Willy Hugo, Shirley H Lomeli, Skylar J Lo, Roger S Lo

Cancer Discov· July 2024

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Expression of Concern: Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma.
Aayoung Hong, Gatien Moriceau, Lu Sun, Shirley Lomeli, Marco Piva, Roger S Lo

Cancer Discov· July 2024

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A phase 1 study of triple-targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF-mutated cancers.
Alain P Algazi, James Moon, Christopher D Lao, Bartosz Chmielowski, Kari L Kendra, Shirley H Lomeli, Roger S Lo

Cancer· May 2024

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy).
Paolo A Ascierto, Sanjiv S Agarwala, Allison Betof Warner, Marc S Ernstoff, Bernard A Fox, Jérôme Galon, Roger S Lo

J Transl Med· July 2023

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Multi-organ landscape of therapy-resistant melanoma.
Sixue Liu, Prashanthi Dharanipragada, Shirley H Lomeli, Yan Wang, Xiao Zhang, Roger S Lo

Nat Med· May 2023

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Blocking Genomic Instability Prevents Acquired Resistance to MAPK Inhibitor Therapy in Melanoma.
Prashanthi Dharanipragada, Xiao Zhang, Sixue Liu, Shirley H Lomeli, Aayoung Hong, Kara Z Lo, Roger S Lo

Cancer Discov· April 2023

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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH.
King L Hung, Jens Luebeck, Siavash R Dehkordi, Caterina I Colón, Rui Li, Ivy Tsz-Lo Wong, Shirley H Lomeli, Roger S Lo

Nat Genet· November 2022

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).
Paolo A Ascierto, Sanjiv S Agarwala, Christian Blank, Corrado Caracò, Richard D Carvajal, Roger S Lo

J Transl Med· September 2022

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Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance.
Zhentao Yang, Yan Wang, Sixue Liu, Weixian Deng, Shirley H Lomeli, Roger S Lo

Cancer Discov· August 2022

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Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.
Kai Song, Jenna K Minami, Arthur Huang, Siavash R Dehkordi, Shirley H Lomeli, Roger S Lo

Cancer Discov· April 2022

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Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects.
Helena Escuin-Ordinas, Yining Liu, Lu Sun, Willy Hugo, Robert Dimatteo, Roger S Lo

PLoS One· November 2021

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Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy.
Yujue Wang, Sixue Liu, Zhentao Yang, Alain P Algazi, Shirley H Lomeli, Henry Lopez, Roger S Lo

Cancer Cell· October 2021

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Response and recurrence correlates in individuals treated with neoadjuvant anti-PD-1 therapy for resectable oral cavity squamous cell carcinoma.
Sixue Liu, Hannah M Knochelmann, Shirley H Lomeli, Aayoung Hong, Mary Richardson, Chrystal M Paulos, Roger S Lo

Cell Rep Med· October 2021

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Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma.
Hannah M Knochelmann, Joshua D Horton, Sixue Liu, Kent Armeson, John M Kaczmar, Shirley H Lomeli, Roger S Lo, Chrystal M Paulos

Cell Rep Med· October 2021

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).
Paolo A Ascierto, Christian Blank, Reinhard Dummer, Marc S Ernstoff, Soldano Ferrone, Roger S Lo

J Transl Med· June 2021

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SPRED1 deletion confers resistance to MAPK inhibition in melanoma.
Julien Ablain, Sixue Liu, Gatien Moriceau, Roger S Lo, Leonard I Zon

J Exp Med· March 2021

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Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity.
Aayoung Hong, Marco Piva, Sixue Liu, Willy Hugo, Shirley H Lomeli, Skylar J Lo, Roger S Lo

Cancer Discov· March 2021

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Author Correction: Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Eva Pérez-Guijarro, Howard H Yang, Romina E Araya, Rajaa El Meskini, Helen T Michael, Aleksandra M Michalowski, Roger S Lo

Nat Med· February 2021

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Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial.
Alain P Algazi, Megan Othus, Adil I Daud, Roger S Lo, Janice M Mehnert

Nat Med· October 2020

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Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy).
Paolo A Ascierto, Igor Puzanov, Sanjiv S Agarwala, Christian Blank, Richard D Carvajal, Roger S Lo, Georgina V Long

J Transl Med· September 2020

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Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Eva Pérez-Guijarro, Howard H Yang, Romina E Araya, Rajaa El Meskini, Helen T Michael, Aleksandra M Michalowski, Roger S Lo

Nat Med· May 2020

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Trying for a BRAF Slam Dunk.
Antoni Ribas, Roger S Lo

Cancer Discov· May 2020

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