Publications by authors named "Roger Springett"

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Remission spectroscopy resolves the mechanism of action of bedaquiline within living mycobacteria.
Suzanna H Harrison, Rowan C Walters, Chen-Yi Cheung, Roger J Springett, Gregory M Cook

Nat Commun· November 2025

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The peculiar properties of mitochondrial carriers of the SLC25 family.
Edmund R S Kunji, Vasiliki Mavridou, Martin S King, Camila Cimadamore-Werthein, Stephany Jaiquel Baron, Roger Springett

Biochem J· July 2025

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Membrane potential stimulates ADP import and ATP export by the mitochondrial ADP/ATP carrier due to its positively charged binding site.
Vasiliki Mavridou, Martin S King, Andre Bazzone, Roger Springett, Edmund R S Kunji

Sci Adv· November 2024

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Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma.
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Roger J Springett

Nat Cancer· April 2024

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Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping-pong kinetic mechanism.
Camila Cimadamore-Werthein, Stephany Jaiquel Baron, Martin S King, Roger Springett, Edmund Rs Kunji

EMBO Rep· August 2023

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Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade.
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Roger J Springett

bioRxiv· March 2023

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In Silico Modeling of the Mitochondrial Pumping Complexes with Markov State Models.
Roger Springett

Methods Mol Biol· July 2021

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The proton pumping mechanism of the bc complex.
Roger Springett

Biochim Biophys Acta Bioenerg· March 2021

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Thermodynamic efficiency, reversibility, and degree of coupling in energy conservation by the mitochondrial respiratory chain.
Mårten Wikström, Roger Springett

Commun Biol· August 2020

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The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A.
Anna Stepanova, Csaba Konrad, Giovanni Manfredi, Roger Springett, Vadim Ten

J Neurochem· March 2019

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Electron transfer between cytochrome c and the binuclear center of cytochrome oxidase.
Mariana Rocha, Roger Springett

J Theor Biol· January 2019

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Measuring the functionality of the mitochondrial pumping complexes with multi-wavelength spectroscopy.
Mariana Rocha, Roger Springett

Biochim Biophys Acta Bioenerg· January 2019

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Spectral components of detergent-solubilized bovine cytochrome oxidase.
Mariana C Rocha, Roger Springett

Biochim Biophys Acta Bioenerg· August 2018

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Modelling the free energy profile of the mitochondrial ADP/ATP carrier.
Roger Springett, Martin S King, Paul G Crichton, Edmund R S Kunji

Biochim Biophys Acta Bioenerg· November 2017

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Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects.
Petros A Tyrakis, Marie E Yurkovich, Marco Sciacovelli, Evangelia K Papachristou, Hannah R Bridges, Roger Springett

Cell Rep· October 2017

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Corrigendum to "Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier" [Biochim. Biophys. Acta 1857 (2016) 14-22].
Martin S King, Matthew Kerr, Paul G Crichton, Roger Springett, Edmund R S Kunji

Biochim Biophys Acta· December 2016

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Corrigendum to "The transport mechanism of the mitochondrial ADP/ATP carrier" [Biochim. Biophys. Acta 1863/10 (2016) 2379-2393].
Edmund R S Kunji, Antoniya Aleksandrova, Martin S King, Homa Majd, Valerie L Ashton, Roger Springett

Biochim Biophys Acta· December 2016

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The transport mechanism of the mitochondrial ADP/ATP carrier.
Edmund R S Kunji, Antoniya Aleksandrova, Martin S King, Homa Majd, Valerie L Ashton, Roger Springett

Biochim Biophys Acta· October 2016

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Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier.
Martin S King, Matthew Kerr, Paul G Crichton, Roger Springett, Edmund R S Kunji

Biochim Biophys Acta· January 2016

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Novel methods for measuring the mitochondrial membrane potential.
Roger Springett

Methods Mol Biol· October 2015

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MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Siddhesh Aras, Minbo Bai, Icksoo Lee, Roger Springett, Maik Hüttemann

Mitochondrion· January 2015

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Acute mitochondrial inhibition by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) 1/2 inhibitors regulates proliferation.
Maureen O Ripple, Namjoon Kim, Roger Springett

J Biol Chem· February 2013

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Mammalian complex I pumps 4 protons per 2 electrons at high and physiological proton motive force in living cells.
Maureen O Ripple, Namjoon Kim, Roger Springett

J Biol Chem· February 2013

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Cytochrome c is rapidly reduced in the cytosol after mitochondrial outer membrane permeabilization.
Maureen O Ripple, Michelle Abajian, Roger Springett

Apoptosis· May 2010

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Magnetic resonance-coupled fluorescence tomography scanner for molecular imaging of tissue.
Scott C Davis, Brian W Pogue, Roger Springett, Christoph Leussler, Peter Mazurkewitz

Rev Sci Instrum· June 2008

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