Publications by authors named "Rohit B Sharma"

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Dual-Input Regulation of β-Cell Proliferation by ATF6α and Glucose via E2F1.
Huguet V Landa-Galvan, Thalia A Castro, Jahi J Noel, Gabriel Avila Llamas, Rohit B Sharma

Diabetes· January 2026

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Effect of Ergocalciferol on β-Cell Function in New-Onset Type 1 Diabetes: A Secondary Analysis of a Randomized Clinical Trial.
Benjamin Udoka Nwosu, Sadichchha Parajuli, Rohit B Sharma, Austin F Lee

JAMA Netw Open· March 2024

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Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation.
Rachel E Stamateris, Huguet V Landa-Galvan, Rohit B Sharma, Christine Darko, David Redmond

J Clin Invest· September 2023

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Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells.
Jarin T Snyder, Christine Darko, Rohit B Sharma, Laura C Alonso

Front Endocrinol (Lausanne)· February 2022

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Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.
Søs Skovsø, Evgeniy Panzhinskiy, Jelena Kolic, Haoning Howard Cen, Derek A Dionne, Rohit B Sharma

Nat Commun· February 2022

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Ergocalciferol in New-onset Type 1 Diabetes: A Randomized Controlled Trial.
Benjamin Udoka Nwosu, Sadichchha Parajuli, Gabrielle Jasmin, Jody Fleshman, Rohit B Sharma

J Endocr Soc· January 2022

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Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic β-Cells.
Rohit B Sharma, Huguet V Landa-Galván, Laura C Alonso

Diabetes· November 2021

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In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR.
Jérémie Charbord, Lipeng Ren, Rohit B Sharma, Anna Johansson, Rasmus Ågren

Nat Metab· May 2021

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Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells.
Rohit B Sharma, Christine Darko, Laura C Alonso

J Biol Chem· October 2020

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Role of Interferon-γ-Producing Th1 Cells in a Murine Model of Type I Interferon-Independent Autoinflammation Resulting From DNase II Deficiency.
Sudesh Pawaria, Kerstin Nündel, Kevin M Gao, Stephanie Moses, Patricia Busto, Rohit B Sharma

Arthritis Rheumatol· February 2020

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Atf6α impacts cell number by influencing survival, death and proliferation.
Rohit B Sharma, Jarin T Snyder, Laura C Alonso

Mol Metab· September 2019

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DNA Damage Does Not Cause BrdU Labeling of Mouse or Human β-Cells.
Rohit B Sharma, Christine Darko, Xiaoying Zheng, Brian Gablaski, Laura C Alonso

Diabetes· May 2019

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T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets.
Yahui Kong, Rohit B Sharma, Socheata Ly, Rachel E Stamateris, William M Jesdale

Diabetes· May 2018

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In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy.
Sourav R Choudhury, Zachary Fitzpatrick, Anne F Harris, Stacy A Maitland, Jennifer S Ferreira, Rohit B Sharma

Mol Ther· August 2016

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Islet biology, the CDKN2A/B locus and type 2 diabetes risk.
Yahui Kong, Rohit B Sharma, Benjamin U Nwosu, Laura C Alonso

Diabetologia· August 2016

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Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia.
Rachel J Roth Flach, Laura V Danai, Marina T DiStefano, Mark Kelly, Lorena Garcia Menendez, Rohit B Sharma

J Biol Chem· July 2016

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Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Rachel E Stamateris, Rohit B Sharma, Yahui Kong, Pantea Ebrahimpour, Deepika Panday

Diabetes· April 2016

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Insulin demand regulates β cell number via the unfolded protein response.
Rohit B Sharma, Amy C O'Donnell, Rachel E Stamateris, Binh Ha, Karen M McCloskey

J Clin Invest· October 2015

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Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well?
Rohit B Sharma, Laura C Alonso

Curr Diab Rep· June 2014

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Adaptive β-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression.
Rachel E Stamateris, Rohit B Sharma, Douglas A Hollern, Laura C Alonso

Am J Physiol Endocrinol Metab· July 2013

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Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors.
Rohit B Sharma, Qingde Wang, Jaspal S Khillan

Biochem Biophys Res Commun· July 2013

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