Publications by authors named "Rohit R Jadhav"

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Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells.
Ines Sturmlechner, Abhinav Jain, Bin Hu, Rohit R Jadhav, Wenqiang Cao

Nat Commun· July 2025

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Aging trajectories of memory CD8 T cells differ by their antigen specificity.
Ines Sturmlechner, Abhinav Jain, Bin Hu, Rohit R Jadhav, Wenqiang Cao

bioRxiv· July 2024

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PREX1 improves homeostatic proliferation to maintain a naive CD4+ T cell compartment in older age.
Huimin Zhang, Hirohisa Okuyama, Abhinav Jain, Rohit R Jadhav, Bowen Wu

JCI Insight· February 2024

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CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging.
Jun Jin, Yunmei Mu, Huimin Zhang, Ines Sturmlechner, Chenyao Wang, Rohit R Jadhav

Nat Aging· May 2023

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TRIB2 safeguards naive T cell homeostasis during aging.
Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R Jadhav

Cell Rep· March 2023

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Aging-associated HELIOS deficiency in naive CD4 T cells alters chromatin remodeling and promotes effector cell responses.
Huimin Zhang, Rohit R Jadhav, Wenqiang Cao, Isabel N Goronzy, Tuantuan V Zhao

Nat Immunol· January 2023

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PD-1 combination therapy with IL-2 modifies CD8 T cell exhaustion program.
Masao Hashimoto, Koichi Araki, Maria A Cardenas, Peng Li, Rohit R Jadhav

Nature· October 2022

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Corrigendum: Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells.
Bin Hu, Rohit R Jadhav, Claire E Gustafson, Sabine Le Saux, Zhongde Ye

Front Immunol· April 2022

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Reduced chromatin accessibility to CD4 T cell super-enhancers encompassing susceptibility loci of rheumatoid arthritis.
Rohit R Jadhav, Bin Hu, Zhongde Ye, Khushboo Sheth, Xuanying Li

EBioMedicine· February 2022

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Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells.
Bin Hu, Rohit R Jadhav, Claire E Gustafson, Sabine Le Saux, Zhongde Ye

Front Immunol· June 2021

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Histone deficiency and accelerated replication stress in T cell aging.
Chulwoo Kim, Jun Jin, Zhongde Ye, Rohit R Jadhav, Claire E Gustafson

J Clin Invest· June 2021

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Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation.
Zhongde Ye, Yi Shen, Ke Jin, Jingtao Qiu, Bin Hu, Rohit R Jadhav

Nat Commun· February 2021

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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency.
Chulwoo Kim, Rohit R Jadhav, Claire E Gustafson, Megan J Smithey, Alec J Hirsch

Cell Rep· November 2019

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Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade.
Rohit R Jadhav, Se Jin Im, Bin Hu, Masao Hashimoto, Peng Li

Proc Natl Acad Sci U S A· July 2019

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Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells.
Chulwoo Kim, Bin Hu, Rohit R Jadhav, Jun Jin, Huimin Zhang

Cell Rep· November 2018

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Epigenetics of T cell aging.
Jörg J Goronzy, Bin Hu, Chulwoo Kim, Rohit R Jadhav, Cornelia M Weyand

J Leukoc Biol· October 2018

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Regulation of miR-181a expression in T cell aging.
Zhongde Ye, Guangjin Li, Chulwoo Kim, Bin Hu, Rohit R Jadhav

Nat Commun· August 2018

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Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.
Aaron M Horning, Yao Wang, Che-Kuang Lin, Anna D Louie, Rohit R Jadhav

Cancer Res· February 2018

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DNA Methylation Targets Influenced by Bisphenol A and/or Genistein Are Associated with Survival Outcomes in Breast Cancer Patients.
Rohit R Jadhav, Julia Santucci-Pereira, Yao V Wang, Joseph Liu, Theresa D Nguyen

Genes (Basel)· May 2017

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Methyl-binding DNA capture Sequencing for Patient Tissues.
Rohit R Jadhav, Yao V Wang, Ya-Ting Hsu, Joseph Liu, Dawn Garcia

J Vis Exp· October 2016

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Roles of Distal and Genic Methylation in the Development of Prostate Tumorigenesis Revealed by Genome-wide DNA Methylation Analysis.
Yao Wang, Rohit Ramakant Jadhav, Joseph Liu, Desiree Wilson, Yidong Chen

Sci Rep· February 2016

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DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrence.
Aaron M Horning, Julius A Awe, Chiou-Miin Wang, Joseph Liu, Zhao Lai, Rohit R Jadhav

Prostate· November 2015

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Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer.
Rohit R Jadhav, Zhenqing Ye, Rui-Lan Huang, Joseph Liu, Pei-Yin Hsu

Clin Epigenetics· March 2015

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Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer.
Ya-Ting Hsu, Fei Gu, Yi-Wen Huang, Joseph Liu, Jianhua Ruan, Rohit R Jadhav

Clin Cancer Res· November 2013

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Epigenetic deregulation of the anaplastic lymphoma kinase gene modulates mesenchymal characteristics of oral squamous cell carcinomas.
Tze-Ta Huang, Cara B Gonzales, Fei Gu, Ya-Ting Hsu, Rohit R Jadhav

Carcinogenesis· August 2013

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