Publications by authors named "Roland Riek"

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Oxidized MIF is an Alzheimer's disease drug target relaying external risk factors to tau pathology.
Andreas Müller-Schiffmann, Felix Torres, Anatoliy Kitaygorodskyy, Anand Ramani, Argyro Alatza, Roland Riek

Cell Rep Med· December 2025

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ATP Hydrolysis by α-Synuclein Amyloids is Mediated by Enclosing β-Strand.
Lukas Frey, Fiamma Ayelen Buratti, Istvan Horvath, Shraddha Parate, Ranjeet Kumar, Roland Riek

Adv Sci (Weinh)· November 2025

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Impurities in amyloid studies: The power of automated model building within a cautionary tale for structural biologists.
David Rhyner, Lukas Frey, Jiangtao Zhou, Witek Kwiatkowski, Raffaele Mezzenga, Roland Riek

Protein Sci· November 2025

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Structural Insights and Functional Dynamics of β-Lactoglobulin Fibrils.
Rebecca Sternke-Hoffmann, David Rhyner, Genki Terashi, Bilal Muhammad Qureshi, Roland Riek

Nano Lett· November 2025

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Spermine modulation of Alzheimer's Tau and Parkinson's α-synuclein: implications for biomolecular condensation and neurodegeneration.
Xun Sun, Debasis Saha, Xue Wang, Cecilia Mörman, Rebecca Sternke-Hoffmann, Roland Riek

Nat Commun· November 2025

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The Evolution of Functional Amyloids and Their Impact on Host-Microbe Interactions.
Divya Kolli, Saroj K Rout, Roland Riek, Matthew R Chapman

Adv Sci (Weinh)· October 2025

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Super-resolution triple-resonance NMR spectroscopy for the sequential assignment of proteins.
Olivia Gampp, Luca Wenchel, Peter Güntert, Piotr Klukowski, Roland Riek

Sci Adv· August 2025

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Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria.
Tetiana Serdiuk, Yanick Fleischmann, Dhiman Ghosh, Aro Delparente, Viviane Reber, Roland Riek

Nat Commun· August 2025

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Machine learning in NMR spectroscopy.
Piotr Klukowski, Roland Riek, Peter Güntert

Prog Nucl Magn Reson Spectrosc· July 2025

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MR-Based Drug Discovery Pipeline Presented on the Oncogenic Protein KRAS.
Matthias Bütikofer, Felix Torres, Harindranath Kadavath, Nina Gämperli, Marie Jose Abi Saad, Roland Riek

J Am Chem Soc· April 2025

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TNF-α disrupts the malate-aspartate shuttle, driving metabolic rewiring in iPSC-derived enteric neural lineages from Parkinson's Disease patients.
Bruno Ghirotto, Luís Eduardo Gonçalves, Vivien Ruder, Christina James, Elizaveta Gerasimova, Roland Riek

bioRxiv· March 2025

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Homonuclear Super-Resolution NMR Spectroscopy.
Olivia Gampp, Luca Wenchel, Peter Güntert, Roland Riek

Angew Chem Int Ed Engl· December 2024

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The inhibitory action of the chaperone BRICHOS against the α-Synuclein secondary nucleation pathway.
Dhiman Ghosh, Felix Torres, Matthias M Schneider, Dzmitry Ashkinadze, Harindranath Kadavath, Roland Riek

Nat Commun· November 2024

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Super-resolution NMR spectroscopy.
Luca Wenchel, Olivia Gampp, Roland Riek

J Magn Reson· September 2024

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A structural rationale for reversible vs irreversible amyloid fibril formation from a single protein.
Lukas Frey, Jiangtao Zhou, Gea Cereghetti, Marco E Weber, David Rhyner, Roland Riek

Nat Commun· September 2024

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On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation.
Lukas Frey, Dhiman Ghosh, Bilal M Qureshi, David Rhyner, Ricardo Guerrero-Ferreira, Roland Riek

Elife· August 2024

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An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions.
Gea Cereghetti, Vera M Kissling, Lisa M Koch, Alexandra Arm, Claudia C Schmidt, Roland Riek

Dev Cell· July 2024

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Abandon the NAC in α-synuclein.
Michel Goedert, Christian Griesinger, Tiago F Outeiro, Roland Riek, Gunnar F Schröder

Lancet Neurol· July 2024

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The potential role of liquid-liquid phase separation in the cellular fate of the compartments for unconventional protein secretion.
Luis Felipe S Mendes, Carolina O Gimenes, Marília D O da Silva, Saroj K Rout, Roland Riek

Protein Sci· July 2024

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Rapid Protein-Ligand Affinity Determination by Photoinduced Hyperpolarized NMR.
Matthias Bütikofer, Gabriela R Stadler, Harindranath Kadavath, Riccardo Cadalbert, Felix Torres, Roland Riek

J Am Chem Soc· July 2024

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NMR tools to detect protein allostery.
Olivia Gampp, Harindranath Kadavath, Roland Riek

Curr Opin Struct Biol· June 2024

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Systematic identification of structure-specific protein-protein interactions.
Aleš Holfeld, Dina Schuster, Fabian Sesterhenn, Alison K Gillingham, Patrick Stalder, Roland Riek

Mol Syst Biol· June 2024

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Characterization of self-templating catalytic amyloids.
Saroj K Rout, David Rhyner, Jason Greenwald, Roland Riek

Methods Enzymol· May 2024

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Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform.
Wolf Wüster, Pit Gebbers, Alois Renn, Matthias Bütikofer, Sophie Rüdiger, Roland P Riek

Magn Reson (Gott)· May 2024

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Short Peptide Amyloids Are a Potential Sequence Pool for the Emergence of Proteins.
Witek Kwiatkowski, Jason Greenwald, Laura Murzakhmetov, Robert C Robinson, Roland Riek

J Mol Biol· March 2024

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