Publications by authors named "Rolf D Issels"

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Durable response to nivolumab in combination with regional hyperthermia in a patient with PD-L1-negative metastatic head and neck squamous cell carcinoma.
Luc M Berclaz, Anton Burkhard-Meier, Axel Lechner, Michael Völkl, Sinan E Güler, Rolf D Issels

Cancer Immunol Immunother· April 2025

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Regional hyperthermia for soft tissue sarcoma - a survey on current practice, controversies and consensus among 12 European centers.
Siyer Roohani, Felix Ehret, Marcus Beck, Danai P Veltsista, Jacek Nadobny, Rolf D Issels

Int J Hyperthermia· April 2024

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Regional hyperthermia with cisplatin added to gemcitabine versus gemcitabine in patients with resected pancreatic ductal adenocarcinoma: The HEAT randomised clinical trial.
Rolf D Issels, Stefan Boeck, Uwe Pelzer, Ulrich Mansmann, Pirus Ghadjar

Eur J Cancer· March 2023

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VISTA in Soft Tissue Sarcomas: A Perspective for Immunotherapy?
Markus Albertsmeier, Annelore Altendorf-Hofmann, Lars H Lindner, Rolf D Issels, Eric Kampmann

Cancers (Basel)· February 2022

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Immune infiltrates in patients with localised high-risk soft tissue sarcoma treated with neoadjuvant chemotherapy without or with regional hyperthermia: A translational research program of the EORTC 62961-ESHO 95 randomised clinical trial.
Rolf D Issels, Elfriede Noessner, Lars H Lindner, Michael Schmidt, Markus Albertsmeier

Eur J Cancer· November 2021

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Perioperative chemotherapy and regional hyperthermia for high-risk adult-type soft tissue sarcomas.
Lars H Lindner, Jean-Yves Blay, Alexander M M Eggermont, Rolf D Issels

Eur J Cancer· April 2021

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Post-Neoadjuvant Gemcitabine and Cisplatin with Regional Hyperthermia for Patients with Triple-Negative Breast Cancer and Non-pCR after Neoadjuvant Chemotherapy: A Single-Institute Experience.
Oliver Stoetzer, Dorit Di Gioia, Rolf Dieter Issels, Sultan Abdel-Rahman, Ulrich Mansmann

Breast Care (Basel)· April 2021

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Neoadjuvant Chemoradiation Combined with Regional Hyperthermia in Locally Advanced or Recurrent Rectal Cancer.
Oliver J Ott, Cihan Gani, Lars H Lindner, Manfred Schmidt, Ulf Lamprecht, Rolf D Issels

Cancers (Basel)· March 2021

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Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma.
Markus Albertsmeier, Annelore Altendorf-Hofmann, Lars H Lindner, Rolf D Issels, Eric Kampmann

Cancers (Basel)· December 2020

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Systemic antitumor effect by regional hyperthermia combined with low-dose chemotherapy and immunologic correlates in an adolescent patient with rhabdomyosarcoma - a case report.
Rolf D Issels, Lars H Lindner, Michael von Bergwelt-Baildon, Peter Lang, Christoph Rischpler

Int J Hyperthermia· October 2020

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Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial.
Rolf D Issels, Lars H Lindner, Jaap Verweij, Rüdiger Wessalowski, Peter Reichardt

JAMA Oncol· April 2018

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Neo-adjuvant chemotherapy alone or with regional hyperthermia for soft-tissue sarcoma - Authors' reply.
Rolf D Issels, Lars H Lindner, Rüdiger Wessalowski, Ulrich Mansmann

Lancet Oncol· November 2017

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Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.
Dominique Harnicek, Eric Kampmann, Kirsten Lauber, Roman Hennel, Ana Sofia Cardoso Martins, Rolf D Issels

Int J Cancer· July 2016

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Evaluation of several FDG PET parameters for prediction of soft tissue tumour grade at primary diagnosis and recurrence.
Wolfgang P Fendler, Rebecca P Chalkidis, Harun Ilhan, Thomas Knösel, Ken Herrmann, Rolf D Issels

Eur Radiol· August 2015

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Concomitant trimodality therapy of re-irradiation, chemotherapy and regional hyperthermia for a pretreated inoperable sarcoma recurrence.
Minglun LI, Claudia Andrä, Maximilian Niyazi, Rolf D Issels, Sultan Abdel-Rahman

Tumori· July 2015

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Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study.
Martin K Angele, Markus Albertsmeier, Niclas J Prix, Peter Hohenberger, Sultan Abdel-Rahman, Rolf D Issels

Ann Surg· November 2014

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Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerol-based thermosensitive liposomes.
Simone Limmer, Jasmin Hahn, Rebecca Schmidt, Kirsten Wachholz, Anja Zengerle, Rolf D Issels

Pharm Res· September 2014

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Non-ionic Gd-based MRI contrast agents are optimal for encapsulation into phosphatidyldiglycerol-based thermosensitive liposomes.
Martin Hossann, Tungte Wang, Zulfiya Syunyaeva, Michael Wiggenhorn, Anja Zengerle, Rolf D Issels

J Control Release· February 2013

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Proteins and cholesterol lipid vesicles are mediators of drug release from thermosensitive liposomes.
Martin Hossann, Zulfiya Syunyaeva, Rebecca Schmidt, Anja Zengerle, Hansjörg Eibl, Rolf D Issels

J Control Release· September 2012

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Hsp70, a messenger from hyperthermia for the immune system.
Anna Jolesch, Katharina Elmer, Henriette Bendz, Rolf D Issels, Elfriede Noessner

Eur J Cell Biol· January 2012

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Hyperthermia in soft tissue sarcoma.
Lars H Lindner, Rolf D Issels

Curr Treat Options Oncol· March 2011

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Size of thermosensitive liposomes influences content release.
Martin Hossann, Tungte Wang, Michael Wiggenhorn, Rebecca Schmidt, Anja Zengerle, Rolf D Issels

J Control Release· November 2010

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Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study.
Rolf D Issels, Lars H Lindner, Jaap Verweij, Peter Wust, Peter Reichardt

Lancet Oncol· June 2010

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Sarcomas with spindle cell morphology.
Paola Collini, Poul H B Sorensen, Shreyaskumar Patel, Jean-Yves Blay, Rolf D Issels

Semin Oncol· August 2009

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Comparison of radiological and pathohistological response to neoadjuvant chemotherapy combined with regional hyperthermia (RHT) and study of response dependence on the applied thermal parameters in patients with soft tissue sarcomas (STS).
Robert Stahl, Tungte Wang, Lars H Lindner, Sultan Abdel-Rahman, Margareta Santl, Rolf D Issels

Int J Hyperthermia· June 2009

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