Publications by authors named "Roman Polishchuk"

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High-Calorie Diet Accelerates the Liver Tissue Degeneration and Induces Subcutaneous White-to-Brown Fat Conversion in Mice with a Single-Allele Atp7b Mutation.
Qussai Abbas, Elena S Petrova, Nadezhda V Tsymbalenko, Mohammad Al Farroukh, Daria N Magazenkova, Elena V Polishchuk, Roman S Polishchuk

J Nutr· December 2025

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Copper in Human Health and Disease: Insights from Inherited Disorders.
Raffaella Petruzzelli, Elena Polishchuk, Roman Polishchuk

Physiology (Bethesda)· November 2025

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Pharmacological Modulation of Autophagy Corrects Cellular Defects in Pediatric Crohn's Disease.
Mara Creoli, Pietro Buono, Sabrina Cenni, Marianna Casertano, Alessandra Vitale, Roman Polishchuk, Elena Polishchuk

Mol Cell Biol· November 2025

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Impact of liver fibrosis on AAV-mediated gene transfer to mouse hepatocytes.
Rosa Ferriero, Gemma Bruno, Agnese Padula, Simone Pisano, Iolanda Boffa, Elena Polishchuk, Roman Polishchuk

Nat Commun· March 2025

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Prion protein promotes copper toxicity in Wilson disease.
Raffaella Petruzzelli, Federico Catalano, Roberta Crispino, Elena V Polishchuk, Mariantonietta Elia, Roman S Polishchuk

Nat Commun· February 2025

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Copper impairs the intestinal barrier integrity in Wilson disease.
Adriana Fontes, Hannah Pierson, Joanna B Bierła, Carola Eberhagen, Jennifer Kinschel, Roman Polishchuk

Metabolism· September 2024

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A new Caenorhabditis elegans model to study copper toxicity in Wilson disease.
Federico Catalano, Thomas J O'Brien, Aleksandra A Mekhova, Lucia Vittoria Sepe, Mariantonietta Elia, Elena V Polishchuk, Roman S Polishchuk

Traffic· January 2024

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Genistein improves renal disease in a mouse model of nephropathic cystinosis: a comparison study with cysteamine.
Ester De Leo, Anna Taranta, Roberto Raso, Elena Polishchuk, Valentina D'Oria, Roman Polishchuk

Hum Mol Genet· March 2023

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Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders.
Alessandro Fraldi, Fabio Annunziata, Alessia Lombardi, Hermann-Josef Kaiser, Diego Luis Medina, Roman Polishchuk

EMBO J· December 2022

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Full-length ATP7B reconstituted through protein -splicing corrects Wilson disease in mice.
Agnese Padula, Raffaella Petruzzelli, Sasha A Philbert, Stephanie J Church, Federica Esposito, Roman Polishchuk

Mol Ther Methods Clin Dev· September 2022

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The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle.
Simona Ricciardi, Andrea Maria Guarino, Laura Giaquinto, Elena V Polishchuk, Michele Santoro, Roman S Polishchuk

Nature· June 2022

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Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression.
Laura De Rosa, Dominga Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Elena Polishchuk, Roman Polishchuk

Front Genet· May 2022

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Connecting copper and cancer: from transition metal signalling to metalloplasia.
Eva J Ge, Ashley I Bush, Angela Casini, Paul A Cobine, Justin R Cross, Roman Polishchuk

Nat Rev Cancer· February 2022

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TFEB Regulates ATP7B Expression to Promote Platinum Chemoresistance in Human Ovarian Cancer Cells.
Raffaella Petruzzelli, Marta Mariniello, Rossella De Cegli, Federico Catalano, Floriana Guida, Roman S Polishchuk

Cells· January 2022

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Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease.
Antonietta Tarallo, Carla Damiano, Sandra Strollo, Nadia Minopoli, Alessia Indrieri, Elena Polishchuk, Roman Polishchuk

EMBO Mol Med· November 2021

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Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload.
Maria Carmela Filomena, Daniel L Yamamoto, Pierluigi Carullo, Roman Medvedev, Andrea Ghisleni, Roman Polishchuk

Elife· September 2021

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Infantile -Related End-Stage Liver Disease: An Exceptional Wilson Disease Phenotype From Consecutive Generations.
Emanuele Nicastro, Maria Iascone, Angelo Di Giorgio, Jernej Brecelj, Raffaella Petruzzelli, Roman S Polishchuk

JPGN Rep· August 2021

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Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
Cortnie Hartwig, Gretchen Macías Méndez, Shatabdi Bhattacharjee, Alysia D Vrailas-Mortimer, Stephanie A Zlatic, Roman S Polishchuk

J Neurosci· January 2021

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Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B.
Mafalda Concilli, Raffaella Petruzzelli, Silvia Parisi, Federico Catalano, Francesco Sirci, Roman S Polishchuk

Proc Natl Acad Sci U S A· December 2020

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Author Correction: Characterization of the most frequent ATP7B mutation causing Wilson disease in hepatocytes from patient induced pluripotent stem cells.
Silvia Parisi, Elena V Polishchuk, Simona Allocca, Michela Ciano, Anna Musto, Roman S Polishchuk

Sci Rep· June 2020

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Synthetic Lethality Screening Identifies FDA-Approved Drugs that Overcome ATP7B-Mediated Tolerance of Tumor Cells to Cisplatin.
Marta Mariniello, Raffaella Petruzzelli, Luca G Wanderlingh, Raffaele La Montagna, Annamaria Carissimo, Roman S Polishchuk

Cancers (Basel)· March 2020

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Mitochondrial Dynamics of Proximal Tubular Epithelial Cells in Nephropathic Cystinosis.
Domenico De Rasmo, Anna Signorile, Ester De Leo, Elena V Polishchuk, Anna Ferretta, Roman Polishchuk

Int J Mol Sci· December 2019

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Biological Effects of Anodic Oxidation on Titanium Miniscrews: An In Vitro Study on Human Cells.
Giorgio Iodice, Giuseppe Perinetti, Bjorn Ludwig, Elena V Polishchuk, Roman S Polishchuk

Dent J (Basel)· November 2019

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From and to the Golgi - defining the Wilson disease protein road map.
Roman S Polishchuk, Elena V Polishchuk

FEBS Lett· September 2019

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Activity and Trafficking of Copper-Transporting ATPases in Tumor Development and Defense against Platinum-Based Drugs.
Raffaella Petruzzelli, Roman S Polishchuk

Cells· September 2019

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