Publications by authors named "Ron Do"

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Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities.
Min Seo Kim, Injeong Shim, Akl C Fahed, Ron Do, Woong-Yang Park, Pradeep Natarajan, Amit V Khera, Hong-Hee Won

Cell Metab· July 2024

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A high-coverage genome sequence from an archaic Denisovan individual.
Matthias Meyer, Martin Kircher, Marie-Theres Gansauge, Heng Li, Fernando Racimo, Swapan Mallick, Joshua G Schraiber, Flora Jay, Kay Prüfer, Cesare de Filippo

October 2012

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Author Correction: Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.
David S M Lee, Kathleen M Cardone, David Y Zhang, Noah L Tsao, Sarah Abramowitz, Ron Do

Nat Genet· December 2025

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ChatGPT-Assisted Glaucoma Diagnosis: A Health-Equitable Multi-Ancestry Analysis using Visual Field and Optical Coherence Tomography Data.
Andy S Huang, Anthony Fam, Hetince Zhao, Nicole Paulescu, Anna Fabczak-Kubicka, Ron Do

Am J Ophthalmol· December 2025

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Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.
Aeron M Small, Ta-Yu Yang, Shinsuke Itoh, Sébastien Thériault, Line Dufresne, Ron Do, Anna Helgadottir, Christopher J O'Donnell

Nat Genet· December 2025

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Genomics of drug target prioritization for complex diseases.
Robert Chen, Áine Duffy, Ron Do

Nat Rev Genet· November 2025

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Genetic evidence informs the direction of therapeutic modulation in drug development.
Robert Chen, Áine Duffy, Joshua K Park, David Stein, Avner Schlessinger, Ron Do

NPJ Drug Discov· October 2025

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Gene therapy and genome editing for lipoprotein disorders.
Chen Gurevitz, Archna Bajaj, Amit V Khera, Ron Do, Heribert Schunkert

Eur Heart J· September 2025

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Development of a genetic priority score to predict drug side effects using human genetic evidence.
Áine Duffy, Robert Chen, David Stein, Joshua K Park, Matthew Mort, Ron Do

Nat Commun· September 2025

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Genetic analyses of eight complex diseases using predicted continuous representations of disease.
Robert Chen, Ghislain Rocheleau, Ben Omega Petrazzini, Iain S Forrest, Joshua K Park, Ron Do

Cell Rep Methods· August 2025

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Recall by polygenic risk score in two biobanks supports a genomic approach for glaucoma detection.
Janey Wiggs, Louis Pasquale, Hetince Zhao, Nazlee Zebardast, Kanza Aziz, Ron Do

Res Sq· August 2025

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ACE inhibition increases Alzheimer's disease risk by promoting tau phosphorylation.
Min Seo Kim, Sunyoung Park, Jong Ho Kim, Woojae Myung, Minku Song, Ron Do, Dong Keon Yon, Dong-Gyu Jo

medRxiv· August 2025

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Machine learning-based penetrance of genetic variants.
Iain S Forrest, Ha My T Vy, Ghislain Rocheleau, Daniel M Jordan, Ben O Petrazzini, Ron Do

Science· August 2025

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The omnicausal model reveals the highly polyfactorial nature of complex diseases.
Carla Márquez-Luna, Martin Tournaire, Ghislain Rocheleau, Ron Do, Marie Verbanck

medRxiv· August 2025

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Using large-scale population-based data to improve disease risk assessment of clinical variants.
Iain S Forrest, Kuan-Lin Huang, Julie M Eggington, Wendy K Chung, Daniel M Jordan, Ron Do

Nat Genet· July 2025

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AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations.
So Mi Jemma Cho, Michael Levin, Robert Chen, Ryan Samarakoon, Renae Judy, Ron Do

J Am Coll Cardiol· July 2025

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Associations between pathophysiological traits and symptom development in retrospective analysis of V30M and V122I transthyretin amyloidosis.
Sameer U Kini, Ha My Thi Vy, Madhav Subramanian, Parasuram M Krishnamoorthy, Son Q Duong, Ron Do

Int J Cardiol Heart Vasc· June 2025

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Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.
David S M Lee, Kathleen M Cardone, David Y Zhang, Noah L Tsao, Sarah Abramowitz, Ron Do

Nat Genet· April 2025

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Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma.
Keva Li, Nicholas Tolman, Ayellet V Segrè, Kelsey V Stuart, Oana A Zeleznik, Ron Do

Elife· April 2025

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Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma.
Keva Li, Nicholas Tolman, Ayellet V Segrè, Kelsey V Stuart, Oana A Zeleznik, Ron Do

bioRxiv· March 2025

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Trans-ancestral rare variant association study with machine learning-based phenotyping for metabolic dysfunction-associated steatotic liver disease.
Robert Chen, Ben Omega Petrazzini, Áine Duffy, Ghislain Rocheleau, Daniel Jordan, Ron Do

Genome Biol· March 2025

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Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li, Ron Do, Donald W Bowden

Genome Med· March 2025

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Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank.
Kyle Gibson, Iain S Forrest, Ben O Petrazzini, Áine Duffy, Joshua K Park, Ron Do

Atherosclerosis· February 2025

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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants.
Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, Ketrin Gjoni, Adam S Heath, Ron Do, Donald M Lloyd-Jones, Donald W Bowden

J Am Heart Assoc· February 2025

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Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?
Jihye Kim, Jae H Kang, Janey L Wiggs, Hetince Zhao, Keva Li, Ron Do

Invest Ophthalmol Vis Sci· February 2025

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Association between genetically predicted leisure and social activities and cardiovascular disease and other health outcomes.
Soyeon Kim, Hyunwoong Ko, Woojae Myung, Joohyun Yoon, Kiwon Kim, Ron Do

Nat Cardiovasc Res· January 2025

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Ensemble and consensus approaches to prediction of recessive inheritance for missense variants in human disease.
Ben O Petrazzini, Daniel J Balick, Iain S Forrest, Judy Cho, Ghislain Rocheleau, Ron Do

Cell Rep Methods· December 2024

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