PubHawk
October 2012 PMID 22936568

A high-coverage genome sequence from an archaic Denisovan individual.

Matthias Meyer, Martin Kircher, Marie-Theres Gansauge, Heng Li, Fernando Racimo, Swapan Mallick, Joshua G Schraiber, Flora Jay, Kay Prüfer, Cesare de Filippo, Peter H Sudmant, Can Alkan, Qiaomei Fu, Ron Do, Nadin Rohland

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Mentions

159
Peak: 16 in Oct 2022
across 5 sources since Sep 2020

Extended reach

190,550
potential audience

Total likes

315

Video views

4,434

Mentions per month

Sep 2020 – Oct 2025

Where it's discussed

  • News72 articles
  • Blogs46 articles
  • X / Twitter27 posts
  • Facebook11 posts
  • YouTube3 videos

AI synopsis

What people are saying

Overall, the discussions reflect excitement about the high-coverage genome sequence revealing new insights into Denisovans. For example, mentions of 'unlocking ancient secrets' and references to dating and population migrations demonstrate the perceived importance of this research. The tone is both appreciative and curious, emphasizing the contribution to understanding human evolution, though some posts hint at the ongoing nature of this scientific exploration.

AgreementModerate agreement

Most discussions acknowledge the significance of the Denisovan genome sequencing, recognizing it as an important step in understanding archaic humans.

InterestHigh interest

The posts express high curiosity about the findings, mentioning updates, new genome access, and historical context.

EngagementModerate engagement

Some posts delve into technical details like genome coverage and implications for human history, indicating moderate deep engagement.

ImpactModerate impact

While generally positive, discussions suggest the research's potential impact on anthropology and evolutionary science, but some writers view it as incremental rather than revolutionary.

Abstract in brief

  • This research introduces a new method for preparing DNA libraries that enabled scientists to sequence a high-quality, 30x coverage genome of a Denisovan, an extinct relative of Neandertals, revealing very low genetic diversity in these ancient humans.
  • The high-quality genome data allows researchers to estimate that Denisovans had extremely low heterozygosity and to preliminarily date the specimen based on its genetic differences, helping to understand when they lived.
  • The study also provides detailed insights into how Denisovan and Neandertal DNA have mixed into modern humans and identifies key genetic changes that became common in Homo sapiens after diverging from Denisovans.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Federico Pio Fabrizio
@FPFabrizioPhD · X

Fonti: https://t.co/9kyFwS12ji https://t.co/HYSZrX1TnD https://t.co/egyaNELwXo https://t.co/WMMGj4ILZX https://t.co/Ofk3qyuVDS https://t.co/c7H1wF7aYA P.S. scusate in anticipo per eventuali imprecisioni e sentitevi liberi di intervenire quando volete! 15/15 FINE

Oct 3, 2022 · 61 likes · 2 shares · 7,553 followers View post →
Nereide
@Nereide · X

4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 37 likes · 11 shares · 7,903 followers View post →
thespartaNeer
@thespartaNeer · X

ובכן, זה הרבה יותר #השערה שצריך להוכיח מאשר כזו המבוססת בעובדות, זאת כיוון שלא ניתן לעשות הצלבה, למרות שיש גנום כמעט מושלם של ניאנדרטל באיכות טובה. Meyer, M. et al (2013) "A High-Coverage Genome Sequence from an Archaic Denisovan Individual", Science . Vol. 338 (12), pp. 222-226

Sep 1, 2020 · 19 likes · 2,378 followers View post →
Ignacio Martín Lerma
@I_MartinLerma · X

Por último, cabe destacar al grupo de los Denisovanos. Sabemos que se extendieron por Siberia y la parte oriental de Asia. Reciben su nombre de la cueva de Denisova al sur de Siberia y que la habitaron entre hace 200.000 años y 50.000 años. https://t.co/wgauvJ51DY

Mar 10, 2022 · 18 likes · 2 shares · 11,252 followers View post →
窪田 薫
@kaoryu · X

年代決定なんだろうと思って調べてみたら、地化系じゃなかった。autosomal dataなる代物らしい。 Meyer, M. et al. A high-coverage genome sequence from an archaic Denisovan individual. Science 338, 222–226 (2012). https://t.co/oVSe0S838l

Mar 7, 2021 · 3 likes · 1,599 followers View post →
Anirban Maitra
@Aiims1742 · X

Genetic history of an archaic hominin group from Denisova Cave in Siberia @Nature (2010) https://t.co/oSCBi1M5Xm A High-Coverage Genome Sequence from an Archaic Denisovan Individual @ScienceMagazine (2012) https://t.co/4ynV9NhSMz

Oct 3, 2022 · 2 likes · 31,613 followers View post →

All mentions

Denisovans: Understanding Our Ancient Human Relatives

Denisovans are mysterious hominins whose traces live on in modern humans. This video explores their significant role in human evolution, including their impact in regions like Indonesia. Discover how Denisovans may…

Evolucy · Jul 14, 2025 215 views
Ishmail
@mirthministry · X

@e_wile @Raymond06265386 @9mm_smg Citations: The complete genome sequence of a Neanderthal from the Altai Mountains. 2014 The genetic history of Ice Age Europe. 2016 A high-coverage genome sequence from an archaic Denisovan individual. 2012 I could list a dozen more but me thinks your cup is already full

Aug 17, 2024 · 6 followers View post →
BenBio
@BenBioArt · X

News in science. Soon a new genome will be accessible from Denisovan. https://t.co/UHCB9hUcu9

Jul 12, 2024 · 7 followers View post →
شيخ الساده الآريه
@SheikhAbrahams · X

RT @SheikhAbrahams: @Sheikh_Abrahams الدينوسوفان/Denisovan أنقرض قبل حوالي 78KYA~ بابوا/SM-Papuan ورثو أعلى تركيز لأوتوسومالهم وبنسبه تصل إ…

Jan 6, 2023 · 1 share · 260 followers View post →
شيخ الساده الآريه
@SheikhAbrahams · X

@Sheikh_Abrahams الدينوسوفان/Denisovan أنقرض قبل حوالي 78KYA~ بابوا/SM-Papuan ورثو أعلى تركيز لأوتوسومالهم وبنسبه تصل إلى 6% https://t.co/YC9OEHxjs9 https://t.co/ZWA4C9IMcz https://t.co/047kgDoVLc https://t.co/hggTb1V7Iy https://t.co/O6wW3fx62i https://t.co/t7kAsNJahp https://t.co/eZxUSNV323 https://t.co/iEBormneyU

Jan 4, 2023 · 1 share · 260 followers View post →
Monika Landfried
@MomiraMonika · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 4, 2022 · 11 shares · 44,747 followers View post →
Luca
@folucar · X

RT @FPFabrizioPhD: Fonti: https://t.co/9kyFwS12ji https://t.co/HYSZrX1TnD https://t.co/egyaNELwXo https://t.co/WMMGj4ILZX https://t.co/Ofk3…

Oct 4, 2022 · 2 shares · 1,997 followers View post →
La Stefi
@stebenci · X

RT @FPFabrizioPhD: Fonti: https://t.co/9kyFwS12ji https://t.co/HYSZrX1TnD https://t.co/egyaNELwXo https://t.co/WMMGj4ILZX https://t.co/Ofk3…

Oct 3, 2022 · 2 shares · 385 followers View post →
Nereide
@Nereide · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 7,903 followers View post →
J C O V
@CesarVindell · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 731 followers View post →
HERVE
@HERVE73950491 · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 6,844 followers View post →
Federico Pio Fabrizio
@FPFabrizioPhD · X

Fonti: https://t.co/9kyFwS12ji https://t.co/HYSZrX1TnD https://t.co/egyaNELwXo https://t.co/WMMGj4ILZX https://t.co/Ofk3qyuVDS https://t.co/c7H1wF7aYA P.S. scusate in anticipo per eventuali imprecisioni e sentitevi liberi di intervenire quando volete! 15/15 FINE

Oct 3, 2022 · 61 likes · 2 shares · 7,553 followers View post →
Francesca Chiusaroli
@FChiusaroli · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 10,486 followers View post →
VentagliDiParole 
@VentagliP · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 30,173 followers View post →
Monica Agrati
@Monica_Agrati · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 1,332 followers View post →
Aldo Di Zanni
@Aldo_DiZa · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 4,447 followers View post →
Joey Avenger Jr.
@joyfulmath3 · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 205 followers View post →
Anirban Maitra
@Aiims1742 · X

Genetic history of an archaic hominin group from Denisova Cave in Siberia @Nature (2010) https://t.co/oSCBi1M5Xm A High-Coverage Genome Sequence from an Archaic Denisovan Individual @ScienceMagazine (2012) https://t.co/4ynV9NhSMz

Oct 3, 2022 · 2 likes · 31,613 followers View post →
Gally Sussingcowards
@MucJiu · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 165 followers View post →
Rosy's Science Project
@meryrosyu · X

RT @Nereide: 4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 11 shares · 289 followers View post →
Nereide
@Nereide · X

4/5 Pääbo’s seminal work provides a basis for explaining what makes us uniquely human.

Oct 3, 2022 · 37 likes · 11 shares · 7,903 followers View post →
Fathima Gani R
@fgrsmiles · X

A high-coverage genome sequence from an archaic Denisovan individual. https://t.co/Pzi5R9HA31

May 4, 2022 · 99 followers View post →
Miguel ZAM
@mizam82 · X

RT @I_MartinLerma: Por último, cabe destacar al grupo de los Denisovanos. Sabemos que se extendieron por Siberia y la parte oriental de Asi…

Mar 11, 2022 · 2 shares · 2,332 followers View post →
bugabea
@bugabea · X

RT @I_MartinLerma: Por último, cabe destacar al grupo de los Denisovanos. Sabemos que se extendieron por Siberia y la parte oriental de Asi…

Mar 10, 2022 · 2 shares · 2,985 followers View post →
Ignacio Martín Lerma
@I_MartinLerma · X

Por último, cabe destacar al grupo de los Denisovanos. Sabemos que se extendieron por Siberia y la parte oriental de Asia. Reciben su nombre de la cueva de Denisova al sur de Siberia y que la habitaron entre hace 200.000 años y 50.000 años. https://t.co/wgauvJ51DY

Mar 10, 2022 · 18 likes · 2 shares · 11,252 followers View post →
Stefano Berto, PhD
@StefanoBerto83 · X

@guiodic Dipende molto da quanto genome è stato sequenziato e da quanta copertura genomica hai. Il Denovisan e Neanderthal sono gli unici con un decente coverage che permette buone statistiche per definirli specie distinte. https://t.co/z0Y4rNmxI1

Nov 26, 2021 · 7,874 followers View post →
窪田 薫
@kaoryu · X

年代決定なんだろうと思って調べてみたら、地化系じゃなかった。autosomal dataなる代物らしい。 Meyer, M. et al. A high-coverage genome sequence from an archaic Denisovan individual. Science 338, 222–226 (2012). https://t.co/oVSe0S838l

Mar 7, 2021 · 3 likes · 1,599 followers View post →
thespartaNeer
@thespartaNeer · X

ובכן, זה הרבה יותר #השערה שצריך להוכיח מאשר כזו המבוססת בעובדות, זאת כיוון שלא ניתן לעשות הצלבה, למרות שיש גנום כמעט מושלם של ניאנדרטל באיכות טובה. Meyer, M. et al (2013) "A High-Coverage Genome Sequence from an Archaic Denisovan Individual", Science . Vol. 338 (12), pp. 222-226

Sep 1, 2020 · 19 likes · 2,378 followers View post →