Publications by authors named "Ronald D Gorham"

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Purified complement C3b triggers phagocytosis and activation of human neutrophils via complement receptor 1.
Elena Boero, Ronald D Gorham, Emmet A Francis, Jonathan Brand, Lay Heng Teng

Sci Rep· January 2023

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Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition.
Yogesh B Narkhede, Avneesh K Gautam, Rohaine V Hsu, Wilson Rodriguez, Nehemiah T Zewde, Ronald D Gorham

Front Mol Biosci· March 2021

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Staphylococcal Immune Evasion Proteins: Structure, Function, and Host Adaptation.
Kirsten J Koymans, Manouk Vrieling, Ronald D Gorham, Jos A G van Strijp

Curr Top Microbiol Immunol· May 2019

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Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases.
Dani Ac Heesterbeek, Bart W Bardoel, Edward S Parsons, Isabel Bennett, Maartje Ruyken, Ronald D Gorham

EMBO J· February 2019

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Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models.
Seline A Zwarthoff, Evelien T M Berends, Sanne Mol, Maartje Ruyken, Piet C Aerts, Ronald D Gorham

Front Immunol· July 2018

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Virtual Screening of Chemical Compounds for Discovery of Complement C3 Ligands.
Rohith R Mohan, Mark Wilson, Ronald D Gorham, Reed E S Harrison, Vasilios A Morikis

ACS Omega· June 2018

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Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration.
Rohith R Mohan, Andrea P Cabrera, Reed E S Harrison, Ronald D Gorham, Lincoln V Johnson

Mol Vis· January 2018

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AESOP: A Python Library for Investigating Electrostatics in Protein Interactions.
Reed E S Harrison, Rohith R Mohan, Ronald D Gorham, Chris A Kieslich, Dimitrios Morikis

Biophys J· May 2017

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Let's Tie the Knot: Marriage of Complement and Adaptive Immunity in Pathogen Evasion, for Better or Worse.
Kaila M Bennett, Suzan H M Rooijakkers, Ronald D Gorham

Front Microbiol· January 2017

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Quantitative Modeling of the Alternative Pathway of the Complement System.
Nehemiah Zewde, Ronald D Gorham, Angel Dorado, Dimitrios Morikis

PLoS One· August 2016

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Discovery of Small Molecules for Fluorescent Detection of Complement Activation Product C3d.
Ronald D Gorham, Vicente Nuñez, Jung-Hsin Lin, Suzan H M Rooijakkers, Valentine I Vullev

J Med Chem· December 2015

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Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes.
Evelien T M Berends, Ronald D Gorham, Maartje Ruyken, Jasper A Soppe, Hatice Orhan

BMC Biol· November 2015

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Electrostatic Interactions between Complement Regulator CD46(SCR1-2) and Adenovirus Ad11/Ad21 Fiber Protein Knob.
Carl Z Chen, Ronald D Gorham, Zied Gaieb, Dimitrios Morikis

Mol Biol Int· September 2015

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Hybrid flagellin as a T cell independent vaccine scaffold.
Kaila M Bennett, Ronald D Gorham, Veronica Gusti, Lien Trinh, Dimitrios Morikis

BMC Biotechnol· August 2015

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Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex.
Reed E S Harrison, Ronald D Gorham, Dimitrios Morikis

Protein Sci· May 2015

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A theoretical view of the C3d:CR2 binding controversy.
Rohith R Mohan, Ronald D Gorham, Dimitrios Morikis

Mol Immunol· March 2015

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New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics.
Ronald D Gorham, David L Forest, George A Khoury, James Smadbeck, Consuelo N Beecher

J Med Chem· January 2015

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Viral regulators of complement activation: structure, function and evolution.
Hina Ojha, Hemendra Singh Panwar, Ronald D Gorham, Dimitrios Morikis, Arvind Sahu

Mol Immunol· October 2014

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Molecular analysis of the interaction between staphylococcal virulence factor Sbi-IV and complement C3d.
Ronald D Gorham, Wilson Rodriguez, Dimitrios Morikis

Biophys J· March 2014

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Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.
Ronald D Gorham, David L Forest, Phanourios Tamamis, Aliana López de Victoria, Márta Kraszni

Exp Eye Res· November 2013

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Molecular dynamics in drug design: new generations of compstatin analogs.
Phanourios Tamamis, Aliana López de Victoria, Ronald D Gorham, Meghan L Bellows-Peterson, Panayiota Pierou

Chem Biol Drug Des· May 2012

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An evaluation of Poisson-Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data.
Ronald D Gorham, Chris A Kieslich, Aaron Nichols, Noriko U Sausman, Marisse Foronda

Biopolymers· November 2011

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Electrostatic exploration of the C3d-FH4 interaction using a computational alanine scan.
Atlal M El-Assaad, Chris A Kieslich, Ronald D Gorham, Dimitrios Morikis

Mol Immunol· September 2011

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Electrostatic Similarity Determination Using Multiresolution Analysis.
Huseyin Hakkoymaz, Chris A Kieslich, Ronald D Gorham, Dimitrios Gunopulos, Dimitrios Morikis

Mol Inform· August 2011

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A new generation of potent complement inhibitors of the Compstatin family.
Aliana López de Victoria, Ronald D Gorham, Meghan L Bellows-Peterson, Jun Ling, David D Lo

Chem Biol Drug Des· June 2011

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