Publications by authors named "Ronald Grigg"

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Development of novel benzamide class I selective lysine deacetylase inhibitors as potent anticancer agents.
Jason H Gill, Jonathan D Sellars, Paul G Waddell, Steven D Shnyder, Ronald Grigg

J Enzyme Inhib Med Chem· December 2025

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Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism.
Benjamin S Durham, Ronald Grigg, Ian C Wood

J Neurochem· October 2017

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A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines.
Ronald Grigg, Elghareeb E Elboray, Sunisa Akkarasamiyo, Nutthawat Chuanopparat, H Ali Dondas

Chem Commun (Camb)· January 2016

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Histone deacetylase 3 indirectly modulates tubulin acetylation.
Travis Bacon, Caroline Seiler, Marcin Wolny, Ruth Hughes, Peter Watson, Ronald Grigg

Biochem J· December 2015

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Stereoselective Pd(0) catalysed five component cascade synthesis of complex Z,Z-bisallylamines.
Ronald Grigg, Sunisa Akkarasamiyo, Nutthawat Chuanopparat, Elghareeb E Elboray, Moustafa F Aly

Chem Commun (Camb)· March 2013

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Carbophilic 3-component cascades: access to complex bioactive cyclopropyl diindolylmethanes.
Nigel M Groome, Elghareeb E Elboray, Martyn W Inman, H Ali Dondas, Roger M Phillips, Ronald Grigg

Chemistry· February 2013

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Exploiting adamantane as a versatile organic tecton: multicomponent catalytic cascade reactions.
Ronald Grigg, Elghareeb E Elboray, Moustafa F Aly, Hussien H Abbas-Temirek

Chem Commun (Camb)· December 2012

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Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192.
Marjorie Boissinot, Martyn Inman, Aiden Hempshall, Sally R James, Jason H Gill, Ronald Grigg

Leuk Res· October 2012

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Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients.
Justin Gillespie, Sinisa Savic, Chi Wong, Aiden Hempshall, Martyn Inman, Ronald Grigg

Arthritis Rheum· February 2012

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The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1.
Joan S Lewis-Wambi, Helen Kim, Ramona Curpan, Ronald Grigg, Mohammed A Sarker

Mol Pharmacol· October 2011

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Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents.
Ngampong Kongkathip, Narathip Pradidphol, Komkrit Hasitapan, Ronald Grigg, Wei-Chun Kao

J Med Chem· February 2010

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Synthesis of 1-C-(tetra-O-acetyl-beta-d-galactopyranosyl)-2,3-diiodo-1-propene and its reaction with primary amines.
Uthai Sakee, Chiradet Nasuk, Ronald Grigg

Carbohydr Res· October 2009

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Regioselective synthesis of N-aminoisoindolones and mono-N- and di-N,N'-substituted phthalazones utilizing hydrazine nucleophiles in a palladium-catalyzed three-component cascade process.
Ronald Grigg, Visuvanathar Sridharan, Mufakhrul Shah, Simon Mutton, Colin Kilner

J Org Chem· November 2008

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[Cp*IrCl2]2-catalyzed indirect functionalization of alcohols: novel strategies for the synthesis of substituted indoles.
Simon Whitney, Ronald Grigg, Andrew Derrick, Ann Keep

Org Lett· August 2007

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Sequential one-pot bimetallic Ir(III)/Pd(0) catalysed mono-/bis-alkylation and spirocyclisation processes of 1,3-dimethylbarbituric acid and allenes.
Christian Löfberg, Ronald Grigg, Ann Keep, Andrew Derrick, Visuvanathar Sridharan

Chem Commun (Camb)· December 2006

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Efficient solvent-free selective monoalkylation of arylacetonitriles with mono-, bis-, and tris-primary alcohols catalyzed by a Cp*Ir complex.
Christian Löfberg, Ronald Grigg, Mark A Whittaker, Ann Keep, Andrew Derrick

J Org Chem· October 2006

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Development and therapeutic options for the treatment of raloxifene-stimulated breast cancer in athymic mice.
Ruth M O'Regan, Clodia Osipo, Eric Ariazi, Eun Sook Lee, Kathleen Meeke, Ronald Grigg

Clin Cancer Res· April 2006

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Stereoselective palladium-catalyzed four-component cascade synthesis of pyrrolidinyl-, pyrazolidinyl-, and isoxazolidinyl isoquinolines.
H Ali Dondas, Colin W G Fishwick, Xinjie Gai, Ronald Grigg, Colin Kilner

Angew Chem Int Ed Engl· November 2005

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Bimetallic catalytic synthesis of annelated benzazepines.
Laura A T Cleghorn, Ronald Grigg, Colin Kilner, William S MacLachlan, Visvanthar Sridharan

Chem Commun (Camb)· June 2005

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Synthesis of novel rhinacanthins and related anticancer naphthoquinone esters.
Ngampong Kongkathip, Suwaporn Luangkamin, Boonsong Kongkathip, Chak Sangma, Ronald Grigg

J Med Chem· August 2004

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Palladium catalysed [2 + 2 + 1] intramolecular cycloaddition for the preparation of bicyclo[3.3.0]octa-1.5-dien-3-ones from 1,6-diynes.
Ronald Grigg, Lixin Zhang, Simon Collard, Ann Keep

Chem Commun (Camb)· August 2003

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Novel synthesis of fused isoxazolidines via a palladium catalysed allene insertion-intramoleculer 1,3-dipolar cycloaddition cascade reaction.
Tajassas Aftab, Ronald Grigg, Mark Ladlow, Visuvanathar Sridharan, Mark Thornton-Pett

Chem Commun (Camb)· August 2002

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Traceless solid-phase organic synthesis.
Paul Blaney, Ronald Grigg, Visuvanathar Sridharan

Chem Rev· July 2002

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Diastereoselective cascade synthesis of azabicyclo[3.1.0]hexanes from acyclic precursors.
Jutta Böhmer, Ronald Grigg, John D Marchbank

Chem Commun (Camb)· April 2002

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