Publications by authors named "Ronald Heemstra"

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Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).
Jon-Paul Strachan, David C Kombo, Anatoly Mazurov, Ronald Heemstra, Balwinder S Bhatti

Eur J Med Chem· October 2014

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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ.
Agustin Casimiro-Garcia, Ronald J Heemstra, Christopher F Bigge, Jing Chen, Fred A Ciske

Bioorg Med Chem Lett· February 2013

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Discovery of a series of imidazo[4,5-b]pyridines with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ.
Agustin Casimiro-Garcia, Gary F Filzen, Declan Flynn, Christopher F Bigge, Jing Chen, Ronald J Heemstra

J Med Chem· June 2011

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E
Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action.
Chad A Van Huis, Agustin Casimiro-Garcia, Christopher F Bigge, Wayne L Cody, Danette A Dudley, Ronald J Heemstra

Bioorg Med Chem· March 2009

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S
Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors.
Chad A Van Huis, Christopher F Bigge, Agustin Casimiro-Garcia, Wayne L Cody, Danette A Dudley, Ronald J Heemstra

Chem Biol Drug Des· June 2007

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