Publications by authors named "Ronald Lukas"

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Neuroprotective amyloid β N-terminal peptides differentially alter human α7- and α7β2-nicotinic acetylcholine (nACh) receptor single-channel properties.
Catherine F Roberts, Yiwei Cao, Wonpil Im, Robert A Nichols, Ronald J Lukas

Br J Pharmacol· September 2024

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Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells.
Yuan-Bing Huang, Ze-Gang Ma, Chao Zheng, Xiao-Kuang K Ma, Devin H Taylor, Ronald J Lukas

Acta Pharmacol Sin· April 2022

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Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures.
Maegan M Weltzin, Andrew A George, Ronald J Lukas, Paul Whiteaker

PLoS One· October 2021

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Implications of Oligomeric Amyloid-Beta (oAβ) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline.
Andrew A George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Ronald J Lukas

J Neurosci· January 2021

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Cocaine potently blocks neuronal αβ nicotinic acetylcholine receptors in SH-SY5Y cells.
Ze-Gang Ma, Nan Jiang, Yuan-Bing Huang, Xiao-Kuang Ma, Jason Brek Eaton, Ronald J Lukas

Acta Pharmacol Sin· February 2020

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Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms.
Maegan M Weltzin, Andrew A George, Ronald J Lukas, Paul Whiteaker

PLoS One· December 2019

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Attenuation in Nicotinic Acetylcholine Receptor α9 and α10 Subunit Double Knock-Out Mice of Experimental Autoimmune Encephalomyelitis.
Qiang Liu, Minshu Li, Paul Whiteaker, Fu-Dong Shi, Barbara J Morley, Ronald J Lukas

Biomolecules· December 2019

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Alpha6-containing nicotinic acetylcholine receptor is a highly sensitive target of alcohol.
Fenfei Gao, Dejie Chen, Xiaokuang Ma, Sterling Sudweeks, Jordan T Yorgason, Ronald J Lukas

Neuropharmacology· May 2019

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Pharmacological and functional comparisons of α6/α3β2β3-nAChRs and α4β2-nAChRs heterologously expressed in the human epithelial SH-EP1 cell line.
De-Jie Chen, Fen-Fei Gao, Xiao-Kuang Ma, Gang-Gang Shi, Yuan-Bing Huang, Ronald J Lukas

Acta Pharmacol Sin· October 2018

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Roles of Nicotine in the Development of Intracranial Aneurysm Rupture.
Yoshinobu Kamio, Takeshi Miyamoto, Tetsuro Kimura, Kazuha Mitsui, Hajime Furukawa, Ronald J Lukas

Stroke· October 2018

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α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor.
Aaron L Nichols, Kaori Noridomi, Christopher R Hughes, Farzad Jalali-Yazdi, J Brek Eaton, Ronald J Lukas

ACS Chem Biol· September 2018

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Distinctive Roles for α7*- and α9*-Nicotinic Acetylcholine Receptors in Inflammatory and Autoimmune Responses in the Murine Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis.
Qiang Liu, Paul Whiteaker, Barbara J Morley, Fu-Dong Shi, Ronald J Lukas

Front Cell Neurosci· September 2017

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Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1.
Andrew A George, Abigail Bloy, Julie M Miwa, Jon M Lindstrom, Ronald J Lukas

FASEB J· April 2017

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Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists.
Han-Kun Zhang, J Brek Eaton, Allison Fedolak, Hendra Gunosewoyo, Oluseye K Onajole, Ronald J Lukas

Eur J Med Chem· November 2016

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Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III.
Oluseye K Onajole, Gian Paolo Vallerini, J Brek Eaton, Ronald J Lukas, Dani Brunner

ACS Chem Neurosci· June 2016

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Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome.
Matthew J Mulcahy, Sydney B Blattman, Francisco J Barrantes, Ronald J Lukas, Edward Hawrot

PLoS One· May 2016

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Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.
Qinhui Zhang, Yingjie Du, Jianliang Zhang, Xiaojun Xu, Fenqin Xue, Ronald J Lukas

PLoS One· May 2016

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Emamectin is a non-selective allosteric activator of nicotinic acetylcholine receptors and GABAA/C receptors.
Xiaojun Xu, Caraline Sepich, Ronald J Lukas, Guonian Zhu, Yongchang Chang

Biochem Biophys Res Commun· May 2016

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Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy.
Maegan M Weltzin, Jon M Lindstrom, Ronald J Lukas, Paul Whiteaker

Neuropharmacology· March 2016

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Differential α4(+)/(-)β2 Agonist-binding Site Contributions to α4β2 Nicotinic Acetylcholine Receptor Function within and between Isoforms.
Linda M Lucero, Maegan M Weltzin, J Brek Eaton, John F Cooper, Jon M Lindstrom, Ronald J Lukas

J Biol Chem· January 2016

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Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands.
Oluseye K Onajole, J Brek Eaton, Ronald J Lukas, Dani Brunner, Lucinda Thiede

ACS Med Chem Lett· November 2014

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Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.
Li-Fang Yu, Han-Kun Zhang, Barbara J Caldarone, J Brek Eaton, Ronald J Lukas

J Med Chem· October 2014

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Roles for N-terminal extracellular domains of nicotinic acetylcholine receptor (nAChR) β3 subunits in enhanced functional expression of mouse α6β2β3- and α6β4β3-nAChRs.
Bhagirathi Dash, Ming D Li, Ronald J Lukas

J Biol Chem· October 2014

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The novel α7β2-nicotinic acetylcholine receptor subtype is expressed in mouse and human basal forebrain: biochemical and pharmacological characterization.
Milena Moretti, Michele Zoli, Andrew A George, Ronald J Lukas, Francesco Pistillo

Mol Pharmacol· September 2014

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The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.
Li-Fang Yu, J Brek Eaton, Han-Kun Zhang, Emily Sabath, Taleen Hanania, Ronald J Lukas

Pharmacol Res Perspect· April 2014

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