Publications by authors named "Ronit Mazor"

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AAV2 delivery of the gene results in presentation of an HLA-A02:01-restricted T cell epitope potent to induce T cell cytotoxicity.
Susana S Najera, Annalisa Nicastri, Sojin Bing, Abdul Mohin Sajib, Nicola Ternette, Ronit Mazor

Mol Ther Methods Clin Dev· September 2025

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Can Sex-based Variations in the Immune Responses to AAV Gene Therapy Affect Safety and Efficacy? A Review of Current Understanding.
Leila Abdelhamid, Ronit Mazor

AAPS J· September 2025

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Unveiling the sex bias: higher preexisting and neutralizing titers against AAV in females and implications for gene therapy.
Stephanee Warrington, Trish T Hoang, Morten Seirup, Leila Abdelhamid, Hrittal Saha, Ronit Mazor

Gene Ther· July 2025

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Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus.
So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Ronit Mazor

Nat Biomed Eng· February 2024

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Low cross reactivity between wild type and deamidated AAV can lead to false negative results in immune monitoring T-cell assays.
So Jin Bing, Stephanee Warrington, Ronit Mazor

Front Immunol· July 2023

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Differential T cell immune responses to deamidated adeno-associated virus vector.
So Jin Bing, Sune Justesen, Wells W Wu, Abdul Mohin Sajib, Stephanee Warrington, Ronit Mazor

Mol Ther Methods Clin Dev· March 2022

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In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Lu Shan, Nydia Van Dyk, Nantaporn Haskins, Kimberly M Cook, Kim L Rosenthal, Ronit Mazor

Commun Biol· September 2021

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Immunogenicity of Immunotoxins Containing Exotoxin A: Causes, Consequences, and Mitigation.
Ronit Mazor, Ira Pastan

Front Immunol· April 2021

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Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1.
Ronit Mazor, Emily King, Ira Pastan

Cell Immunol· December 2018

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SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors.
Yasmin Leshem, Emily M King, Ronit Mazor, Yoram Reiter, Ira Pastan

Toxins (Basel)· November 2018

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Strategies to Reduce the Immunogenicity of Recombinant Immunotoxins.
Ronit Mazor, Emily M King, Ira Pastan

Am J Pathol· August 2018

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Improving the Efficacy of an Anti-Tac (CD25) Immunotoxin by Exotoxin A Domain II Engineering.
Gilad Kaplan, Ronit Mazor, Fred Lee, Youjin Jang, Yasmin Leshem

Mol Cancer Ther· July 2018

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Low-Dose Methotrexate Prevents Primary and Secondary Humoral Immune Responses and Induces Immune Tolerance to a Recombinant Immunotoxin.
Emily M King, Ronit Mazor, Nicolas Çuburu, Ira Pastan

J Immunol· March 2018

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Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
Ronit Mazor, Emily M King, Masanori Onda, Nicolas Cuburu, Selamawit Addissie

Proc Natl Acad Sci U S A· January 2018

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Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo.
Ronit Mazor, Devorah Crown, Selamawit Addissie, Youjin Jang, Gilad Kaplan

Cell Mol Immunol· May 2017

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Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38.
Ronit Mazor, Gilad Kaplan, Dong Park, Youjin Jang, Fred Lee

Cell Immunol· March 2017

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Role of HLA-DP in the Presentation of Epitopes from the Truncated Bacterial PE38 Immunotoxin.
Ronit Mazor, Selamawit Addissie, Youjin Jang, Chin-Hsien Tai, Jeremy Rose

AAPS J· January 2017

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Dual B- and T-cell de-immunization of recombinant immunotoxin targeting mesothelin with high cytotoxic activity.
Ronit Mazor, Masanori Onda, Dong Park, Selamawit Addissie, Laiman Xiang

Oncotarget· May 2016

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Immunogenicity of therapeutic recombinant immunotoxins.
Ronit Mazor, Masanori Onda, Ira Pastan

Immunol Rev· March 2016

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Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors.
Ronit Mazor, Jingli Zhang, Laiman Xiang, Selamawit Addissie, Prince Awuah

Mol Cancer Ther· December 2015

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Poor correlation between T-cell activation assays and HLA-DR binding prediction algorithms in an immunogenic fragment of Pseudomonas exotoxin A.
Ronit Mazor, Chin-Hsien Tai, Byungkook Lee, Ira Pastan

J Immunol Methods· October 2015

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Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes.
Ronit Mazor, Jaime A Eberle, Xiaobo Hu, Aaron N Vassall, Masanori Onda

Proc Natl Acad Sci U S A· June 2014

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Removing T-cell epitopes with computational protein design.
Chris King, Esteban N Garza, Ronit Mazor, Jonathan L Linehan, Ira Pastan

Proc Natl Acad Sci U S A· June 2014

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Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.
Ronit Mazor, Aaron N Vassall, Jaime A Eberle, Richard Beers, John E Weldon

Proc Natl Acad Sci U S A· December 2012

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Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours.
Ronit Mazor, Avital Korenstein-Ilan, Alexander Barbul, Yael Eshet, Avi Shahadi

Radiat Res· January 2008

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