Publications by authors named "Rooha Contractor"

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Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Keiran S M Smalley, Rooha Contractor, Thiennga K Nguyen, Min Xiao, Robin Edwards

Cancer Res· July 2008

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Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
Marina Konopleva, Julie Watt, Rooha Contractor, Twee Tsao, David Harris

Cancer Res· May 2008

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The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel.
Nikolas K Haass, Katrin Sproesser, Thiennga K Nguyen, Rooha Contractor, C Angelica Medina

Clin Cancer Res· January 2008

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PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Yoko Tabe, Marina Konopleva, Yutaka Kondo, Rooha Contractor, Twee Tsao

Cancer Biol Ther· December 2007

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An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.
Keiran S M Smalley, Rooha Contractor, Nikolas K Haass, Angela N Kulp, G Ekin Atilla-Gokcumen

Cancer Res· January 2007

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Marina Konopleva, Rooha Contractor, Twee Tsao, Ismael Samudio, Peter P Ruvolo

Cancer Cell· November 2006

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PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
Yoko Tabe, Marina Konopleva, Yutaka Kondo, Rooha Contractor, Linhua Jin

Ann Hematol· October 2006

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A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.
Ismael Samudio, Marina Konopleva, Helene Pelicano, Peng Huang, Olga Frolova, Rooha Contractor

Mol Pharmacol· April 2006

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Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells.
Yoko Tabe, Marina Konopleva, Rooha Contractor, Mark Munsell, Wendy D Schober

Blood· February 2006

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Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Marina Konopleva, Yuexi Shi, Linda S Steelman, John G Shelton, Mark Munsell, Rooha Contractor

Cancer Res· November 2005

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A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Rooha Contractor, Ismael J Samudio, Zeev Estrov, David Harris, James A McCubrey

Cancer Res· April 2005

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Evidence of gender-and tissue-specific promoter methylation and the potential for ethinylestradiol-induced changes in Japanese medaka (Oryzias latipes) estrogen receptor and aromatase genes.
Rooha G Contractor, Christy M Foran, Shuanfang Li, Kristine L Willett

J Toxicol Environ Health A· January 2004

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