Publications by authors named "Roopesh Anand"

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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein.
Ondrej Belan, Luke Greenhough, Lucas Kuhlen, Roopesh Anand, Artur Kaczmarczyk

Mol Cell· August 2023

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Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor.
Luke A Greenhough, Chih-Chao Liang, Ondrej Belan, Simone Kunzelmann, Sarah Maslen, Roopesh Anand

Nature· July 2023

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The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining.
Hubert Fleury, Myles K MacEachern, Clara M Stiefel, Roopesh Anand, Colin Sempeck

Mol Cell· May 2023

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POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells.
Ondrej Belan, Marie Sebald, Marek Adamowicz, Roopesh Anand, Aleksandra Vancevska

Mol Cell· December 2022

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Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2.
Swagata Halder, Aurore Sanchez, Lepakshi Ranjha, Giordano Reginato, Ilaria Ceppi, Roopesh Anand

Mol Cell· October 2022

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HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51.
Roopesh Anand, Erika Buechelmaier, Ondrej Belan, Matthew Newton, Aleksandra Vancevska

Nature· January 2022

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Mechanism of mitotic recombination: insights from C. elegans.
Ondrej Belan, Roopesh Anand, Simon J Boulton

Curr Opin Genet Dev· December 2021

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Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis.
Ondrej Belan, George Moore, Artur Kaczmarczyk, Matthew D Newton, Roopesh Anand

STAR Protoc· June 2021

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Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins.
Ondrej Belan, Consuelo Barroso, Artur Kaczmarczyk, Roopesh Anand, Stefania Federico

Mol Cell· March 2021

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Publisher Correction: Regulation of the MLH1-MLH3 endonuclease in meiosis.
Elda Cannavo, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener

Nature· February 2021

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MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
Sheetal Sharma, Roopesh Anand, Xuzhu Zhang, Sofia Francia, Flavia Michelini

Cell Rep· January 2021

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Regulation of the MLH1-MLH3 endonuclease in meiosis.
Elda Cannavo, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener

Nature· October 2020

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The internal region of CtIP negatively regulates DNA end resection.
Sean Michael Howard, Ilaria Ceppi, Roopesh Anand, Roger Geiger, Petr Cejka

Nucleic Acids Res· June 2020

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MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.
Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S Nambiar, Raquel Cuella-Martin, Roopesh Anand

Nat Commun· June 2020

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CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection.
Ilaria Ceppi, Sean M Howard, Kristina Kasaciunaite, Cosimo Pinto, Roopesh Anand

Proc Natl Acad Sci U S A· April 2020

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Competing interaction partners modulate the activity of Sgs1 helicase during DNA end resection.
Kristina Kasaciunaite, Fergus Fettes, Maryna Levikova, Peter Daldrop, Roopesh Anand

EMBO J· July 2019

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NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
Roopesh Anand, Arti Jasrotia, Diana Bundschuh, Sean Michael Howard, Lepakshi Ranjha

EMBO J· April 2019

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Methods to Study DNA End Resection I: Recombinant Protein Purification.
Roopesh Anand, Cosimo Pinto, Petr Cejka

Methods Enzymol· March 2019

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Methods to Study DNA End Resection II: Biochemical Reconstitution Assays.
Cosimo Pinto, Roopesh Anand, Petr Cejka

Methods Enzymol· March 2019

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Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.
Angelo Taglialatela, Silvia Alvarez, Giuseppe Leuzzi, Vincenzo Sannino, Lepakshi Ranjha, Roopesh Anand

Mol Cell· October 2017

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SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Waaqo Daddacha, Allyson E Koyen, Amanda J Bastien, PamelaSara E Head, Vishal R Dhere, Roopesh Anand

Cell Rep· August 2017

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The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.
Jun Hyun Kim, Malgorzata Grosbart, Roopesh Anand, Claire Wyman, Petr Cejka

Cell Rep· January 2017

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Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.
Roopesh Anand, Lepakshi Ranjha, Elda Cannavo, Petr Cejka

Mol Cell· December 2016

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RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.
Huiming Lu, Raghavendra A Shamanna, Guido Keijzers, Roopesh Anand, Lene Juel Rasmussen

Cell Rep· June 2016

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The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions.
Lepakshi Ranjha, Roopesh Anand, Petr Cejka

J Biol Chem· February 2014

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