Publications by authors named "Rosa Cookson"

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Core Modifications of GSK3335103 toward Orally Bioavailable αβ Inhibitors with Improved Synthetic Tractability.
Heather F Hryczanek, John Barrett, Tim N Barrett, Glenn A Burley, Rosa E Cookson

J Med Chem· November 2024

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Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe.
Erin Bradley, Lucia Fusani, Chun-Wa Chung, Peter D Craggs, Emmanuel H Demont, Rosa Cookson

J Med Chem· December 2023

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Small Molecule Ligands of the BET-like Bromodomain, BRD3, Affect Survival, Oviposition, and Development.
Matthias Schiedel, Darius J B McArdle, Gilda Padalino, Anthony K N Chan, Josephine Forde-Thomas, Rosa Cookson

J Med Chem· December 2023

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Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.
Philip G Humphreys, Niall A Anderson, Paul Bamborough, Andrew Baxter, Chun-Wa Chung, Rosa Cookson

J Med Chem· November 2022

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Synthesis of Fluorinated Alkyl Aryl Ethers by Palladium-Catalyzed C-O Cross-Coupling.
Robert Szpera, Patrick G Isenegger, Maxime Ghosez, Natan J W Straathof, Rosa Cookson

Org Lett· August 2020

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Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of -Methylation for PI3Kδ Activity.
Lydia Barnes, Hollie Blaber, David T K Brooks, Lewis Byers, Daniel Buckley, Rosa Cookson

J Med Chem· November 2019

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Sequential Ketene Generation from Dioxane-4,6-dione-keto-dioxinones for the Synthesis of Terpenoid Resorcylates.
Daniel C Elliott, Tsz-Kan Ma, Aymane Selmani, Rosa Cookson, Philip J Parsons

Org Lett· April 2016

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Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors.
Christopher A Natale, Elizabeth K Duperret, Junqian Zhang, Rochelle Sadeghi, Ankit Dahal, Rosa Cookson

Elife· April 2016

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β-Keto-dioxinones and β,δ-diketo-dioxinones in biomimetic resorcylate total synthesis.
Rosa Cookson, Tim N Barrett, Anthony G M Barrett

Acc Chem Res· March 2015

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