Publications by authors named "Roseanne Gerding"

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Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.
Samarjit Patnaik, Kirk L Stevens, Roseanne Gerding, Felix Deanda, J Brad Shotwell

Bioorg Med Chem Lett· June 2009

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Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).
Kyle A Emmitte, Brian J Wilson, Erich W Baum, Holly K Emerson, Kevin W Kuntz, Roseanne M Gerding

Bioorg Med Chem Lett· February 2009

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Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors.
Kirk L Stevens, Krystal J Alligood, Jennifer G Badiang Alberti, Thomas R Caferro, Stanley D Chamberlain, Roseanne M Gerding

Bioorg Med Chem Lett· January 2009

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Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: potent inhibitors of the IGF-1R receptor tyrosine kinase.
Stanley D Chamberlain, Joseph W Wilson, Felix Deanda, Samarjit Patnaik, Anikó M Redman, Roseanne Gerding

Bioorg Med Chem Lett· January 2009

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Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.
Stanley D Chamberlain, Anikó M Redman, Joseph W Wilson, Felix Deanda, J Brad Shotwell, Roseanne Gerding

Bioorg Med Chem Lett· January 2009

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Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: elimination of an acid-mediated decomposition pathway.
Stanley D Chamberlain, Anikó M Redman, Samarjit Patnaik, Keith Brickhouse, Yen-Chiat Chew, Roseanne Gerding

Bioorg Med Chem Lett· January 2009

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Reversible carboxamide-mediated internal activation at C(6) of 2-chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidines.
Stanley D Chamberlain, Roseanne M Gerding, Huangshu Lei, Ganesh Moorthy, Samarjit Patnaik

J Org Chem· December 2008

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