Publications by authors named "Roswitha Beck"

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Studies on the impact of modifications at the Gln-Trp site in RM2-based GRPR ligands.
Sebastian Fischer, Lena Koller, Sandra Dominelli, Roswitha Beck, Hans-Jürgen Wester

EJNMMI Res· September 2025

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(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers.
Sandra Deiser, Sebastian Fenzl, Victor König, Marike Drexler, Lydia M Smith, Roswitha Beck

J Med Chem· August 2024

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Preclinical Evaluation of Gastrin-Releasing Peptide Receptor Antagonists Labeled with Tb and Lu: A Comparative Study.
Nadine Holzleitner, Tatjana Cwojdzinski, Roswitha Beck, Nicole Urtz-Urban, Colin C Hillhouse

J Nucl Med· March 2024

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Significant reduction of activity retention in the kidneys via optimized linker sequences in radiohybrid-based minigastrin analogs.
Nadine Holzleitner, Sebastian Fischer, Isabel Maniyankerikalam, Roswitha Beck, Constantin Lapa

EJNMMI Res· March 2024

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Preclinical Evaluation of Minigastrin Analogs and Proof-of-Concept [Ga]Ga-DOTA-CCK-66 PET/CT in 2 Patients with Medullary Thyroid Cancer.
Thomas Günther, Nadine Holzleitner, Oliver Viering, Roswitha Beck, Georgine Wienand

J Nucl Med· January 2024

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Preclinical Comparison of the Cu- and Ga-Labeled GRPR-Targeted Compounds RM2 and AMTG, as Well as First-in-Humans [Ga]Ga-AMTG PET/CT.
Lena Koller, Markus Joksch, Sarah Schwarzenböck, Jens Kurth, Martin Heuschkel, Roswitha Beck

J Nucl Med· October 2023

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Repetitive Low-Intensity Vestibular Noise Stimulation Partly Reverses Behavioral and Brain Activity Changes following Bilateral Vestibular Loss in Rats.
Max Wuehr, Eva Eilles, Magdalena Lindner, Maximilian Grosch, Roswitha Beck

Biomolecules· October 2023

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Dose- and application route-dependent effects of betahistine on behavioral recovery and neuroplasticity after acute unilateral labyrinthectomy in rats.
Melissa Antons, Magdalena Lindner, Eva Eilles, Lisa Günther, Astrid Delker, Roswitha Beck

Front Neurol· July 2023

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Synthesis and preclinical evaluation of novel Tc-labeled PSMA ligands for radioguided surgery of prostate cancer.
Jan-Philip Kunert, Max Müller, Thomas Günther, León Stopper, Nicole Urtz-Urban, Roswitha Beck

EJNMMI Res· January 2023

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Introduction of a SiFA Moiety into the D-Glutamate Chain of DOTA-PP-F11N Results in Radiohybrid-Based CCK-2R-Targeted Compounds with Improved Pharmacokinetics In Vivo.
Nadine Holzleitner, Thomas Günther, Roswitha Beck, Constantin Lapa, Hans-Jürgen Wester

Pharmaceuticals (Basel)· November 2022

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Synthesis and Preclinical Evaluation of Lu-Labeled Radiohybrid PSMA Ligands for Endoradiotherapy of Prostate Cancer.
Alexander Wurzer, Jan-Philip Kunert, Sebastian Fischer, Veronika Felber, Roswitha Beck

J Nucl Med· October 2022

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Substitution of l-Tryptophan by -Methyl-l-Tryptophan in Lu-RM2 Results in Lu-AMTG, a High-Affinity Gastrin-Releasing Peptide Receptor Ligand with Improved In Vivo Stability.
Thomas Günther, Sandra Deiser, Veronika Felber, Roswitha Beck, Hans-Jürgen Wester

J Nucl Med· September 2022

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Optimization of the Pharmacokinetic Profile of [Tc]Tc-N-Bombesin Derivatives by Modification of the Pharmacophoric Gln-Trp Sequence.
Thomas Günther, Matthias Konrad, León Stopper, Jan-Philip Kunert, Sebastian Fischer, Roswitha Beck

Pharmaceuticals (Basel)· September 2022

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Preclinical comparison of four [F, Ga]rhPSMA-7 isomers: influence of the stereoconfiguration on pharmacokinetics.
Alexander Wurzer, Mara Parzinger, Matthias Konrad, Roswitha Beck, Thomas Günther

EJNMMI Res· December 2020

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Radiohybrid Ligands: A Novel Tracer Concept Exemplified by F- or Ga-Labeled rhPSMA Inhibitors.
Alexander Wurzer, Daniel Di Carlo, Alexander Schmidt, Roswitha Beck, Matthias Eiber

J Nucl Med· May 2020

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Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.
Florian Reichart, Oleg V Maltsev, Tobias G Kapp, Andreas F B Räder, Michael Weinmüller, Roswitha Beck

J Med Chem· February 2019

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Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer.
Margret Schottelius, Alexander Wurzer, Katharina Wissmiller, Roswitha Beck, Maximilian Koch

J Nucl Med· January 2019

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Effect of Carbohydration on the Theranostic Tracer PSMA I&T.
Alexander Schmidt, Martina Wirtz, Stefanie Felicitas Färber, Theresa Osl, Roswitha Beck

ACS Omega· July 2018

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Identification of brain regions predicting epileptogenesis by serial [F]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy.
Vera Russmann, Matthias Brendel, Erik Mille, Angela Helm-Vicidomini, Roswitha Beck

Neuroimage Clin· March 2018

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Therapeutic Radiopharmaceuticals Targeting Integrin αvβ6.
Stefanie Felicitas Färber, Alexander Wurzer, Florian Reichart, Roswitha Beck, Horst Kessler

ACS Omega· February 2018

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Imaging of Glial Activation after Unilateral Labyrinthectomy in the Rat: A [F]GE180-PET Study.
Andreas Zwergal, Lisa Günther, Matthias Brendel, Roswitha Beck, Simon Lindner, Sandra Becker-Bense

Front Neurol· December 2017

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Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.
Matthias Brendel, Federico Probst, Anna Jaworska, Felix Overhoff, Viktoria Korzhova, Roswitha Beck

J Nucl Med· June 2016

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N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.
Lisa Günther, Roswitha Beck, Guoming Xiong, Heidrun Potschka, Klaus Jahn

PLoS One· February 2016

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Sequential [(18)F]FDG µPET whole-brain imaging of central vestibular compensation: a model of deafferentation-induced brain plasticity.
Andreas Zwergal, Julia Schlichtiger, Guoming Xiong, Roswitha Beck, Lisa Günther

Brain Struct Funct· January 2016

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The mixed blessing of treating symptoms in acute vestibular failure--evidence from a 4-aminopyridine experiment.
Roswitha Beck, Lisa Günther, Guoming Xiong, Heidrun Potschka, Guido Böning

Exp Neurol· November 2014

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