Publications by authors named "Roswitha Gropp"

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Validation of a model of rheumatoid arthritis using mice reconstituted with patient peripheral blood mononuclear cells.
Paula Schuster-Winkelmann, Veronika Weß, Marietta Schindler, Morten Ø Jensen, David E Shaw, Roswitha Gropp

Dis Model Mech· December 2025

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Autoantibody Profiling in Ulcerative Colitis: Identification of Early Immune Signatures and Disease-Associated Antigens for Improved Diagnosis and Monitoring.
Andreas Weinhaeusel, Jasmin Huber, Silvia Schoenthaler, Florian Beigel, Christa Noehammer, Roswitha Gropp

Int J Mol Sci· April 2025

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Preclinical proof of principle for orally delivered Th17 antagonist miniproteins.
Stephanie Berger, Franziska Seeger, Ta-Yi Yu, Merve Aydin, Huilin Yang, Roswitha Gropp

Cell· August 2024

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NOD/Scid IL2Rγ Mice Reconstituted with PBMCs from Patients with Atopic Dermatitis or Psoriasis Vulgaris Reflect the Respective Phenotype.
Marietta Schindler, Paula Schuster-Winkelmann, Veronika Weß, Sophia Czell, Franziska Rueff, Roswitha Gropp

JID Innov· May 2024

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Humanized NSG Mouse Models as a Preclinical Tool for Translational Research in Inflammatory Bowel Diseases.
Veronika Weß, Paula Schuster-Winkelmann, Yasemin Hazal Karatekin, Simge Malik, Florian Beigel, Roswitha Gropp

Int J Mol Sci· August 2023

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Design of Glycoengineered IL-4 Antagonists Employing Chemical and Biosynthetic Glycosylation.
Sarah Thomas, Juliane E Fiebig, Eva-Maria Kuhn, Dominik S Mayer, Sebastian Filbeck, Roswitha Gropp

ACS Omega· July 2023

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Perception of journal club seminars by medical doctoral students: results from five years of evaluation.
Mara Taverna, Julian Nicolaus Bucher, Maximilian Weniger, Roswitha Gropp, Serene M L Lee

GMS J Med Educ· April 2022

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NOD/scid IL-2Rγ mice reconstituted with peripheral blood mononuclear cells from patients with Crohn's disease reflect the human pathological phenotype.
Anna-Lena Unterweger, Alena Rüscher, Marietta Seuß, Paula Winkelmann, Florian Beigel, Roswitha Gropp

Immun Inflamm Dis· December 2021

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Suppressing Kv1.3 Ion Channel Activity with a Novel Small Molecule Inhibitor Ameliorates Inflammation in a Humanised Mouse Model of Ulcerative Colitis.
Anna-Lena Unterweger, Morten Ø Jensen, Fabrizio Giordanetto, Vishwanath Jogini, Alena Rüschher, Roswitha Gropp

J Crohns Colitis· November 2021

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The PI3K pathway as a therapeutic intervention point in inflammatory bowel disease.
Paula Winkelmann, Anna-Lena Unterweger, Diya Khullar, Florian Beigel, Leandra Koletzko, Roswitha Gropp

Immun Inflamm Dis· September 2021

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Head-to-head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL2Rγnull mice reconstituted with human peripheral blood mononuclear cells.
Henrika Jodeleit, Paula Winkelmann, Janina Caesar, Sebastian Sterz, Lesca M Holdt, Roswitha Gropp

Dis Model Mech· January 2021

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Autoantibodies as diagnostic markers and potential drivers of inflammation in ulcerative colitis.
Henrika Jodeleit, Lisa Milchram, Regina Soldo, Gabriel Beikircher, Silvia Schönthaler, Roswitha Gropp

PLoS One· April 2020

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The Combination of Patient Profiling and Preclinical Studies in a Mouse Model Based on NOD/Scid IL2Rγ null Mice Reconstituted With Peripheral Blood Mononuclear Cells From Patients With Ulcerative Colitis May Lead to Stratification of Patients for Treatment With Adalimumab.
Henrika Jodeleit, Janina Caesar, Christina Villarroel Aguilera, Sebastian Sterz, Lesca Holdt, Roswitha Gropp

Inflamm Bowel Dis· March 2020

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Targeting ulcerative colitis by suppressing glucose uptake with ritonavir.
Henrika Jodeleit, Omar Al-Amodi, Janina Caesar, Christina Villarroel Aguilera, Lesca Holdt, Roswitha Gropp

Dis Model Mech· November 2018

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CD1a-Expressing Monocytes as Mediators of Inflammation in Ulcerative Colitis.
Omar Al-Amodi, Henrika Jodeleit, Florian Beigel, Eckhard Wolf, Matthias Siebeck, Roswitha Gropp

Inflamm Bowel Dis· May 2018

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Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model.
Henrika Jodeleit, Pia Palamides, Florian Beigel, Thomas Mueller, Eckhard Wolf, Roswitha Gropp

J Transl Med· December 2017

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A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals.
Pia Palamides, Henrika Jodeleit, Michael Föhlinger, Florian Beigel, Nadja Herbach, Roswitha Gropp

Dis Model Mech· September 2016

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Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells.
Thomas Nolte, Maryam Zadeh-Khorasani, Orkhan Safarov, Franziska Rueff, Rita Varga, Roswitha Gropp

Dis Model Mech· January 2013

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NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways.
Maryam Zadeh-Khorasani, Thomas Nolte, Thomas D Mueller, Markos Pechlivanis, Franziska Rueff, Roswitha Gropp

J Transl Med· January 2013

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Expression of human beta defensin (HBD-1 and HBD-2) mRNA in nasal epithelia of adult cystic fibrosis patients, healthy individuals, and individuals with acute cold.
Nurlan Dauletbaev, Roswitha Gropp, Michaela Frye, Stefan Loitsch, Thomas-Otto-Friedrich Wagner

Respiration· March 2002

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