Publications by authors named "Roy Kahn"

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DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity.
Ewa Cendrowicz, Lisa Jacob, Shirley Greenwald, Ami Tamir, Iris Pecker, Roy Kahn

J Exp Clin Cancer Res· March 2022

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The specificity of Av3 sea anemone toxin for arthropods is determined at linker DI/SS2-S6 in the pore module of target sodium channels.
Maya Gur Barzilai, Roy Kahn, Noa Regev, Dalia Gordon, Yehu Moran

Biochem J· October 2014

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Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels.
Maya Gur, Roy Kahn, Izhar Karbat, Noa Regev, Jinti Wang

J Biol Chem· October 2011

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Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor.
Jinti Wang, Vladimir Yarov-Yarovoy, Roy Kahn, Dalia Gordon, Michael Gurevitz

Proc Natl Acad Sci U S A· September 2011

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Partial agonist and antagonist activities of a mutant scorpion beta-toxin on sodium channels.
Izhar Karbat, Nitza Ilan, Joel Z Zhang, Lior Cohen, Roy Kahn

J Biol Chem· October 2010

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Positions under positive selection--key for selectivity and potency of scorpion alpha-toxins.
Hagar Weinberger, Yehu Moran, Dalia Gordon, Michael Turkov, Roy Kahn

Mol Biol Evol· May 2010

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Fusion and retrotransposition events in the evolution of the sea anemone Anemonia viridis neurotoxin genes.
Yehu Moran, Hagar Weinberger, Nimrod Lazarus, Maya Gur, Roy Kahn

J Mol Evol· August 2009

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Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins.
Roy Kahn, Izhar Karbat, Nitza Ilan, Lior Cohen, Stanislav Sokolov

J Biol Chem· July 2009

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Intron retention as a posttranscriptional regulatory mechanism of neurotoxin expression at early life stages of the starlet anemone Nematostella vectensis.
Yehu Moran, Hagar Weinberger, Adam M Reitzel, James C Sullivan, Roy Kahn

J Mol Biol· July 2008

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Miniaturization of scorpion beta-toxins uncovers a putative ancestral surface of interaction with voltage-gated sodium channels.
Lior Cohen, Noa Lipstein, Izhar Karbat, Nitza Ilan, Nicolas Gilles, Roy Kahn

J Biol Chem· May 2008

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NMR analysis of interaction of LqhalphaIT scorpion toxin with a peptide corresponding to the D4/S3-S4 loop of insect para voltage-gated sodium channel.
Einat Schnur, Michael Turkov, Roy Kahn, Dalia Gordon, Michael Gurevitz

Biochemistry· January 2008

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Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels.
Yehu Moran, Roy Kahn, Lior Cohen, Maya Gur, Izhar Karbat

Biochem J· August 2007

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The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.
Izhar Karbat, Roy Kahn, Lior Cohen, Nitza Ilan, Nicolas Gilles

FEBS J· April 2007

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The insecticidal potential of scorpion beta-toxins.
Michael Gurevitz, Izhar Karbat, Lior Cohen, Nitza Ilan, Roy Kahn

Toxicon· March 2007

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The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control.
Dalia Gordon, Izhar Karbat, Nitza Ilan, Lior Cohen, Roy Kahn

Toxicon· March 2007

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X-ray structure and mutagenesis of the scorpion depressant toxin LqhIT2 reveals key determinants crucial for activity and anti-insect selectivity.
Izhar Karbat, Michael Turkov, Lior Cohen, Roy Kahn, Dalia Gordon

J Mol Biol· February 2007

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Expression and mutagenesis of the sea anemone toxin Av2 reveals key amino acid residues important for activity on voltage-gated sodium channels.
Yehu Moran, Lior Cohen, Roy Kahn, Izhar Karbat, Dalia Gordon

Biochemistry· July 2006

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