Publications by authors named "Roy Levitt"

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Biosafety and efficacy of Kv7 activating rdHSV-CA8∗ analgesic gene therapy for chronic pain via the intra-articular route in mice.
Roy C Levitt, Munal B Kandel, Gerald Z Zhuang, William F Goins, Konstantinos D Sarantopoulos

Mol Ther· September 2025

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Phospho-CREB Regulation on NMDA Glutamate Receptor 2B and Mitochondrial Calcium Uniporter in the Ventrolateral Periaqueductal Gray Controls Chronic Morphine Withdrawal in Male Rats.
Hyun Yi, Jun Gu, Peter J Hamilton, Shue Liu, Shoumin Zhu, Roy C Levitt

J Neurosci· July 2025

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Sirtuin 3 Mediated by Spinal cMyc-Enhancer of Zeste Homology 2 Pathway Plays an Important Role in Human Immunodeficiency Virus-Related Neuropathic Pain Model.
Xun Zhu, Hyun Yi, Jun Gu, Shue Liu, Kentaro Hayashi, Roy C Levitt

Anesth Analg· September 2024

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Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels.
Gerald Z Zhuang, William F Goins, Munal B Kandel, Marco Marzulli, Mingdi Zhang, Alexandra E Levitt, Roy C Levitt

Front Mol Neurosci· July 2024

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rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.
Munal B Kandel, Gerald Z Zhuang, William F Goins, Marco Marzulli, Mingdi Zhang, Alexandra E Levitt, Roy C Levitt

Front Mol Neurosci· May 2024

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Genome Wide Association Study of Neuropathic Ocular Pain.
Jaxon J Huang, Daniel A Rodriguez, Susan H Slifer, Eden R Martin, Roy C Levitt

Ophthalmol Sci· August 2023

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Role of Tumor Necrosis Factor Receptor 1-Reactive Oxygen Species-Caspase 11 Pathway in Neuropathic Pain Mediated by HIV gp120 With Morphine in Rats.
Kentaro Hayashi, Hyun Yi, Xun Zhu, Shue Liu, Jun Gu, Roy C Levitt

Anesth Analg· April 2023

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Impact of Tumor Necrosis Factor Receptor 1 () Polymorphism on Dry Eye Disease.
Kelly Acuna, Anjalee Choudhary, Elyana Locatelli, Daniel A Rodriguez, Eden R Martin, Roy C Levitt

Biomolecules· January 2023

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Differential Effects of Treatment Strategies in Individuals With Chronic Ocular Surface Pain With a Neuropathic Component.
Sneh Patel, Rhiya Mittal, Elizabeth R Felix, Konstantinos D Sarantopoulos, Roy C Levitt

Front Pharmacol· December 2021

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Corneal Nerve Pathway Function in Individuals with Dry Eye Symptoms.
Anat Galor, Elizabeth R Felix, William Feuer, Roy C Levitt, Constantine D Sarantopoulos

Ophthalmology· April 2021

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Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo.
Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Roy C Levitt

Mamm Genome· December 2020

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Effect of non-invasive intranasal neurostimulation on tear volume, dryness and ocular pain.
Monika Farhangi, Anny Mansim Cheng, Brandon Baksh, Constantine D Sarantopoulos, Elizabeth R Felix, Roy C Levitt

Br J Ophthalmol· September 2020

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Periorbital botulinum toxin A improves photophobia and sensations of dryness in patients without migraine: Case series of four patients.
Nandini Venkateswaran, Jodi Hwang, Andrew J Rong, Alexandra E Levitt, Ryan J Diel, Roy C Levitt

Am J Ophthalmol Case Rep· September 2020

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Transcutaneous Electrical Nerve Stimulation for the Long-Term Treatment of Ocular Pain.
Kristen Zayan, Shruti Aggarwal, Elizabeth Felix, Roy Levitt, Konstantinos Sarantopoulos

Neuromodulation· August 2020

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Oral Gabapentinoids and Nerve Blocks for the Treatment of Chronic Ocular Pain.
Leslie R Small, Anat Galor, Elizabeth R Felix, Danielle B Horn, Roy C Levitt

Eye Contact Lens· May 2020

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Individuals with migraine have a different dry eye symptom profile than individuals without migraine.
Monika Farhangi, Ryan J Diel, Dawn C Buse, Amy Michelle Huang, Roy C Levitt

Br J Ophthalmol· February 2020

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The Genetics of Neuropathic Pain from Model Organisms to Clinical Application.
Margarita Calvo, Alexander J Davies, Harry L Hébert, Greg A Weir, Elissa J Chesler, Roy C Levitt

Neuron· November 2019

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Pregabalin Failed to Prevent Dry Eye Symptoms after Laser-Assisted in Situ Keratomileusis (LASIK) in a Randomized Pilot Study.
Anat Galor, Sneh Patel, Leslie R Small, Adriana Rodriguez, Michael J Venincasa, Roy C Levitt

J Clin Med· September 2019

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Photophobia and sensations of dryness in patients with migraine occur independent of baseline tear volume and improve following botulinum toxin A injections.
Ryan J Diel, Jodi Hwang, Zachary A Kroeger, Roy C Levitt, Constantine D Sarantopoulos

Br J Ophthalmol· August 2019

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Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye).
Monika Farhangi, William Feuer, Anat Galor, Didier Bouhassira, Roy C Levitt

Pain· July 2019

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Resolution of pain with periocular injections in a patient with a 7-year history of chronic ocular pain.
Eric Rh Duerr, Andrew Chang, Nandini Venkateswaran, Raquel Goldhardt, Roy C Levitt

Am J Ophthalmol Case Rep· June 2019

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Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.
Udita Upadhyay, Gerald Z Zhuang, Luda Diatchenko, Marc Parisien, Yuan Kang, Roy C Levitt

PLoS Genet· June 2019

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Dysfunctional Coping Mechanisms Contribute to Dry Eye Symptoms.
Sneh Patel, Elizabeth R Felix, Roy C Levitt, Constantine D Sarantopoulos, Anat Galor

J Clin Med· June 2019

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Epidemiology of Persistent Postsurgical Pain Manifesting as Dry Eye-Like Symptoms After Cataract Surgery.
Ravin Sajnani, Sophia Raia, Allister Gibbons, Victoria Chang, Carol L Karp, Roy C Levitt

Cornea· December 2018

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Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Gerald Z Zhuang, Udita Upadhyay, Xiaoying Tong, Yuan Kang, Diana M Erasso, Roy C Levitt

Gene Ther· July 2018

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