Publications by authors named "Roy Lobb"

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Expression-Dependent Tumor Pretargeting via Engineered Avidity.
Abbigael Harthorn, Tse-Han Kuo, Sarah W Torres, Roy R Lobb, Benjamin J Hackel

Mol Pharm· January 2025

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A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2 Solid Cancer.
Andreas A Hombach, Christine Ambrose, Roy Lobb, Paul Rennert, Hinrich Abken

Cells· January 2023

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CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma.
Lihe Su, Lan Wu, Roy R Lobb, Paul D Rennert, Christine Ambrose

Oncoimmunology· August 2022

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Engineered protein-small molecule conjugates empower selective enzyme inhibition.
Andrew K Lewis, Abbigael Harthorn, Sadie M Johnson, Roy R Lobb, Benjamin J Hackel

Cell Chem Biol· February 2022

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Anti-CD19 CAR T Cells That Secrete a Biparatopic Anti-CLEC12A Bridging Protein Have Potent Activity Against Highly Aggressive Acute Myeloid Leukemia and .
Paul D Rennert, Fay J Dufort, Lihe Su, Tom Sanford, Alyssa Birt, Roy R Lobb

Mol Cancer Ther· October 2021

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Anti-CD19 CAR T cells potently redirected to kill solid tumor cells.
Christine Ambrose, Lihe Su, Lan Wu, Fay J Dufort, Thomas Sanford, Roy R Lobb

PLoS One· September 2021

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Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design.
Justin R Klesmith, Lan Wu, Roy R Lobb, Paul D Rennert, Benjamin J Hackel

Biochemistry· December 2019

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Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins.
Justin R Klesmith, Lihe Su, Lan Wu, Ian A Schrack, Fay J Dufort, Roy R Lobb

Mol Pharm· August 2019

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Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study.
Renata Pasqualini, Randall E Millikan, Dawn R Christianson, Marina Cardó-Vila, Wouter H P Driessen, Roy R Lobb

Cancer· July 2015

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Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer.
Fernanda I Staquicini, Ming D Qian, Ahmad Salameh, Andrey S Dobroff, Julianna K Edwards, Roy R Lobb

J Biol Chem· March 2015

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Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells.
Roberto Rangel, Liliana Guzman-Rojas, Lucia G le Roux, Fernanda I Staquicini, Hitomi Hosoya, Roy R Lobb

Nat Commun· April 2012

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Interferon-beta reduces proteinuria in experimental glomerulonephritis.
Simon C Satchell, Olena Buchatska, Sarah B Khan, Gurjeet Bhangal, Candida H Tasman, Roy R Lobb

J Am Soc Nephrol· November 2007

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Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
Kyungmin Hahm, Matvey E Lukashev, Yi Luo, William J Yang, Brian M Dolinski, Roy R Lobb

Am J Pathol· January 2007

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Rational design of potent and selective VLA-4 inhibitors and their utility in the treatment of asthma.
Juswinder Singh, Steve Adams, Mary Beth Carter, Hernan Cuervo, Wen-Cherng Lee, Roy R Lobb

Curr Top Med Chem· March 2005

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Anti-alpha4 integrin monoclonal antibody inhibits multiple myeloma growth in a murine model.
Dian L Olson, Linda C Burkly, Diane R Leone, Brian M Dolinski, Roy R Lobb

Mol Cancer Ther· January 2005

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Direct evidence of leukocyte adhesion in arterioles by angiotensin II.
Angeles Alvarez, Miguel Cerdá-Nicolás, Yafa Naim Abu Nabah, Manuel Mata, Andrew C Issekutz, Roy R Lobb

Blood· July 2004

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A monoclonal antibody to alpha1beta1 blocks antigen-induced airway responses in sheep.
William M Abraham, Ashfaq Ahmed, Irakli Serebriakov, Amie N Carmillo, Janine Ferrant, Roy R Lobb

Am J Respir Crit Care Med· January 2004

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Blocking VLA-4 prevents progression of experimental crescentic glomerulonephritis.
Sarah B Khan, Andrew R Allen, Gurjeet Bhangal, Jennifer Smith, Roy R Lobb

Nephron Exp Nephrol· January 2004

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Obtustatin: a potent selective inhibitor of alpha1beta1 integrin in vitro and angiogenesis in vivo.
Cezary Marcinkiewicz, Paul H Weinreb, Juan J Calvete, Dariusz G Kisiel, Shaker A Mousa, Roy R Lobb

Cancer Res· May 2003

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Cell-matrix adhesion research and the development of biotherapeutics.
Roy R Lobb

Methods Cell Biol· February 2003

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Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis.
H Terence Cook, Sarah B Khan, Andrew Allen, Gurjeet Bhangal, Jennifer Smith, Roy R Lobb

Am J Pathol· October 2002

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A cell-free electrochemiluminescence assay for measuring beta1-integrin-ligand interactions.
Paul H Weinreb, William J Yang, Shelia M Violette, Megan Couture, Kathleen Kimball, Roy R Lobb

Anal Biochem· July 2002

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Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1.
R Blake Pepinsky, Richard A Mumford, Ling Ling Chen, Diane Leone, Suzanne E Amo, Roy R Lobb

Biochemistry· June 2002

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Rolipram inhibits leukocyte-endothelial cell interactions in vivo through P- and E-selectin downregulation.
María-Jesús Sanz, Angeles Alvarez, Laura Piqueras, Miguel Cerdá, Andrew C Issekutz, Roy R Lobb

Br J Pharmacol· April 2002

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