Publications by authors named "Ru Liu- Bryan"

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Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.
Isidoro Cobo, Jessica Murillo-Saich, Mohnish Alishala, Stephen Calderon, Roxana Coras, Ru Liu Bryan

Immunity· April 2025

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Effective xanthine oxidase inhibitor urate lowering therapy in gout is linked to an emergent serum protein interactome of complement and inflammation modulators.
Concepcion Sanchez, Anaamika Campeau, Ru Liu-Bryan, Ted R Mikuls, James R O'Dell

Sci Rep· October 2024

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Protocol for preparing monosodium urate crystals for in vitro and in vivo studies in mouse and human cells.
Mohnish Alishala, Ru Liu-Bryan, Isidoro Cobo

STAR Protoc· June 2024

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The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target.
Paulo Gil Alabarse, Patricia Oliveira, Huaping Qin, Tiffany Yan, Marie Migaud, Ru Liu-Bryan

Inflamm Res· May 2024

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Effective xanthine oxidase inhibitor urate lowering therapy in gout is linked to an emergent serum protein interactome of complement activation and inflammation modulators.
Concepcion Sanchez, Anaamika Campeau, Ru Liu-Bryan, Ted R Mikuls, James R O'Dell

Res Sq· May 2024

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Synthesis, Detection, and Metabolism of Pyridone Ribosides, Products of NAD Overoxidation.
Faisal Hayat, J Trey Deason, Ru Liu Bryan, Robert Terkeltaub, Weidan Song

Chem Res Toxicol· February 2024

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Sustained xanthine oxidase inhibitor treat to target urate lowering therapy rewires a tight inflammation serum protein interactome.
Concepcion Sanchez, Anamika Campeau, Ru Liu-Bryan, Ted Mikuls, James O'Dell

Res Sq· January 2024

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Amplification of Inflammation by Lubricin Deficiency Implicated in Incident, Erosive Gout Independent of Hyperuricemia.
Khaled Elsaid, Tony R Merriman, Leigh-Ana Rossitto, Ru Liu-Bryan, Jacob Karsh

Arthritis Rheumatol· May 2023

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Targeting CD38 to Suppress Osteoarthritis Development and Associated Pain After Joint Injury in Mice.
Paulo Gil Alabarse, Liang-Yu Chen, Patricia Oliveira, Huaping Qin, Ru Liu-Bryan

Arthritis Rheumatol· March 2023

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A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response.
Tyler A U Hilsabeck, Ru Liu-Bryan, Tracy Guo, Kenneth A Wilson, Neelanjan Bose

Geroscience· August 2022

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Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes.
Monica Guma, Benyamin Dadpey, Roxana Coras, Ted R Mikuls, Bartlett Hamilton, Ru Liu-Bryan

Arthritis Res Ther· July 2022

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Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response.
Isidoro Cobo, Anyan Cheng, Jessica Murillo-Saich, Roxana Coras, Alyssa Torres, Ru Liu-Bryan

Cell Rep· March 2022

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Mitochondrial Biogenesis, Activity, and DNA Isolation in Chondrocytes.
Yun Wang, Liang-Yu Chen, Ru Liu-Bryan

Methods Mol Biol· March 2021

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Cartilage-targeting ultrasmall lipid-polymer hybrid nanoparticles for the prevention of cartilage degradation.
Xiangzhao Ai, Yaou Duan, Qiangzhe Zhang, Derrick Sun, Ronnie H Fang, Ru Liu-Bryan

Bioeng Transl Med· January 2021

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Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout.
Zengmiao Wang, Ying Zhao, Amanda Phipps-Green, Ru Liu-Bryan, Arnoldas Ceponis

Arthritis Rheumatol· May 2020

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Metformin limits osteoarthritis development and progression through activation of AMPK signalling.
Jun Li, Bin Zhang, Wei-Xiao Liu, Ke Lu, Haobo Pan, Ru Liu-Bryan

Ann Rheum Dis· May 2020

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A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia.
Ramon L Serrano, Weifang Yu, Robert M Graham, Ru Liu- Bryan, Robert Terkeltaub

PLoS One· December 2019

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Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Elsa Sanchez-Lopez, Zhenyu Zhong, Alexandra Stubelius, Shannon R Sweeney, Laela M Booshehri, Ru Liu-Bryan

Cell Metab· June 2019

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Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling.
Charles McWherter, Yun-Jung Choi, Ramon L Serrano, Sushil K Mahata, Robert Terkeltaub, Ru Liu-Bryan

Arthritis Res Ther· September 2018

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Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes.
Liang-Yu Chen, Martin Lotz, Robert Terkeltaub, Ru Liu-Bryan

J Biol Chem· August 2018

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Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan.
Ramon L Serrano, Liang-Yu Chen, Martin K Lotz, Ru Liu-Bryan, Robert Terkeltaub

Arthritis Rheumatol· July 2018

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Review: Metabolic Regulation of Inflammation in Osteoarthritis.
Francis Berenbaum, Timothy M Griffin, Ru Liu-Bryan

Arthritis Rheumatol· January 2017

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Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis.
Ronald K June, Ru Liu-Bryan, Fanxing Long, Timothy M Griffin

J Orthop Res· December 2016

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AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis.
Monica Guma, Yun Wang, Benoit Viollet, Ru Liu-Bryan

PLoS One· June 2016

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Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy.
Karen M Doody, Stephanie M Stanford, Cristiano Sacchetti, Mattias N D Svensson, Charlotte H Coles, Ru Liu-Bryan

Sci Transl Med· May 2015

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