Publications by authors named "Rubeshan Perumal"

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Fixed-dose combination bictegravir-emtricitabine-tenofovir alafenamide twice-daily for treatment of HIV during rifampicin-based tuberculosis treatment (INSIGHT Study): a phase 2b, open-label, randomised non-comparative trial.
Anushka Naidoo, Kogieleum Naidoo, Marothi P Letsoalo, Roeland E Wasmann, Gillian Dorse, Rubeshan Perumal

Lancet HIV· December 2025

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The patient pursuit of safe treatment options for tuberculosis.
Rubeshan Perumal, Kogieleum Naidoo

Lancet Infect Dis· November 2025

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The gut and lung microbiome across the TB disease spectrum.
Rubeshan Perumal, Anou M Somboro, Juhi Tulsi, Sinaye Ngcapu, Kogieleum Naidoo

Front Microbiol· October 2025

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Navigating Virology's Frontiers in Africa: Global Virus Network 2024 Durban Meeting.
Maggie L Bartlett, Rubeshan Perumal, Sten H Vermund, Salim Abdool Karim

Viruses· June 2025

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Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Saranathan Rajagopalan, Amy K Rourke, Emmanuel Asare, Donna J Kohlerschmidt, Lahari Das, Rubeshan Perumal

J Infect Dis· April 2025

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First data of a quabodepistat containing novel regimen for drug-susceptible tuberculosis.
Kogieleum Naidoo, Rubeshan Perumal

Lancet Infect Dis· April 2025

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High mortality among patients with tuberculosis accessing primary care facilities: secondary analysis from an open-label cluster-randomised trial.
Kogieleum Naidoo, Nonhlanhla Yende Zuma, Mikaila Moodley, Felix Made, Rubeshan Perumal

EClinicalMedicine· April 2025

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Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/XDR assay for rapid triage and treatment of DR-TB.
Kogieleum Naidoo, Anushka Naidoo, Alash'le G Abimiku, Everdina W Tiemersma, Agnes Gebhard, Rubeshan Perumal

BMJ Open· November 2024

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Are We Capable of Unveiling the Missed Epidemic of Isoniazid-resistant Tuberculosis?
Rubeshan Perumal, Kogieleum Naidoo

Ann Am Thorac Soc· October 2024

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The epidemiology, transmission, diagnosis, and management of drug-resistant tuberculosis-lessons from the South African experience.
Kogieleum Naidoo, Rubeshan Perumal, Helen Cox, Barun Mathema, Marian Loveday

Lancet Infect Dis· September 2024

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Differentiated service delivery framework for people with multidrug-resistant tuberculosis and HIV co-infection.
Karl Reis, Allison Wolf, Rubeshan Perumal, Boitumelo Seepamore, Kevin Guzman

J Acquir Immune Defic Syndr· May 2024

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Opportunities and limitations of genomics for diagnosing bedaquiline-resistant tuberculosis: a systematic review and individual isolate meta-analysis.
Camus Nimmo, Neda Bionghi, Matthew J Cummings, Rubeshan Perumal, Madeleine Hopson

Lancet Microbe· February 2024

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Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance.
Senamile Lale Ngema, Navisha Dookie, Rubeshan Perumal, Louansha Nandlal, Nikita Naicker

J Clin Tuberc Other Mycobact Dis· December 2023

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Baseline and treatment-emergent bedaquiline resistance in drug-resistant tuberculosis: a systematic review and meta-analysis.
Rubeshan Perumal, Neda Bionghi, Camus Nimmo, Marothi Letsoalo, Matthew J Cummings

Eur Respir J· December 2023

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Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Africa (ADAP-TIV): study protocol for an adaptive randomized controlled trial.
Jesse Ross, Rubeshan Perumal, Allison Wolf, Mbali Zulu, Kevin Guzman

Trials· December 2023

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Drug-Resistant TB, HIV and COVID-19 Co-Infection: Case Reviews from Kwa-Zulu Natal, South Africa.
Razia Hassan-Moosa, Kegaugetswe Wilhemina Motsomi, Radhamoney Narasimmulu, Aida Sivro, Kevindra K Naidu, Rubeshan Perumal

Infect Drug Resist· December 2023

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Rapid Diagnosis of Drug-Resistant Tuberculosis-Opportunities and Challenges.
Kogieleum Naidoo, Rubeshan Perumal, Senamile L Ngema, Letitia Shunmugam, Anou M Somboro

Pathogens· December 2023

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Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection.
Emmanuella Chinonso Osuala, Anushka Naidoo, Kelly E Dooley, Kogieleum Naidoo, Rubeshan Perumal

Expert Rev Clin Pharmacol· November 2023

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The hidden epidemic of post-tuberculosis bronchiectasis.
Rubeshan Perumal

Afr J Thorac Crit Care Med· November 2023

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Higher plasma interleukin - 6 levels are associated with lung cavitation in drug-resistant tuberculosis.
Thando Glory Maseko, Slindile Ngubane, Marothi Letsoalo, Santhuri Rambaran, Derseree Archary, Rubeshan Perumal

BMC Immunol· August 2023

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NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity.
Thando Glory Maseko, Santhuri Rambaran, Slindile Ngubane, Lara Lewis, Sinaye Ngcapu, Rubeshan Perumal

Sci Rep· July 2023

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Biological mechanisms underpinning the development of long COVID.
Rubeshan Perumal, Letitia Shunmugam, Kogieleum Naidoo, Dave Wilkins, Alfredo Garzino-Demo

iScience· June 2023

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Metformin Increases Cell Viability and Regulates Pro-Inflammatory Response to Mtb.
Nikita Naicker, Hylton Rodel, Rubeshan Perumal, Yashica Ganga, Mallory Bernstein

Infect Drug Resist· June 2023

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Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Africa (ADAP-TIV): Study protocol for an adaptive randomized controlled trial.
Jesse E Ross, Rubeshan Perumal, Allison Wolf, Mbali Zulu, Kevin Guzman

Res Sq· June 2023

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Long COVID: An approach to clinical assessment and management in primary care.
Rubeshan Perumal, Letitia Shunmugam, Kogieleum Naidoo

S Afr Fam Pract (2004)· June 2023

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