Publications by authors named "Ruby Chan"

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Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Gai Ayalon, Seung-Hye Lee, Oskar Adolfsson, Corinne Foo-Atkins, Jasvinder K Atwal, Ruby Chan, Priya Chandra

Sci Transl Med· May 2021

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High-throughput screening of antibody variants for chemical stability: identification of deamidation-resistant mutants.
Danielle M DiCara, Nisana Andersen, Ruby Chan, James A Ernst, Gai Ayalon

MAbs· October 2018

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Cathelicidin-encoding Lactococcus lactis promotes mucosal repair in murine experimental colitis.
Clover C M Wong, Lin Zhang, William K K Wu, Jing Shen, Ruby L Y Chan

J Gastroenterol Hepatol· March 2017

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Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
Seung-Hye Lee, Claire E Le Pichon, Oskar Adolfsson, Valérie Gafner, Maria Pihlgren, Ruby Chan

Cell Rep· August 2016

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Correction: FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells.
Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Franky L Chan, Francis K L Chan

PLoS One· May 2016

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Miltirone induced mitochondrial dysfunction and ROS-dependent apoptosis in colon cancer cells.
Lin Wang, Tao Hu, Jing Shen, Lin Zhang, Long-Fei Li, Ruby Lok-Yi Chan

Life Sci· April 2016

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Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21.
Diana Ronai Dunshee, Travis W Bainbridge, Noelyn M Kljavin, Jose Zavala-Solorio, Amy C Schroeder, Ruby Chan

J Biol Chem· March 2016

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Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection.
Lin Zhang, William K K Wu, Richard L Gallo, Evandro F Fang, Wei Hu, Ruby L Y Chan, Kam M Chan, Francis K L Chan, Matthew T V Chan

J Immunol· February 2016

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Dihydrotanshinone I induced apoptosis and autophagy through caspase dependent pathway in colon cancer.
Lin Wang, Tao Hu, Jing Shen, Lin Zhang, Ruby Lok-Yi Chan

Phytomedicine· November 2015

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Vascular-targeted TNFα improves tumor blood vessel function and enhances antitumor immunity and chemotherapy in colorectal cancer.
Lan Lu, Zhi Jie Li, Long Fei Li, William Ka Kei Wu, Jing Shen, Ruby Lok Yi Chan, Kam Ming Chan

J Control Release· July 2015

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Deteriorating effect on bone metabolism and microstructure by passive cigarette smoking through dual actions on osteoblast and osteoclast.
Chun Hay Ko, Ruby Lok Yi Chan, Wing Sum Siu, Wai Ting Shum, Ping Chung Leung

Calcif Tissue Int· May 2015

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Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity.
Tao Hu, Lin Wang, Lin Zhang, Lan Lu, Jing Shen, Ruby L Y Chan

Phytomedicine· May 2015

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Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis.
Jing Shen, Zhangang Xiao, William K K Wu, Maggie H Wang, Ka F To, Ruby L Y Chan, Matthew T V Chan, Francis K L Chan

Cancer Res· February 2015

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Reversal of P-glycoprotein (P-gp) mediated multidrug resistance in colon cancer cells by cryptotanshinone and dihydrotanshinone of Salvia miltiorrhiza.
Tao Hu, Kenneth K W To, Lin Wang, Lin Zhang, Lan Lu, Ruby L Y Chan

Phytomedicine· September 2014

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Animal models of gastrointestinal inflammation and cancer.
L Lu, Ruby L Y Chan, X M Luo, William K K Wu, Vivian Y Shin

Life Sci· July 2014

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FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.
Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Franky L Chan, Francis K L Chan

PLoS One· December 2013

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Photocycle of the LOV-STAS protein from the pathogen Listeria monocytogenes.
Ruby H Chan, James W Lewis, Roberto A Bogomolni

Photochem Photobiol· November 2013

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miRNAs in gastrointestinal and liver cancers: their perspectives and clinical applications.
Jing Shen, William K K Wu, Shun X Ren, Lin Zhang, Ruby L Y Chan

Curr Pharm Des· August 2013

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Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer.
Shun X Ren, Alfred S L Cheng, Ka F To, Joanna H M Tong, May S Li, Ruby L Y Chan, Francis K L Chan

Cancer Res· December 2012

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Structural water cluster as a possible proton acceptor in the adduct decay reaction of oat phototropin 1 LOV2 domain.
Ruby H Chan, Roberto A Bogomolni

J Phys Chem B· September 2012

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Antibacterial peptides and gastrointestinal diseases.
Clover C M Wong, Lin Zhang, Shun X Ren, Jing Shen, Ruby L Y Chan

Curr Pharm Des· November 2011

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Interferon-gamma and cancer immunoediting.
Gavin P Dunn, Hiroaki Ikeda, Allen T Bruce, Catherine Koebel, Ravi Uppaluri, Ruby Chan

Immunol Res· August 2006

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