Publications by authors named "Ruby Law"

Claim this Profile
M
Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin.
Simon J A Wiedemeyer, Guojie Wu, Heike Lang-Henkel, James C Whisstock, Ruby H P Law

ChemMedChem· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogens.
S Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Maxim Litvak, Tracey Z He, Ruby H P Law

Blood· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteoform-Resolved Profiling of Plasminogen Activation Reveals Novel Abundant Phosphorylation Site and Primary N-Terminal Cleavage Site.
Dario A T Cramer, Victor Yin, Tomislav Caval, Vojtech Franc, Dingyi Yu, Ruby H P Law

Mol Cell Proteomics· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fragment-based and structure-guided discovery of perforin inhibitors.
Jiney Jose, Ruby H P Law, Eleanor W W Leung, Dorothy C C Wai, Hedieh Akhlaghi

Eur J Med Chem· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen.
Adam J Quek, Nathan P Cowieson, Tom T Caradoc-Davies, Paul J Conroy, James C Whisstock, Ruby H P Law

Int J Mol Sci· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.
Jiaul Islam, Paul Conroy, Christian Fercher, Mijin Kim, Zvi Yaari, Ruby Law

ACS Chem Biol· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The role of NINJ1 protein in programmed cellular destruction.
James C Whisstock, Ruby H P Law

Nature· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
Simon J A Wiedemeyer, Guojie Wu, T L Phuong Pham, Heike Lang-Henkel, Benjamin Perez Urzua, Ruby H P Law

ChemMedChem· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Swapping N-terminal regions among tick evasins reveals cooperative interactions influencing chemokine binding and selectivity.
Pramod Aryal, Shankar Raj Devkota, Devadharshini Jeevarajah, Ruby Law, Richard J Payne

J Biol Chem· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains.
Aleksandr Shamanaev, Ivan Ivanov, Mao-Fu Sun, Maxim Litvak, Priyanka Srivastava, Ruby H P Law

Blood Adv· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mechanism for hereditary angioedema caused by a lysine 311-to-glutamic acid substitution in plasminogen.
S Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M Mohammed, Dennis R Phillips, Ruby H P Law

Blood· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma.
Thomas Kryza, Tashbib Khan, Simon Puttick, Chao Li, Kamil A Sokolowski, Ruby H P Law

Theranostics· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.
Brittney S Harrington, Yaowu He, Tashbib Khan, Simon Puttick, Paul J Conroy, Ruby H P Law

Theranostics· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.
Milena M Awad, Melanie L Hutton, Adam J Quek, William P Klare, Steven J Mileto, Ruby H P Law

Gastroenterology· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.
Andrew M White, Simon J de Veer, Guojie Wu, Peta J Harvey, Kuok Yap, Ruby H P Law

Angew Chem Int Ed Engl· July 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
Yue Yuan, Yetunde A Ayinuola, Damini Singh, Olawole Ayinuola, Jeffrey A Mayfield, Ruby H P Law

J Struct Biol· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.
Adam J H Quek, Blake A Mazzitelli, Guojie Wu, Eleanor W W Leung, Tom T Caradoc-Davies, Ruby H P Law

J Mol Biol· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A Spicer, Ruby H P Law

Nat Commun· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural studies of plasmin inhibition.
Guojie Wu, Adam J Quek, Tom T Caradoc-Davies, Sue M Ekkel, Blake Mazzitelli, Ruby H P Law

Biochem Soc Trans· April 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.
Guojie Wu, Blake A Mazzitelli, Adam J Quek, Matthew J Veldman, Paul J Conroy, Ruby H P Law

Blood Adv· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library.
Choi Yi Li, Simon J de Veer, Ruby H P Law, James C Whisstock, David J Craik

Chembiochem· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
Joakim E Swedberg, Guojie Wu, Tunjung Mahatmanto, Thomas Durek, Tom T Caradoc-Davies, Ruby H P Law

J Med Chem· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
Maiada M Sadek, Nicholas Barlow, Eleanor W W Leung, Billy J Williams-Noonan, Beow Keat Yap, Ruby H P Law

ACS Chem Biol· October 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma.
Hsiao P J Voon, Maheshi Udugama, Wendi Lin, Linda Hii, Ruby H P Law

Nat Commun· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Bradley A Spicer, Ruby H P Law, Tom T Caradoc-Davies, Sue M Ekkel, Charles Bayly-Jones

Nat Commun· August 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis