Publications by authors named "Ruby Lieshout"

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Cholangiocarcinoma cell proliferation is enhanced in primary sclerosing cholangitis: A role for IL-17A.
Ruby Lieshout, Eline J C A Kamp, Monique M A Verstegen, Michail Doukas, Winand N M Dinjens

Int J Cancer· June 2023

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Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.
Gilles S van Tienderen, Oskar Rosmark, Ruby Lieshout, Jorke Willemse, Floor de Weijer

Acta Biomater· March 2023

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Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment.
Michael Koch, Sandra Nickel, Ruby Lieshout, Susanna M Lissek, Martina Leskova

Cells· November 2022

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Modelling immune cytotoxicity for cholangiocarcinoma with tumour-derived organoids and effector T cells.
Guoying Zhou, Ruby Lieshout, Gilles S van Tienderen, Valeska de Ruiter, Martin E van Royen

Br J Cancer· September 2022

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Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification.
Ruby Lieshout, Alessandra V S Faria, Maikel P Peppelenbosch, Luc J W van der Laan, Monique M A Verstegen

Mol Med· June 2022

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Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance.
Jiaye Liu, Pengfei Li, Ling Wang, Meng Li, Zhouhong Ge, Ruby Lieshout

Cell Mol Gastroenterol Hepatol· December 2021

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Cholangiocyte organoids from human bile retain a local phenotype and can repopulate bile ducts in vitro.
Floris J M Roos, Haoyu Wu, Jorke Willemse, Ruby Lieshout, Laura A Muñoz Albarinos

Clin Transl Med· December 2021

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Precancerous liver diseases do not cause increased mutagenesis in liver stem cells.
Luan Nguyen, Myrthe Jager, Ruby Lieshout, Petra E de Ruiter, Mauro D Locati

Commun Biol· November 2021

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Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.
Kerstin Schneeberger, Natalia Sánchez-Romero, Shicheng Ye, Frank G van Steenbeek, Loes A Oosterhoff, Ruby Lieshout

Hepatology· July 2020

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Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth.
Meng Li, Ling Wang, Yijin Wang, Shaoshi Zhang, Guoying Zhou, Ruby Lieshout

Cells· January 2020

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Experimental models to unravel the molecular pathogenesis, cell of origin and stem cell properties of cholangiocarcinoma.
Silvestre Vicent, Ruby Lieshout, Anna Saborowski, Monique M A Verstegen, Chiara Raggi

Liver Int· May 2019

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Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Laura Broutier, Gianmarco Mastrogiovanni, Monique Ma Verstegen, Hayley E Francies, Lena Morrill Gavarró, Ruby Lieshout

Nat Med· December 2017

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From organoids to organs: Bioengineering liver grafts from hepatic stem cells and matrix.
Jorke Willemse, Ruby Lieshout, Luc J W van der Laan, Monique M A Verstegen

Best Pract Res Clin Gastroenterol· April 2017

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