Publications by authors named "Ruixue Wan"

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Dynamic U2AF cycling defines two phases of cotranscriptional pre-mRNA splicing.
Changwei Shao, Yajing Hao, Li Jiang, Dong Wang, Rui Wang, Hui Wang, Ruixue Wan

Science· September 2025

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Ginsenoside Rg1 Alleviates Sepsis-Induced Acute Lung Injury by Reducing FBXO3 Stability in an mA-Dependent Manner to Activate PGC-1α/Nrf2 Signaling Pathway.
Rong Liu, Qiang Wang, Yao Li, Ruixue Wan, Ping Yang

AAPS J· April 2024

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Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Rui Bai, Meng Yuan, Pu Zhang, Ting Luo, Yigong Shi, Ruixue Wan

Science· March 2024

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Structure of the activated human minor spliceosome.
Rui Bai, Ruixue Wan, Lin Wang, Kui Xu, Qiangfeng Zhang

Science· March 2021

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Paternal Subclinical Hypothyroidism Affects the Clinical Outcomes of Fertilization/Intracytoplasmic Sperm Injection.
Meng Rao, Zexing Yang, Cunmei Su, Zihan Zhao, Ruixue Wan, Kunhua Wang

Thyroid· January 2021

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Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Rui Bai, Ruixue Wan, Chuangye Yan, Qi Jia, Jianlin Lei

Science· January 2021

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How Is Precursor Messenger RNA Spliced by the Spliceosome?
Ruixue Wan, Rui Bai, Xiechao Zhan, Yigong Shi

Annu Rev Biochem· June 2020

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Molecular choreography of pre-mRNA splicing by the spliceosome.
Ruixue Wan, Rui Bai, Yigong Shi

Curr Opin Struct Biol· December 2019

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Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
Ruixue Wan, Rui Bai, Chuangye Yan, Jianlin Lei, Yigong Shi

Cell· April 2019

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Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome.
Chuangye Yan, Ruixue Wan, Yigong Shi

Cold Spring Harb Perspect Biol· January 2019

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A key component of gene expression, revealed.
Ruixue Wan

Science· November 2018

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Structures of the fully assembled spliceosome before activation.
Rui Bai, Ruixue Wan, Chuangye Yan, Jianlin Lei, Yigong Shi

Science· June 2018

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Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae.
Rui Bai, Chuangye Yan, Ruixue Wan, Jianlin Lei, Yigong Shi

Cell· December 2017

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Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae.
Ruixue Wan, Chuangye Yan, Rui Bai, Jianlin Lei, Yigong Shi

Cell· September 2017

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Structure of a yeast step II catalytically activated spliceosome.
Chuangye Yan, Ruixue Wan, Rui Bai, Gaoxingyu Huang, Yigong Shi

Science· January 2017

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Structure of a yeast activated spliceosome at 3.5 Å resolution.
Chuangye Yan, Ruixue Wan, Rui Bai, Gaoxingyu Huang, Yigong Shi

Science· August 2016

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Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution.
Ruixue Wan, Chuangye Yan, Rui Bai, Gaoxingyu Huang, Yigong Shi

Science· August 2016

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The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis.
Ruixue Wan, Chuangye Yan, Rui Bai, Lin Wang, Min Huang

Science· January 2016

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Structural basis of pre-mRNA splicing.
Jing Hang, Ruixue Wan, Chuangye Yan, Yigong Shi

Science· September 2015

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Structure of a yeast spliceosome at 3.6-angstrom resolution.
Chuangye Yan, Jing Hang, Ruixue Wan, Min Huang, Catherine C L Wong

Science· September 2015

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Crystal structure and biochemical analysis of the heptameric Lsm1-7 complex.
Lijun Zhou, Yulin Zhou, Jing Hang, Ruixue Wan, Guifeng Lu

Cell Res· April 2014

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Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA.
Lijun Zhou, Jing Hang, Yulin Zhou, Ruixue Wan, Guifeng Lu

Nature· February 2014

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