Publications by authors named "Run-Lei Du"

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CLK2 Regulates the KEAP1/NRF2 and p53 Pathways to Suppress Ferroptosis in Colorectal Cancer.
Hai-Meng Zhou, Yi Liu, Feng Shi, Hao-Wen Qiu, Le Li, Run-Lei Du

Cancer Res· December 2025

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USP13 promotes colorectal cancer progression by deubiquitinating and stabilizing HIF-1α.
Bo Gu, Si-Yu Chang, Ke-Ke Li, Bai-Qi Wang, Shao-Bo Ke, Run-Lei Du

Cell Commun Signal· November 2025

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Ubiquitin-specific protease 13 promotes colorectal cancer progression by stabilizing mitogen-activated protein kinase kinase 3.
Si-Yu Chang, Bo Gu, Yong Xiong, Meng-Si Zhao, Le Li, Run-Lei Du

Mol Biomed· November 2025

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VRK2 promotes colorectal cancer growth and impedes immunotherapy and 5-FU treatment efficacy.
Yu-Tong Wu, Meng Gao, Kun-Yang Cheng, Le Li, Bai-Qi Wang, Run-Lei Du

Biochim Biophys Acta Mol Basis Dis· April 2025

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USP19 deficiency enhances T-cell-mediated antitumor immunity by promoting PD-L1 degradation in colorectal cancer.
Feng Shi, Guang-Jing Li, Yi Liu, Hai-Meng Zhou, Yue Zhang, Run-Lei Du

Pharmacol Res· April 2025

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ANP32E promotes esophageal cancer progression and paclitaxel resistance via P53/SLC7A11 axis-regulated ferroptosis.
Li-Ying Sun, Shao-Bo Ke, Bo-Xin Li, Fei-Shan Chen, Zhi-Qun Huang, Run-Lei Du

Int Immunopharmacol· January 2025

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A Four Amino Acid Metabolism-Associated Genes (AMGs) Signature for Predicting Overall Survival Outcomes and Immunotherapeutic Efficacy in Hepatocellular Carcinoma.
Lu-Sheng Liao, Zi-Jun Xiao, Jun-Li Wang, Ting-Jun Liu, Feng-Die Huang, Run-Lei Du

Biochem Genet· June 2024

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CLK2 mediates IκBα-independent early termination of NF-κB activation by inducing cytoplasmic redistribution and degradation.
Shang-Ze Li, Qi-Peng Shu, Hai-Meng Zhou, Yu-Ying Liu, Meng-Qi Fan, Xue-Hua Du, Run-Lei Du

Nat Commun· May 2024

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Exploring the potential biological function of GRK2 in colorectal cancer.
Meng Gao, Xinyi Liang, Mengqi Fan, Yutong Wu, Ming-You Dong, Run-Lei Du

Funct Integr Genomics· March 2024

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Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Tao Liu, Meng-Qi Fan, Xiao-Xiao Xie, Qi-Peng Shu, Xue-Hua Du, Run-Lei Du

J Transl Med· September 2023

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USP14 promotes colorectal cancer progression by targeting JNK for stabilization.
Xue-Hua Du, Shao-Bo Ke, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Run-Lei Du

Cell Death Dis· January 2023

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A cancer stem cell associated gene signature for predicting overall survival of hepatocellular carcinoma.
Xin-Yi Liang, Yue Zhang, Ya-Nan He, Xue-Yi Liu, Zhi-Hao Ding, Run-Lei Du

Front Genet· September 2022

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c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro.
Rongfu Tu, Wenqian Kang, Ye Kang, Ziyi Chen, Peng Zhang, Run-Lei Du

Biochem Biophys Res Commun· June 2022

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NLK is required for Ras/ERK/SRF/ELK signaling to tune skeletal muscle development by phosphorylating SRF and antagonizing the SRF/MKL pathway.
Shang-Ze Li, Ze-Yan Zhang, Jie Chen, Ming-You Dong, Xue-Hua Du, Run-Lei Du

Cell Death Discov· January 2022

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PTPN18 promotes colorectal cancer progression by regulating the c-MYC-CDK4 axis.
Chao Li, Shang-Ze Li, Xi-Cheng Huang, Jie Chen, Wenbin Liu, Run-Lei Du

Genes Dis· November 2021

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miR-210 Participates in Hepatic Ischemia Reperfusion Injury by Forming a Negative Feedback Loop With SMAD4.
Wen-Ming Pan, Hui Wang, Xiao-Fei Zhang, Peng Xu, Guo-Liang Wang, Run-Lei Du

Hepatology· December 2020

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DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer.
Qi Zhang, Ze-Yan Zhang, Huan Du, Shang-Ze Li, Rongfu Tu, Run-Lei Du

Cell Death Differ· November 2019

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Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.
Shang-Ze Li, Qi-Peng Shu, Yang Song, Hui-Hui Zhang, Yi Liu, Run-Lei Du

Nat Commun· July 2019

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Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling.
Huan Zhao, Wen-Ming Pan, Hui-Hui Zhang, Yang Song, Jie Chen, Run-Lei Du

Cell Death Dis· April 2019

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Cordycepin induces Bax‑dependent apoptosis in colorectal cancer cells.
Shang-Ze Li, Jian-Wei Ren, Jing Fei, Xiao-Dong Zhang, Run-Lei Du

Mol Med Rep· February 2019

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Hypoxia-induced microRNA-191 contributes to hepatic ischemia/reperfusion injury through the ZONAB/Cyclin D1 axis.
Wenming Pan, Lin Wang, Xiao-Fei Zhang, Hongji Zhang, Jinxiang Zhang, Run-Lei Du

Cell Death Differ· January 2019

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Nemo-like kinase (NLK) primes colorectal cancer progression by releasing the E2F1 complex from HDAC1.
Shang-Ze Li, Feng Zeng, Jun Li, Qi-Peng Shu, Hui-Hui Zhang, Run-Lei Du

Cancer Lett· September 2018

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USP49 participates in the DNA damage response by forming a positive feedback loop with p53.
Rongfu Tu, Wenqian Kang, Xuefei Yang, Qi Zhang, Xiaoyu Xie, Run-Lei Du

Cell Death Dis· May 2018

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Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents.
Xiao-Fei Zhang, Rong-Qin Sun, Yi-Fan Jia, Qing Chen, Rong-Fu Tu, Run-Lei Du

Sci Rep· September 2016

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Stabilization of ATF5 by TAK1-Nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway.
Ze-Yan Zhang, Shang-Ze Li, Hui-Hui Zhang, Qu-Ran Wu, Jun Gong, Run-Lei Du

Mol Cell Biol· March 2015

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