Publications by authors named "Rune V Overgaard"

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A model-based approach to predict individual weight loss with semaglutide in people with overweight or obesity.
Anders Strathe, Deborah B Horn, Malte Selch Larsen, Domenica Rubino, Rasmus Sørrig, Rune Viig Overgaard

Diabetes Obes Metab· November 2023

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Clinical Pharmacokinetics of Oral Semaglutide: Analyses of Data from Clinical Pharmacology Trials.
Rune V Overgaard, Andrea Navarria, Steen H Ingwersen, Tine A Bækdal, Rasmus Juul Kildemoes

Clin Pharmacokinet· October 2021

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Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes.
Rune V Overgaard, Christin L Hertz, Steen H Ingwersen, Andrea Navarria, Daniel J Drucker

Cell Rep Med· September 2021

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Optimal Monitoring of Weekly IGF-I Levels During Growth Hormone Therapy With Once-Weekly Somapacitan.
Rasmus Juul Kildemoes, Michael Højby Rasmussen, Henrik Agersø, Rune Viig Overgaard

J Clin Endocrinol Metab· January 2021

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Impact of dose-escalation schemes and drug discontinuation on weight loss outcomes with liraglutide 3.0 mg: A model-based approach.
Theodoros Papathanasiou, Anders Strathe, Henrik Agersø, Trine Meldgaard Lund, Rune Viig Overgaard

Diabetes Obes Metab· June 2020

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Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models.
Theodoros Papathanasiou, Anders Strathe, Rune Viig Overgaard, Trine Meldgaard Lund, Andrew C Hooker

AAPS J· July 2019

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Population Pharmacokinetics of Semaglutide for Type 2 Diabetes.
Rune V Overgaard, Philip H Delff, Kristin C C Petri, Thomas W Anderson, Anne Flint

Diabetes Ther· April 2019

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Pharmacokinetics and Pharmacodynamics of Once-Weekly Somapacitan in Children and Adults: Supporting Dosing Rationales with a Model-Based Analysis of Three Phase I Trials.
Rasmus Vestergaard Juul, Michael Højby Rasmussen, Henrik Agersø, Rune Viig Overgaard

Clin Pharmacokinet· January 2019

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Impact on HbA1c and body weight of switching from other GLP-1 receptor agonists to semaglutide: A model-based approach.
Rune V Overgaard, Søren Ø Lindberg, Desirée Thielke

Diabetes Obes Metab· January 2019

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Exposure-response analysis for evaluation of semaglutide dose levels in type 2 diabetes.
Kristin C C Petri, Steen H Ingwersen, Anne Flint, Jeppe Zacho, Rune V Overgaard

Diabetes Obes Metab· September 2018

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Semaglutide s.c. Once-Weekly in Type 2 Diabetes: A Population Pharmacokinetic Analysis.
Kristin Cecilie Carlsson Petri, Steen Hvass Ingwersen, Anne Flint, Jeppe Zacho, Rune Viig Overgaard

Diabetes Ther· August 2018

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Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations.
Theodoros Papathanasiou, Anders Strathe, Andrew C Hooker, Trine Meldgaard Lund, Rune Viig Overgaard

AAPS J· April 2018

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Anti-NKG2D monoclonal antibody (NNC0142-0002) in active Crohn's disease: a randomised controlled trial.
Matthieu Allez, Brett E Skolnick, Maria Wisniewska-Jarosinska, Robert Petryka, Rune Viig Overgaard

Gut· November 2017

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Liraglutide 3.0 mg for Weight Management: A Population Pharmacokinetic Analysis.
Rune V Overgaard, Kristin C Petri, Lisbeth V Jacobsen, Christine B Jensen

Clin Pharmacokinet· November 2016

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Body composition is the main determinant for the difference in type 2 diabetes pathophysiology between Japanese and Caucasians.
Jonas B Møller, Maria Pedersen, Haruhiko Tanaka, Mitsuru Ohsugi, Rune V Overgaard

Diabetes Care· August 2015

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Clinical pharmacokinetics of the anti-interleukin-20 monoclonal antibody NNC0109-0012 in healthy volunteers and patients with psoriasis or rheumatoid arthritis.
Mia Sandberg Lundblad, Rune Viig Overgaard, Marie Göthberg, Marianne Scheel Fjording, Estelle Watson

Adv Ther· March 2015

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Ethnic differences in insulin sensitivity, β-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis.
Jonas B Møller, Chiara Dalla Man, Rune V Overgaard, Steen H Ingwersen, Christoffer W Tornøe

J Clin Endocrinol Metab· November 2014

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Pharmacokinetics of an anti-TFPI monoclonal antibody (concizumab) blocking the TFPI interaction with the active site of FXa in Cynomolgus monkeys after iv and sc administration.
Henrik Agersø, Rune Viig Overgaard, Mads Bjelke Petersen, Lene Hansen, Mette Brunsgaard Hermit

Eur J Pharm Sci· June 2014

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Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test.
Jonas B Møller, William J Jusko, Wei Gao, Torben Hansen, Oluf Pedersen, Rune V Overgaard

J Pharmacokinet Pharmacodyn· December 2011

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An integrated disease/pharmacokinetic/pharmacodynamic model suggests improved interleukin-21 regimens validated prospectively for mouse solid cancers.
Moran Elishmereni, Yuri Kheifetz, Henrik Søndergaard, Rune Viig Overgaard, Zvia Agur

PLoS Comput Biol· September 2011

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Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test.
Jonas B Møller, Rune V Overgaard, Henrik Madsen, Torben Hansen, Oluf Pedersen

J Pharmacokinet Pharmacodyn· February 2010

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Population stochastic modelling (PSM)--an R package for mixed-effects models based on stochastic differential equations.
Søren Klim, Stig Bousgaard Mortensen, Niels Rode Kristensen, Rune Viig Overgaard, Henrik Madsen

Comput Methods Programs Biomed· June 2009

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A matlab framework for estimation of NLME models using stochastic differential equations: applications for estimation of insulin secretion rates.
Stig B Mortensen, Søren Klim, Bernd Dammann, Niels R Kristensen, Henrik Madsen, Rune V Overgaard

J Pharmacokinet Pharmacodyn· October 2007

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Pharmacodynamic model of interleukin-21 effects on red blood cells in cynomolgus monkeys.
Rune V Overgaard, Mats Karlsson, Steen H Ingwersen

J Pharmacokinet Pharmacodyn· August 2007

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PKPD model of interleukin-21 effects on thermoregulation in monkeys--application and evaluation of stochastic differential equations.
Rune Viig Overgaard, Nick Holford, Klaus A Rytved, Henrik Madsen

Pharm Res· February 2007

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