Publications by authors named "Runxia Gu"

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Clonal architecture of FLT3-ITD and acquired 13q uniparental disomy define prognostic heterogeneity and therapeutic vulnerabilities in acute myeloid leukemia.
Anli Lai, Wenbing Liu, Yihan Mei, Qimin Zhang, Junping Zhang, Runxia Gu

Neoplasia· December 2025

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The critical role of DNA damage-inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Runxia Gu

Mol Oncol· November 2025

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Progression significance for low-level aberrant B-lymphoblasts in chronic myeloid leukaemia patients.
Haoren Wang, Huijun Wang, Yuanyuan Li, Bin Zheng, Qiuyun Fang, Runxia Gu

Clin Transl Med· November 2025

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Single-cell transcriptome profiling reveals blast cell heterogeneity and identifies novel therapeutic target IKZF2 in t(8;21) acute myeloid leukaemia.
Yu Liu, Wenbing Liu, Yihan Mei, Qianqian Huang, Xiaoyu Liu, Chengcai Guo, Runxia Gu

Br J Haematol· October 2025

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Correction: Olverembatinib combined with venetoclax and reduced-intensity chemotherapy for adult newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia: a single-center, single-arm, phase 2 trial.
Xiaoyuan Gong, Wenbing Liu, Yuntao Liu, Qiuyun Fang, Runxia Gu, Guangji Zhang

Leukemia· October 2025

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Clinical features and treatment response to TKIs in chronic myeloid leukemia patients with atypical BCR::ABL1 transcripts.
Haoren Wang, Cong Han, Benfa Gong, Yuntao Liu, Kaiqi Liu, Runxia Gu

Leuk Res· August 2025

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Olverembatinib combined with venetoclax and reduced-intensity chemotherapy for adult newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia: a single-center, single-arm, phase 2 trial.
Xiaoyuan Gong, Wenbing Liu, Yuntao Liu, Qiuyun Fang, Runxia Gu, Guangji Zhang

Leukemia· August 2025

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Novel loop structure of human IgG1 Fc fused CD38 targeted bispecific antibodies and their anti-tumor effect in acute myeloid leukemia.
Shisen Wang, Manling Chen, Tong Zhou, Chengcai Guo, Zhifeng Yan, Runxia Gu

J Transl Med· July 2025

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Prognostic impact of co-mutations in adults with -mutated acute myeloid leukemia.
Anli Lai, Wenbing Liu, Chunlin Zhou, Yan Li, Shuning Wei, Guangji Zhang, Runxia Gu

Blood Sci· June 2025

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AML1-ETO and CCND2 overexpression cooperate to drive acute myeloid leukemia initiation and progression.
Junli Mou, Qianqian Huang, Xiaoyu Liu, Wenbing Liu, Yu Liu, Runxia Gu

J Leukoc Biol· June 2025

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The Clinical and Molecular Characterization of Distinct Subtypes in Adult T Cell Acute Lymphoblastic Leukemia.
Heye Yu, Wenbing Liu, Junping Zhang, Leling Xie, Anli Lai, Runxia Gu

Cancer Sci· April 2025

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Inaticabtagene autoleucel in adult relapsed or refractory B-cell acute lymphoblastic leukemia.
Ying Wang, Lulu Lv, Yongping Song, Xudong Wei, Hongsheng Zhou, Runxia Gu

Blood Adv· February 2025

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U2AF1 mutation causes an oxidative stress and DNA repair defect in hematopoietic and leukemic cells.
Yishuang Li, Xuanjia Dong, Haiyan Xing, Wenbing Liu, Runxia Gu, Guoguang Zheng

Free Radic Biol Med· February 2025

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The dynamic evolution of lineage switch under CD19 CAR-T treatment in non-KMT2A rearranged B-ALL patients.
Shaowei Qiu, Yihan Mei, Runxia Gu, Yu Liu, Manling Chen

Leukemia· January 2025

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Risk stratification in the clinical application of minimal residual disease assessment in acute myeloid leukemia.
Congxiao Zhang, Runxia Gu, Huijun Wang, Chunlin Zhou, Yan Li, Guangji Zhang

Cancer· January 2025

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Targeting Fatty Acid Metabolism Abrogates the Differentiation Blockade in Preleukemic Cells.
Xiaoyu Liu, Yu Liu, Qing Rao, Yihan Mei, Haiyan Xing, Runxia Gu

Cancer Res· December 2024

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Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia.
Haotian Ma, Zhifeng Yan, Runxia Gu, Yingxi Xu, Shaowei Qiu

Cancer Immunol Immunother· November 2024

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A pediatric-inspired regimen for adolescent and adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a prospective study from China.
Xiaoyuan Gong, Qiuyun Fang, Runxia Gu, Shaowei Qiu, Kaiqi Liu, Guangji Zhang

Haematologica· October 2024

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Slow-replicating leukemia cells represent a leukemia stem cell population with high cell-surface CD74 expression.
Huan Li, Zhijie Cao, Yiming Liu, Zhenya Xue, Yishuang Li, Runxia Gu

Mol Oncol· October 2024

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A dual-targeting approach with anti-IL10R CAR-T cells engineered to release anti-CD33 bispecific antibody in enhancing killing effect on acute myeloid leukemia cells.
Zhifeng Yan, Runxia Gu, Haotian Ma, Nianci Chen, Ting Zhang

Cell Oncol (Dordr)· October 2024

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Identifying ADGRG1 as a specific marker for tumor-reactive T cells in acute myeloid leukemia.
Yihan Mei, Yu Liu, Wenbing Liu, Manling Chen, Xiaoyu Liu, Runxia Gu

Exp Hematol Oncol· September 2024

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Multiomic analysis identifies a high-risk subgroup that predicts poor prognosis in t(8;21) acute myeloid leukemia.
Yu Liu, Wenbing Liu, Anli Lai, Yihan Mei, Ying Wang, Runxia Gu

Blood Cancer J· September 2024

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Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Tianxiang Zhang, Weiwei Yu, Xiaoxiao Cheng, Jacky Yeung, Viviana Ahumada, Runxia Gu, Miguel F Sanmamed

Sci Immunol· April 2024

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The RTK-RAS signaling pathway is enriched in patients with rare acute myeloid leukemia harboring t(16;21)(p11;q22)/.
Anli Lai, Wenbing Liu, Hui Wei, Ying Wang, Dong Lin, Runxia Gu, Guangji Zhang

Blood Sci· April 2024

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Universal Anti-CD7 CAR-T Cells Targeting T-ALL and Functional Analysis of CD7 Antigen on T/CAR-T Cells.
Leling Xie, Runxia Gu, Xue Yang, Shaowei Qiu, Yingxi Xu

Hum Gene Ther· December 2023

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