Publications by authors named "Ruobing Ren"

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A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential.
Ting Liu, Ji-Hao Zhou, Yongbo Gong, Ying Zhang, Yongcan Ma, Ruobing Ren

Cell Rep· November 2025

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α-Ketoglutarate dictates AMPK protein synthesis for energy sensing in human cancers.
Wen Mi, Yun Xue, Haohang Yan, Yurou Zhang, Xinlei Cai, Ruobing Ren

Nat Chem Biol· August 2025

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Fine structural design of 3βHSD1 inhibitors for prostate cancer therapy.
Dongyin He, Luyao Zhang, Leiye Yu, Yuhang Zhang, Jingjing Chen, Ruobing Ren

Proc Natl Acad Sci U S A· July 2025

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The Fungal Secretory Peptide Micasin Induces Itch by Activating MRGPRX1/C11/A1 on Peripheral Neurons.
Haifeng Yang, Yian Chen, Luyao Wang, Bing Gan, Leiye Yu, Ruobing Ren

J Invest Dermatol· March 2025

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ACSS2 drives senescence-associated secretory phenotype by limiting purine biosynthesis through PAICS acetylation.
Li Yang, Jianwei You, Xincheng Yang, Ruishu Jiao, Jie Xu, Ruobing Ren

Nat Commun· February 2025

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Molecular insights into the inhibition of proton-activated chloride channel by transfer RNA.
Pengliang Chi, Xiang Wang, Jialu Li, Hui Yang, Kaiju Li, Ruobing Ren

Cell Res· October 2024

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Pipette-tip solid-phase extraction coupled with matrix-assisted laser desorption/ionization mass spectrometry enables rapid and high-throughput analysis of antidepressants in rat serum.
Zhi Sun, Fangfang Wang, Wenxuan Li, Ruobing Ren, Peipei Zhou

Anal Bioanal Chem· September 2024

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Multiomics profiling of the therapeutic effect of Dan-deng-tong-nao capsule on cerebral ischemia-reperfusion injury.
Yingying Shi, Qiuzheng Du, Zhuolun Li, Lianping Xue, Qingquan Jia, Ruobing Ren

Phytomedicine· June 2024

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Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2.
Shiyu Liang, Aijun Liu, Yezhou Liu, Fuxing Wang, Youli Zhou, Ruobing Ren

Proc Natl Acad Sci U S A· June 2024

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Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Haizhan Jiao, Bin Pang, Aijun Liu, Qiang Chen, Qi Pan, Ruobing Ren

Nat Struct Mol Biol· April 2024

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The 3-hydroxyacyl-CoA dehydratase 1/2 form complex with trans-2-enoyl-CoA reductase involved in substrates transfer in very long chain fatty acid elongation.
Youli Zhou, Rui Lv, Richard D Ye, Ruobing Ren, Leiye Yu

Biochem Biophys Res Commun· April 2024

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Identifying Residues for Substrate Recognition in Human GPAT4 by Molecular Dynamics Simulations.
Yulan Liu, Yunong Xu, Yinuo Xu, Zhihao Zhao, Gui-Juan Cheng, Ruobing Ren

Int J Mol Sci· March 2024

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Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport.
Bin Pang, Leiye Yu, Tong Li, Haizhan Jiao, Xiaomei Wu, Ruobing Ren

Cell Res· February 2024

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Fine-tuning activation specificity of G-protein-coupled receptors via automated path searching.
Rujuan Ti, Bin Pang, Leiye Yu, Bing Gan, Wenzhuo Ma, Ruobing Ren

Proc Natl Acad Sci U S A· February 2024

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Active DHEA uptake in the prostate gland correlates with aggressive prostate cancer.
Xuebin Zhang, Zengming Wang, Shengsong Huang, Dongyin He, Weiwei Yan, Ruobing Ren

J Clin Invest· December 2023

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Approach1es for evolutionary, biochemical, and structural analysis of bacterial steroid 5α-reductases.
Yufei Han, Qian Zhuang, Ruobing Ren

Methods Enzymol· November 2023

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Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487.
Haizhan Jiao, Bin Pang, Ying-Chih Chiang, Qiang Chen, Qi Pan, Ruobing Ren

Cell Discov· November 2023

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An LC-MS-based workflow measures the export activity of S1P transporters.
Xiaomei Wu, Bin Pang, Jianwei You, Leiye Yu, Ruobing Ren

Biochem Biophys Res Commun· August 2023

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Mechanism of agonist-induced activation of the human itch receptor MRGPRX1.
Bing Gan, Leiye Yu, Haifeng Yang, Haizhan Jiao, Bin Pang, Ruobing Ren

PLoS Biol· June 2023

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Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Chen Wang, Leiye Yu, Jiying Zhang, Yanxia Zhou, Bo Sun, Ruobing Ren

Nat Commun· March 2023

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Exploring the Chemical Space of CYP17A1 Inhibitors Using Cheminformatics and Machine Learning.
Tianshi Yu, Tianyang Huang, Leiye Yu, Chanin Nantasenamat, Nuttapat Anuwongcharoen, Ruobing Ren

Molecules· February 2023

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Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Qihang Zhong, Honglei Chu, Guopeng Wang, Cheng Zhang, Rong Li, Ruobing Ren

Cell Discov· December 2022

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Prior knowledge facilitates low homologous protein secondary structure prediction with DSM distillation.
Qin Wang, Jun Wei, Yuzhe Zhou, Mingzhi Lin, Ruobing Ren

Bioinformatics· July 2022

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Structural insights into sphingosine-1-phosphate receptor activation.
Leiye Yu, Licong He, Bing Gan, Rujuan Ti, Qingjie Xiao, Ruobing Ren

Proc Natl Acad Sci U S A· April 2022

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Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer.
Zemin Hou, Shengsong Huang, Zejie Mei, Longlong Chen, Jiacheng Guo, Ruobing Ren

Cell Rep Med· March 2022

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