Publications by authors named "Rupert P Austin"

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Erratum to "Survival of the Fittest: Time-To-Event Modelling of Crystallisation of Amorphous Poorly Soluble Drugs".
Katarzyna Nurzyńska, Rupert P Austin, Peter M Fischer, Jonathan Booth, Frank Gommer

J Pharm Sci· November 2016

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Survival of the Fittest: Time-To-Event Modeling of Crystallization of Amorphous Poorly Soluble Drugs.
Katarzyna Nurzyńska, Rupert P Austin, Peter M Fischer, Jonathan Booth, Frank Gommer

J Pharm Sci· June 2016

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Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists.
Rupert P Austin, Colin Bennion, Roger V Bonnert, Lal Cheema, Anthony R Cook

Bioorg Med Chem Lett· April 2015

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The effect of ionized species on microsomal binding.
Michael H Abraham, Rupert P Austin

Eur J Med Chem· January 2012

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A highly automated assay for determining the aqueous equilibrium solubility of drug discovery compounds.
Mark C Wenlock, Rupert P Austin, Tim Potter, Patrick Barton

J Lab Autom· August 2011

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A kinetic method for the determination of plasma protein binding of compounds unstable in plasma: Specific application to enalapril.
Mark C Wenlock, Patrick Barton, Rupert P Austin

J Pharm Biomed Anal· June 2011

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A method for measuring the lipophilicity of compounds in mixtures of 10.
Mark C Wenlock, Tim Potter, Patrick Barton, Rupert P Austin

J Biomol Screen· March 2011

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The thermodynamics of the partitioning of ionizing molecules between aqueous buffers and phospholipid membranes.
Rupert P Austin, Patrick Barton, Andrew M Davis, Roger E Fessey, Mark C Wenlock

Pharm Res· October 2005

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The binding of drugs to hepatocytes and its relationship to physicochemical properties.
Rupert P Austin, Patrick Barton, Sarfraz Mohmed, Robert J Riley

Drug Metab Dispos· March 2005

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QSAR and the rational design of long-acting dual D2-receptor/beta 2-adrenoceptor agonists.
Rupert P Austin, Patrick Barton, Roger V Bonnert, Roger C Brown, Peter A Cage

J Med Chem· July 2003

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A comparison of physiochemical property profiles of development and marketed oral drugs.
Mark C Wenlock, Rupert P Austin, Patrick Barton, Andrew M Davis, Paul D Leeson

J Med Chem· March 2003

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Structure-reactivity relationships in the inactivation of elastase by beta-sultams.
Paul S Hinchliffe, J Matthew Wood, Andrew M Davis, Rupert P Austin, R Paul Beckett

Org Biomol Chem· January 2003

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The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties.
Rupert P Austin, Patrick Barton, Scott L Cockroft, Mark C Wenlock, Robert J Riley

Drug Metab Dispos· December 2002

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Hydrolysis of a sulfonamide by a novel elimination mechanism generated by carbanion formation in the leaving group.
J Matthew Wood, Paul S Hinchliffe, Andy M Davis, Rupert P Austin, Michael I Page

Chem Commun (Camb)· April 2002

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