Publications by authors named "Russell Dahl"

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A Positive Allosteric Modulator of the SERCA Pump Rescues Hippocampal Neuronal Circuits Dysfunction and Cognitive Defects in a Mouse Model of Alzheimer's Disease.
Evgenii Gerasimov, Anastasiya Rakovskaya, Ekaterina Pchitskaya, Olga Vlasova, Russell Dahl

J Neurosci· July 2025

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Failed Metabolic Adaptation to Stress Underlies Pathogenesis in a Heterozygous Genetic Disorder.
Robert Harmon, Erin McCarthy, Annette Krol, Jonas Braun, Aashutosh Shetti, Russell Dahl

bioRxiv· April 2025

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SERCA pump as a novel therapeutic target for treating neurodegenerative disorders.
Russell Dahl, Ilya Bezprozvanny

Biochem Biophys Res Commun· November 2024

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Positive Allosteric Modulators of SERCA Pump Restore Dendritic Spines and Rescue Long-Term Potentiation Defects in Alzheimer's Disease Mouse Model.
Anastasiya Rakovskaya, Alexander Erofeev, Egor Vinokurov, Ekaterina Pchitskaya, Russell Dahl

Int J Mol Sci· September 2023

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Positive Allosteric Modulator of SERCA Pump NDC-1173 Exerts Beneficial Effects in Mouse Model of Alzheimer's Disease.
Russell Dahl, Amanda C Moore, Caitlynn Knight, Colleen Mauger, Hua Zhang

Int J Mol Sci· July 2023

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A new target for Alzheimer's disease: A small molecule SERCA activator is neuroprotective in vitro and improves memory and cognition in APP/PS1 mice.
Katherine Krajnak, Russell Dahl

Bioorg Med Chem Lett· May 2018

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Small molecule SUMOylation activators are novel neuroprotective agents.
Katherine Krajnak, Russell Dahl

Bioorg Med Chem Lett· February 2018

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Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Anthony B Pinkerton, Eduard Sergienko, Yalda Bravo, Russell Dahl, Chen-Ting Ma

Bioorg Med Chem Lett· January 2018

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A new target for Parkinson's disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats.
Russell Dahl

Bioorg Med Chem· January 2017

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Cytoprotective small molecule modulators of endoplasmic reticulum stress.
Soumyabrata Munshi, Russell Dahl

Bioorg Med Chem· June 2016

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Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
Soojeong Kang, Russell Dahl, Wilson Hsieh, Andrew Shin, Krisztina M Zsebo

J Biol Chem· March 2016

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Alamar blue reagent interacts with cell-culture media giving different fluorescence over time: potential for false positives.
Soumyabrata Munshi, Robert C Twining, Russell Dahl

J Pharmacol Toxicol Methods· June 2015

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Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure.
Changwon Kho, Ahyoung Lee, Dongtak Jeong, Jae Gyun Oh, Przemek A Gorski, Russell Dahl

Nat Commun· June 2015

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Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.
Lucia Musumeci, Marijke J Kuijpers, Karen Gilio, Alexandre Hego, Emilie Théâtre, Russell Dahl

Circulation· February 2015

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Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
Yalda Bravo, Peter Teriete, Raveendra-Panickar Dhanya, Russell Dahl, Pooi San Lee

Bioorg Med Chem Lett· September 2014

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Design, synthesis and bioevaluation of an EphA2 receptor-based targeted delivery system.
Elisa Barile, Si Wang, Swadesh K Das, Roberta Noberini, Russell Dahl

ChemMedChem· July 2014

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Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence.
Raveendra-Panickar Dhanya, Douglas J Sheffler, Russell Dahl, Melinda Davis, Pooi San Lee

J Med Chem· May 2014

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Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes.
Robert J Ardecky, Ekaterina V Bobkova, Tina Kiffer-Moreira, Brock Brown, Santhi Ganji, Russell Dahl

Bioorg Med Chem Lett· February 2014

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Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.
Simon J Gruber, Razvan L Cornea, Ji Li, Kurt C Peterson, Tory M Schaaf, Russell Dahl

J Biomol Screen· February 2014

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Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification.
Tina Kiffer-Moreira, Manisha C Yadav, Dongxing Zhu, Sonoko Narisawa, Campbell Sheen, Russell Dahl

J Bone Miner Res· January 2013

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High-throughput FRET assay yields allosteric SERCA activators.
Razvan L Cornea, Simon J Gruber, Elizabeth L Lockamy, Joseph M Muretta, Dongzhu Jin, Russell Dahl

J Biomol Screen· January 2013

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Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.
Shyama Sidique, Raveendra-Panickar Dhanya, Douglas J Sheffler, Hilary Highfield Nickols, Li Yang, Russell Dahl

J Med Chem· November 2012

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