Publications by authors named "Ruth A Kelly"

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Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment.
Nicholas Tolman, Taibo Li, Revathi Balasubramanian, Guorong Li, Rebecca Pfeiffer, Ruth A Kelly

bioRxiv· August 2025

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Endothelial cell-specific postnatal deletion of Nos3 preserves intraocular pressure homeostasis via macrophage recruitment and NOS2 upregulation.
Ruth A Kelly, Megan S Kuhn, Ester Reina-Torres, Revathi Balasubramanian, Kristin M Perkumas

J Clin Invest· February 2025

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Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis.
Katy C Liu, Aleksander O Grimsrud, Maria Fernanda Suarez, Darren Schuman, Michael L De Ieso, Ruth A Kelly

bioRxiv· January 2025

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Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches.
Ted S Acott, Michael P Fautsch, Weiming Mao, C Ross Ethier, Alex S Huang, Ruth A Kelly

Invest Ophthalmol Vis Sci· December 2024

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Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.
Revathi Balasubramanian, Krishnakumar Kizhatil, Taibo Li, Nicholas Tolman, Aakriti Bhandari, Ruth A Kelly

Elife· October 2024

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Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.
Revathi Balasubramanian, Krishnakumar Kizhatil, Taibo Li, Nicholas Tolman, Aakriti Bhandari, Ruth A Kelly

bioRxiv· August 2024

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The Factors Affecting the Stability of IOP Homeostasis.
Darryl R Overby, C Ross Ethier, Changxu Miao, Ruth A Kelly, Ester Reina-Torres

Invest Ophthalmol Vis Sci· June 2024

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Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.
Haiyan Li, Megan Kuhn, Ruth A Kelly, Ayushi Singh, Kavipriya Kovai Palanivel

Am J Physiol Cell Physiol· February 2024

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Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm's canal cell pathobiology.
Haiyan Li, Megan Kuhn, Ruth A Kelly, Ayushi Singh, Kavipriya Kovai Palanivel

bioRxiv· September 2023

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Pressure Clamping During Ocular Perfusions Drives Nitric Oxide-Mediated Washout.
Ruth A Kelly, Fiona S McDonnell, Michael L De Ieso, Darryl R Overby, W Daniel Stamer

Invest Ophthalmol Vis Sci· June 2023

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Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.
Colleen M McDowell, Krishnakumar Kizhatil, Michael H Elliott, Darryl R Overby, Joseph van Batenburg-Sherwood, Ruth A Kelly

Invest Ophthalmol Vis Sci· February 2022

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Fibrotic Changes to Schlemm's Canal Endothelial Cells in Glaucoma.
Ruth A Kelly, Kristin M Perkumas, Matthew Campbell, G Jane Farrar, W Daniel Stamer

Int J Mol Sci· August 2021

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siRNA targeting Schlemm's canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model.
Paul S Cassidy, Ruth A Kelly, Ester Reina-Torres, Joseph M Sherwood, Marian M Humphries

Mol Ther Methods Clin Dev· March 2021

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