Publications by authors named "Ruth Barrientos"

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The aged amygdala's unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis.
Michael J Butler, Jade A Blackwell, Andrew A Sanchez, Hannah F Sanders, Dominic W Kolonay, Ruth M Barrientos

Brain Behav Immun· December 2025

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Neuroinflammatory mechanisms linking high-fat diets to Alzheimer's disease vulnerability: Beyond the amyloid hypothesis.
Sabrina E Mackey-Alfonso, Ruth M Barrientos

Alzheimers Dement· November 2025

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Dr. Steven F. Maier: A fearless scientist, a rigorous mentor, and a legacy of excellence.
Ruth M Barrientos, Michael V Baratta, Matthew G Frank

Brain Behav Immun· August 2025

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AI-based decoding of long covid cognitive impairments in mice using automated behavioral system and comparative transcriptomic analysis.
Heba M Amer, Mohamed M Shamseldin, Sarah Faber, Mostafa Eltobgy, Amy Webb, Ruth M Barrientos

bioRxiv· May 2025

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Ligature-induced periodontitis in a transgenic mouse model of Alzheimer's disease dysregulates neuroinflammation, exacerbates cognitive impairment, and accelerates amyloid pathology.
Daniela M Jimenez-Harrison, Michael J Butler, Haanya Ijaz, Rami Alsabbagh, Menaz N Bettes, Ruth M Barrientos

Brain Behav Immun Health· March 2025

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Obesity-associated memory impairment and neuroinflammation precede widespread peripheral perturbations in aged rats.
Michael J Butler, Stephanie M Muscat, Maria Elisa Caetano-Silva, Akriti Shrestha, Brigitte M González Olmo, Ruth M Barrientos

Immun Ageing· January 2025

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Short-term high fat diet impairs memory, exacerbates the neuroimmune response, and evokes synaptic degradation via a complement-dependent mechanism in a mouse model of Alzheimer's disease.
Sabrina E Mackey-Alfonso, Michael J Butler, Ashton M Taylor, Alberto R Williams-Medina, Stephanie M Muscat, Ruth M Barrientos

Brain Behav Immun· October 2024

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High-fat diet and aging-associated memory impairments persist in the absence of microglia in female rats.
Sajida Malik, Soniya Xavier, Alita Soch, Simin Younesi, Jackson Yip, Ruth M Barrientos

Neurobiol Aging· August 2024

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Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease.
Asmaa Badr, Kylene P Daily, Mostafa Eltobgy, Shady Estfanous, Michelle H Tan, Ruth M Barrientos

Brain Behav Immun· July 2024

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Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementation.
Stephanie M Muscat, Michael J Butler, Menaz N Bettes, James W DeMarsh, Emmanuel A Scaria, Ruth M Barrientos

Brain Behav Immun· February 2024

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Corrigendum to "CD8 T cells contribute to diet-induced memory deficits in aged male rats" [Brain Behav. Immun. 109 (2023) 235-250].
Michael J Butler, Shouvonik Sengupta, Stephanie Muscat, Stephanie A Amici, Rebecca G Biltz, Ruth M Barrientos

Brain Behav Immun· October 2023

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A Comprehensive Study on the Chemical Characterization and Neuroprotective Evaluation of Pracaxi Nuts Extracts Obtained by a Sustainable Approach.
Pouya Mohammadnezhad, Alberto Valdés, Ruth E Barrientos, Elena Ibáñez, Jane Mara Block

Foods· October 2023

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Dietary fatty acids differentially impact phagocytosis, inflammatory gene expression, and mitochondrial respiration in microglial and neuronal cell models.
Michael J Butler, Sabrina E Mackey-Alfonso, Nashali Massa, Kedryn K Baskin, Ruth M Barrientos

Front Cell Neurosci· August 2023

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Chemical Fingerprinting, Aorta Endothelium Relaxation Effect, and Enzymatic Inhibition of Canelo ( J. R. Forst. & G. Forst, (D.C) A. Gray, Family Winteraceae) Fruits.
Ruth E Barrientos, Javier Romero-Parra, Fredi Cifuentes, Javier Palacios, Néstor Jaime Romero-Jola

Foods· July 2023

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Short-term high-fat diet consumption impairs synaptic plasticity in the aged hippocampus via IL-1 signaling.
Brigitte M González Olmo, Menaz N Bettes, James W DeMarsh, Fangli Zhao, Candice Askwith, Ruth M Barrientos

NPJ Sci Food· July 2023

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Young adult and aged female rats are vulnerable to amygdala-dependent, but not hippocampus-dependent, memory impairment following short-term high-fat diet.
Stephanie M Muscat, Michael J Butler, Sabrina E Mackey-Alfonso, Ruth M Barrientos

Brain Res Bull· April 2023

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CD8 T cells contribute to diet-induced memory deficits in aged male rats.
Michael J Butler, Shouvonik Sengupta, Stephanie M Muscat, Stephanie A Amici, Rebecca G Biltz, Ruth M Barrientos

Brain Behav Immun· March 2023

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UHPLC-MS Phenolic Fingerprinting, Aorta Endothelium Relaxation Effect, Antioxidant, and Enzyme Inhibition Activities of Berries.
Lucia Cuesta Ramos, Javier Palacios, Ruth E Barrientos, Jessica Gómez, Juan Manuel Castagnini

Foods· February 2023

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Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats.
Stephanie M Muscat, Nicholas P Deems, Michael J Butler, Emmanuel A Scaria, Menaz N Bettes, Ruth M Barrientos

J Neurosci· January 2023

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Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Phil.
Ruth E Barrientos, Elena Ibáñez, Adrián Puerta, José M Padrón, Adrián Paredes

Antioxidants (Basel)· November 2022

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Phenolic Profile, Antioxidant and Enzyme Inhibition Properties of the Chilean Endemic Plant (Gay) Meissner (Thymelaeaceae).
Carmen Cortés, Diego A González-Cabrera, Ruth Barrientos, Claudio Parra, Javier Romero-Parra

Metabolites· January 2022

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Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation.
Shady Estfanous, Kylene P Daily, Mostafa Eltobgy, Nicholas P Deems, Midhun N K Anne, Ruth M Barrientos

Front Immunol· December 2021

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Dietary DHA prevents cognitive impairment and inflammatory gene expression in aged male rats fed a diet enriched with refined carbohydrates.
Michael J Butler, Nicholas P Deems, Stephanie Muscat, Christopher M Butt, Martha A Belury, Ruth M Barrientos

Brain Behav Immun· November 2021

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The Perfect Cytokine Storm: How Peripheral Immune Challenges Impact Brain Plasticity & Memory Function in Aging.
Stephanie M Muscat, Ruth M Barrientos

Brain Plast· August 2021

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Evolution of the Human Diet and Its Impact on Gut Microbiota, Immune Responses, and Brain Health.
Brigitte M González Olmo, Michael J Butler, Ruth M Barrientos

Nutrients· January 2021

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