Publications by authors named "Ruth Cruz-Cosme"

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Zika virus infection in neonatal mice disrupts connexin 43 and induces cardiac inflammation, implicating viral myocarditis in neonatal pathogenesis.
Shuxuan Li, Wangheng Hou, Najealicka Armstrong, Huan Zhao, Ruth Cruz-Cosme

J Virol· September 2025

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Computational and Experimental Identification of Potential Neutralizing Peptides Derived from Human ACE2 Against SARS-CoV-2 Infection.
Qiaobin Yao, Vidhyanand Mahase, Wangheng Hou, Ruth Cruz-Cosme, Qiyi Tang

bioRxiv· September 2025

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Genetic Conservation and Diversity of SARS-CoV-2 Envelope Gene Across Variants of Concern.
Benjamin M Liu, Qiaobin Yao, Ruth Cruz-Cosme, Casey Yarbrough, Kyah Draper

J Med Virol· January 2025

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SARS-CoV-2 ORF3a induces COVID-19-associated kidney injury through HMGB1-mediated cytokine production.
Chenyu Zhang, Volodymyr Gerzanich, Ruth Cruz-Cosme, Jiantao Zhang, Orest Tsymbalyuk

mBio· November 2024

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Structure-guided mutagenesis targeting interactions between pp150 tegument protein and small capsid protein identify five lethal and two live-attenuated HCMV mutants.
Alexander Stevens, Ruth Cruz-Cosme, Najealicka Armstrong, Qiyi Tang, Z Hong Zhou

Virology· August 2024

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Identification and characterization of Varicella Zoster Virus circular RNA in lytic infection.
Shaomin Yang, Di Cao, Dabbu Kumar Jaijyan, Mei Wang, Jian Liu, Ruth Cruz-Cosme

Nat Commun· June 2024

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Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identify Five Lethal and Two Live Attenuated HCMV Mutants.
Alex Stevens, Ruth Cruz-Cosme, Najealicka Armstrong, Qiyi Tang, Z Hong Zhou

bioRxiv· April 2024

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2-Bromopalmitate depletes lipid droplets to inhibit viral replication.
Dongxiao Liu, Ruth Cruz-Cosme, Yong Wu, Julian Leibowitz, Qiyi Tang

J Virol· April 2024

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Lipid Droplets: Formation, Degradation, and Their Role in Cellular Responses to Flavivirus Infections.
James Z Hsia, Dongxiao Liu, LaPrecious Haynes, Ruth Cruz-Cosme, Qiyi Tang

Microorganisms· March 2024

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Endoplasmic reticulum-associated SARS-CoV-2 ORF3a elicits heightened cytopathic effects despite robust ER-associated degradation.
Jiantao Zhang, Ruth Cruz-Cosme, Chenyu Zhang, Dongxiao Liu, Qiyi Tang

mBio· January 2024

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Insights into the Transcriptome of Human Cytomegalovirus: A Comprehensive Review.
Janine Zeng, Di Cao, Shaomin Yang, Dabbu Kumar Jaijyan, Xiaolian Liu, Ruth Cruz-Cosme

Viruses· August 2023

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Murine Hepatitis Virus Exoribonuclease nsp14 Is Required for the Biogenesis of Viral Circular RNAs.
Shaomin Yang, Ruth Cruz-Cosme, Di Cao, Hong Zhou, Songbin Wu

Microbiol Spectr· June 2023

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Syncytial and Congregative Effects of Dengue and Zika Viruses on the Cell Line Differ among the Viral Strains.
Dongxiao Liu, Lilian Akello Obwolo, Ruth Cruz-Cosme, Qiyi Tang

Zoonoses· March 2023

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Zika Virus Infection Downregulates Connexin 43, Disrupts the Cardiomyocyte Gap Junctions and Induces Heart Diseases in A129 Mice.
Shuxuan Li, Najealicka Armstrong, Huan Zhao, Ruth Cruz-Cosme, Hongwei Yang

J Virol· November 2022

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A novel diG motif in ORF3a protein of SARS-Cov-2 for intracellular transport.
Ruth Cruz-Cosme, Jiantao Zhang, Dongxiao Liu, Vidhyanand Mahase, Bhargava Teja Sallapalli

Front Cell Dev Biol· November 2022

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SARS-CoV-2, SARS-CoV, and MERS-CoV encode circular RNAs of spliceosome-independent origin.
Shaomin Yang, Hong Zhou, Mingde Liu, Dabbu Jaijyan, Ruth Cruz-Cosme

J Med Virol· July 2022

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New intranasal and injectable gene therapy for healthy life extension.
Dabbu Kumar Jaijyan, Anca Selariu, Ruth Cruz-Cosme, Mingming Tong, Shaomin Yang

Proc Natl Acad Sci U S A· May 2022

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Genome-wide characterization of SARS-CoV-2 cytopathogenic proteins in the search of antiviral targets.
Jiantao Zhang, Qi Li, Ruth S Cruz Cosme, Volodymyr Gerzanich, Qiyi Tang

bioRxiv· December 2021

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Correction: A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins.
Jing Zhang, Ruth Cruz-Cosme, Meng-Wei Zhuang, Dongxiao Liu, Yuan Liu

Signal Transduct Target Ther· May 2021

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Genome-Wide Characterization of SARS-CoV-2 Cytopathogenic Proteins in the Search of Antiviral Targets.
Jiantao Zhang, Qi Li, Ruth S Cruz Cosme, Volodymyr Gerzanich, Qiyi Tang

mBio· February 2021

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Circular RNA profiling reveals abundant and diverse circRNAs of SARS-CoV-2, SARS-CoV and MERS-CoV origin.
Shaomin Yang, Hong Zhou, Ruth Cruz-Cosme, Mingde Liu, Jiayu Xu

bioRxiv· December 2020

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A systemic and molecular study of subcellular localization of SARS-CoV-2 proteins.
Jing Zhang, Ruth Cruz-Cosme, Meng-Wei Zhuang, Dongxiao Liu, Yuan Liu

Signal Transduct Target Ther· November 2020

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One of the Triple Poly(A) Signals in the M112-113 Gene Is Important and Sufficient for Stabilizing the M112-113 mRNA and the Replication of Murine Cytomegalovirus.
Ruth Cruz-Cosme, Najealicka Armstrong, Qiyi Tang

Viruses· August 2020

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Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay.
Shuxuan Li, Huan Zhao, Hongwei Yang, Wangheng Hou, Ruth Cruz-Cosme

ACS Infect Dis· May 2020

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Zika virus increases mind bomb 1 levels, causing degradation of pericentriolar material 1 (PCM1) and dispersion of PCM1-containing granules from the centrosome.
Fayuan Wen, Najealicka Armstrong, Wangheng Hou, Ruth Cruz-Cosme, Lilian Akello Obwolo

J Biol Chem· December 2019

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