Publications by authors named "Ruth Hunegnaw"

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A Single-shot ChAd3 Vaccine Provides Protection from Intramuscular and Aerosol Sudan Virus Exposure.
Anna N Honko, Ruth Hunegnaw, Juan I Moliva, Aurélie Ploquin, Caitlyn N M Dulan

bioRxiv· February 2024

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Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial.
Betty Mwesigwa, Katherine V Houser, Amelia R Hofstetter, Ana M Ortega-Villa, Prossy Naluyima, Ruth Hunegnaw

Lancet Infect Dis· December 2023

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An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge.
Alec W Freyn, Caroline Atyeo, Patricia L Earl, Jeffrey L Americo, Gwo-Yu Chuang, Ruth Hunegnaw

Sci Transl Med· October 2023

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Publisher Correction: Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Mohammad Arif Rahman, Massimiliano Bissa, Isabela Silva de Castro, Sabrina Helmold Hait, James D Stamos, Ruth Hunegnaw

Nat Microbiol· August 2023

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Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Mohammad Arif Rahman, Massimiliano Bissa, Isabela Silva de Castro, Sabrina Helmold Hait, James D Stamos, Ruth Hunegnaw

Nat Microbiol· May 2023

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Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial.
Melinda J Hamer, Katherine V Houser, Amelia R Hofstetter, Ana M Ortega-Villa, Christine Lee, Ruth Hunegnaw

Lancet· January 2023

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A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates.
Ruth Hunegnaw, Anna N Honko, Lingshu Wang, Derick Carr, Tamar Murray

Sci Transl Med· December 2022

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Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs.
Courtney L Finch, Thomas H King, Kendra J Alfson, Katie A Albanese, Julianne N P Smith, Ruth Hunegnaw

Vaccines (Basel)· November 2022

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An introduction to the Marburg virus vaccine consortium, MARVAC.
Robert W Cross, Ira M Longini, Stephan Becker, Karin Bok, David Boucher, Ruth Hunegnaw

PLoS Pathog· October 2022

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T Cells Induced by Vaccination and Following SIV Challenge Support Env-Specific Humoral Immunity in the Rectal-Genital Tract and Circulation of Female Rhesus Macaques.
Sabrina Helmold Hait, Christopher James Hogge, Mohammad Arif Rahman, Ruth Hunegnaw, Zuena Mushtaq

Front Immunol· June 2021

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A Mucosal Adenovirus Prime/Systemic Envelope Boost Vaccine Regimen Elicits Responses in Cervicovaginal and Alveolar Macrophages of Rhesus Macaques Associated With Delayed SIV Acquisition and B Cell Help.
Ruth Hunegnaw, Sabrina Helmold Hait, Gospel Enyindah-Asonye, Mohammad Arif Rahman, Eun-Ju Ko

Front Immunol· May 2021

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Virus Control in Vaccinated Rhesus Macaques Is Associated with Neutralizing and Capturing Antibodies against the SHIV Challenge Virus but Not with V1V2 Vaccine-Induced Anti-V2 Antibodies Alone.
Ann J Hessell, Liuzhe Li, Delphine C Malherbe, Philip Barnette, Shilpi Pandey, Ruth Hunegnaw

J Immunol· March 2021

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Overexpression of CD6 and PD-1 Identifies Dysfunctional CD8 T-Cells During Chronic SIV Infection of Rhesus Macaques.
Gospel Enyindah-Asonye, Anthony Nwankwo, Mohammad Arif Rahman, Ruth Hunegnaw, Christopher Hogge

Front Immunol· November 2020

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A Prime/Boost Vaccine Regimen Alters the Rectal Microbiome and Impacts Immune Responses and Viremia Control Post-Simian Immunodeficiency Virus Infection in Male and Female Rhesus Macaques.
Thomas Musich, Vishal Thovarai, David J Venzon, Venkatramanan Mohanram, Iskra Tuero, Ruth Hunegnaw

J Virol· November 2020

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Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques.
Ruth Hunegnaw, Zuena Mushtaq, Gospel Enyindah-Asonye, Tanya Hoang, Marjorie Robert-Guroff

Front Immunol· October 2020

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A Pathogenic Role for Splenic B1 Cells in SIV Disease Progression in Rhesus Macaques.
Gospel Enyindah-Asonye, Anthony Nwankwo, Christopher Hogge, Mohammad Arif Rahman, Sabrina Helmold Hait, Ruth Hunegnaw

Front Immunol· September 2020

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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes.
Sabrina Helmold Hait, Christopher James Hogge, Mohammad Arif Rahman, Eun-Ju Ko, Ruth Hunegnaw

J Immunol· June 2020

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Mucosal-associated invariant T (MAIT) cells provide B-cell help in vaccinated and subsequently SIV-infected Rhesus Macaques.
Mohammad Arif Rahman, Eun-Ju Ko, Farzana Bhuyan, Gospel Enyindah-Asonye, Ruth Hunegnaw

Sci Rep· June 2020

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Differential Effect of Mucosal NKp44 Innate Lymphoid Cells and Δγ Cells on Simian Immunodeficiency Virus Infection Outcome in Rhesus Macaques.
Mohammad Arif Rahman, Eun-Ju Ko, Gospel Enyindah-Asonye, Sabrina Helmold Hait, Christopher Hogge, Ruth Hunegnaw

J Immunol· November 2019

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Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation.
Ruth Hunegnaw, Marina Vassylyeva, Larisa Dubrovsky, Tatiana Pushkarsky, Dmitri Sviridov

Arterioscler Thromb Vasc Biol· September 2016

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HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.
Lucas Jennelle, Ruth Hunegnaw, Larisa Dubrovsky, Tatiana Pushkarsky, Michael L Fitzgerald

J Biol Chem· October 2014

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The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear.
Daria Jacob, Ruth Hunegnaw, Tatyana A Sabyrzyanova, Tatiana Pushkarsky, Vladimir O Chekhov

Biochem Biophys Res Commun· January 2014

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Nuclear cysteine cathepsin variants in thyroid carcinoma cells.
Sofia Tedelind, Kseniia Poliakova, Amanda Valeta, Ruth Hunegnaw, Eyoel Lemma Yemanaberhan

Biol Chem· August 2010

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