Publications by authors named "Ruth J Loos"

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Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.
Joshua S Weinstock, Sharjeel A Chaudhry, Maria Ioannou, Maria Viskadourou, Paula Reventun, Ruth J Loos

Nat Commun· October 2025

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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning.
Eugenia Mazzaferro, Endrina Mujica, Hanqing Zhang, Anastasia Emmanouilidou, Anne Jenseit, Ruth Jf Loos

Sci Rep· February 2025

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Identification of proteins associated with type 2 diabetes risk in diverse racial and ethnic populations.
Shuai Liu, Jingjing Zhu, Hua Zhong, Chong Wu, Haoran Xue, Ruth J Loos

Diabetologia· December 2024

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The Genetic Determinants and Genomic Consequences of Non-Leukemogenic Somatic Point Mutations.
Joshua S Weinstock, Sharjeel A Chaudhry, Maria Ioannou, Maria Viskadourou, Paula Reventun, Ruth J Loos

medRxiv· August 2024

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Integrating Genetic and Transcriptomic Data to Identify Genes Underlying Obesity Risk Loci.
Hanfei Xu, Shreyash Gupta, Ian Dinsmore, Abbey Kollu, Anne Marie Cawley, Ruth Jf Loos

medRxiv· June 2024

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Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations.
Zach Gerhart-Hines, Ruth Jf Loos

Curr Opin Genet Dev· December 2023

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Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.
Yuxuan Wang, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A Holdcraft, Ruth Jf Loos

Am J Hum Genet· October 2023

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Determinants of mosaic chromosomal alteration fitness.
Yash Pershad, Taralynn Mack, Hannah Poisner, Yasminka A Jakubek, Adrienne M Stilp, Ruth J Loos

medRxiv· October 2023

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Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry.
Fei Chen, Ravi K Madduri, Alex A Rodriguez, Burcu F Darst, Alisha Chou, Ruth J Loos

Eur Urol· July 2023

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Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study.
Yuxuan Wang, Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A Holdcraft, Ruth Jf Loos

medRxiv· June 2023

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Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits.
Heather M Highland, Genevieve L Wojcik, Mariaelisa Graff, Katherine K Nishimura, Chani J Hodonsky, Ruth J Loos

Am J Hum Genet· April 2022

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Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.
Margaret A Taub, Matthew P Conomos, Rebecca Keener, Kruthika R Iyer, Joshua S Weinstock, Ruth Jf Loos

Cell Genom· January 2022

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Addendum: A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications.
Thomas W Winkler, Felix Günther, Simon Höllerer, Martina Zimmermann, Ruth Jf Loos

Nat Commun· July 2018

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The genetics of adiposity.
Ruth Jf Loos

Curr Opin Genet Dev· June 2018

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Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.
Chani Jo Hodonsky, Claudia Schurmann, Ursula M Schick, Jonathan Kocarnik, Ran Tao, Ruth Jf Loos

Am J Hematol· June 2018

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A joint view on genetic variants for adiposity differentiates subtypes with distinct metabolic implications.
Thomas W Winkler, Felix Günther, Simon Höllerer, Martina Zimmermann, Ruth Jf Loos

Nat Commun· May 2018

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Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts.
Aline Jelenkovic, Reijo Sund, Yoshie Yokoyama, Yoon-Mi Hur, Vilhelmina Ullemar, Ruth Jf Loos

Sci Rep· April 2018

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Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system.
Gillian Morven Belbin, Jacqueline Odgis, Elena P Sorokin, Muh-Ching Yee, Sumita Kohli, Ruth Jf Loos

Elife· September 2017

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Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts.
Karri Silventoinen, Aline Jelenkovic, Reijo Sund, Yoshie Yokoyama, Yoon-Mi Hur, Ruth Jf Loos

Am J Clin Nutr· August 2017

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Strategies for Enriching Variant Coverage in Candidate Disease Loci on a Multiethnic Genotyping Array.
Stephanie A Bien, Genevieve L Wojcik, Niha Zubair, Christopher R Gignoux, Alicia R Martin, Ruth J F Loos

PLoS One· July 2017

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Blood pressure in young adulthood and residential greenness in the early-life environment of twins.
Esmée M Bijnens, Tim S Nawrot, Ruth Jf Loos, Marij Gielen, Robert Vlietinck

Environ Health· June 2017

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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.
Louise V Wain, Nick Shrine, María Soler Artigas, A Mesut Erzurumluoglu, Boris Noyvert, Ruth J F Loos

Nat Genet· March 2017

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Rare and low-frequency coding variants alter human adult height.
Eirini Marouli, Mariaelisa Graff, Carolina Medina-Gomez, Ken Sin Lo, Andrew R Wood, Ruth J F Loos

Nature· February 2017

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Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
Thomas R Webb, Jeanette Erdmann, Kathleen E Stirrups, Nathan O Stitziel, Nicholas G D Masca, Ruth J F Loos

J Am Coll Cardiol· February 2017

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Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
Aline Jelenkovic, Yoon-Mi Hur, Reijo Sund, Yoshie Yokoyama, Sisira H Siribaddana, Ruth Jf Loos

Elife· December 2016

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