Publications by authors named "Ruth MacDonald"

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Camizestrant causes reversible pharmacological effects on retinal responses in rats.
Gregory Hamm, Gareth Maglennon, Stuart Purbrick, Lucy Flint, Glen Hawthorne, Ruth Macdonald

Transl Oncol· December 2025

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Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Valentina Fogal, Filippos Michopoulos, Andrew F Jarnuczak, Ghaith M Hamza, Stephanie Harlfinger, Ruth Macdonald

Arch Toxicol· August 2024

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Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics.
Tara J Bowen, Andrew D Southam, Andrew R Hall, Ralf J M Weber, Gavin R Lloyd, Ruth Macdonald

Nat Commun· August 2023

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Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper.
Giuditta Illuzzi, Anna D Staniszewska, Sonja J Gill, Andy Pike, Lisa McWilliams, Ruth Macdonald

Clin Cancer Res· November 2022

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Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment.
Gregory Hamm, Gareth Maglennon, Beth Williamson, Ruth Macdonald, Ann Doherty

Arch Toxicol· February 2022

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Validation and utilisation of a digital version of the survey instrument for natural history, Aetiology and Prevalence of Patellofemoral pain studies (eSNAPPS).
Mohamed Yusuf, Paola Dey, Michael Callaghan, Nicola Relph, Phillip Gichuru, Ruth Macdonald

Phys Ther Sport· July 2021

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Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry.
Nicole Strittmatter, Richard M England, Alan M Race, Daniel Sutton, Jennifer I Moss, Ruth Macdonald

Anal Chem· March 2021

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Development of microdialysis methodology for interstitial insulin measurement in rodents.
Ann E Griffin, Ruth Macdonald, Anton J M Wagenmakers, Janice M Marshall, Simon M Poucher

J Pharmacol Toxicol Methods· July 2017

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Processed foods: contributions to nutrition.
Connie M Weaver, Johanna Dwyer, Victor L Fulgoni, Janet C King, Gilbert A Leveille, Ruth S MacDonald

Am J Clin Nutr· June 2014

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Aggressive prostate cancer is prevented in ERαKO mice and stimulated in ERβKO TRAMP mice.
Anna Slusarz, Glenn A Jackson, J Kevin Day, Nader S Shenouda, Jennifer L Bogener, Ruth S MacDonald

Endocrinology· September 2012

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Influence of dietary phytochemicals and microbiota on colon cancer risk.
Ruth S Macdonald, Kelly Wagner

J Agric Food Chem· July 2012

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Soy protein diet, but not Lactobacillus rhamnosus GG, decreases mucin-1, trefoil factor-3, and tumor necrosis factor-α in colon of dextran sodium sulfate-treated C57BL/6 mice.
Huanyi Jiang, Joseph Przybyszewski, Debjani Mitra, Chad Becker, Byron Brehm-Stecher, Ruth S MacDonald

J Nutr· July 2011

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Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.
Anna Slusarz, Nader S Shenouda, Mary S Sakla, Sara K Drenkhahn, Acharan S Narula, Ruth S MacDonald

Cancer Res· April 2010

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Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women.
Wenyi Qin, Weizhu Zhu, Huidong Shi, John E Hewett, Rachel L Ruhlen, Ruth S MacDonald

Nutr Cancer· June 2009

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Soy protein isolate extruded with high moisture retains high nutritional quality.
Ruth S MacDonald, Joseph Pryzbyszewski, Fu-Hung Hsieh

J Agric Food Chem· May 2009

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Zinc deficiency induces vascular pro-inflammatory parameters associated with NF-kappaB and PPAR signaling.
Huiyun Shen, Elizabeth Oesterling, Arnold Stromberg, Michal Toborek, Ruth MacDonald

J Am Coll Nutr· October 2008

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Effects of diets enriched in omega-3 and omega-6 polyunsaturated fatty acids on offspring sex-ratio and maternal behavior in mice.
Emily D Fountain, Jiude Mao, Jeffrey J Whyte, Kelly E Mueller, Mark R Ellersieck, Ruth Macdonald

Biol Reprod· February 2008

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Zinc deficiency alters lipid metabolism in LDL receptor deficient mice treated with rosiglitazone.
Huiyun Shen, Ruth MacDonald, Dennis Bruemmer, Arnold Stromberg, Alan Daugherty

J Nutr· November 2007

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Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells.
Mary S Sakla, Nader S Shenouda, Pete J Ansell, Ruth S Macdonald, Dennis B Lubahn

Endocrine· August 2007

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Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo.
Nader S Shenouda, Mary S Sakla, Leslie G Newton, Cynthia Besch-Williford, Norman M Greenberg, Ruth S MacDonald

Endocrine· February 2007

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Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits.
Qun Wang, Albert Y Sun, Agnes Simonyi, Michael D Jensen, Phullara B Shelat, Ruth S MacDonald

J Neurosci Res· October 2005

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Zinc deficiency increases plasma lipids and atherosclerotic markers in LDL-receptor-deficient mice.
Gudrun Reiterer, Ruth MacDonald, Jim D Browning, Jason Morrow, Sergey V Matveev

J Nutr· September 2005

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Dietary grape supplement ameliorates cerebral ischemia-induced neuronal death in gerbils.
Qun Wang, Agnes Simonyi, Wenlu Li, Bryan A Sisk, Rebecca L Miller, Ruth S Macdonald

Mol Nutr Food Res· May 2005

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Environmental influences on isoflavones and saponins in soybeans and their role in colon cancer.
Ruth S MacDonald, Juyuan Guo, Jonathan Copeland, Jimmy D Browning, David Sleper

J Nutr· May 2005

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Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro.
Nader S Shenouda, Christine Zhou, Jimmy D Browning, Pete J Ansell, Mary S Sakla, Ruth S Macdonald

Nutr Cancer· April 2005

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