Publications by authors named "Ruth Olmer"

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Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease.
Mark-Christian Klassen, Anita Balázs, Janina Zöllner, Nicole Cleve, Laurien Czichon, Ruth Olmer

Stem Cell Res Ther· October 2025

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Characterization of 3D human pulmonary epithelial model morphology and oxygen status under normoxia and hypoxia.
Maura Lynch-Miller, Sandra Lockow, Katrin Dümmer, Timo Henneck, Ruth Olmer

Biochim Biophys Acta Mol Cell Res· August 2025

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Structure and function relationships of mucociliary clearance in human and rat airways.
Doris Roth, Ayşe Tuğçe Şahin, Feng Ling, Niels Tepho, Christiana N Senger, Ruth Olmer

Nat Commun· March 2025

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Structure and Function Relationships of Mucociliary Clearance in Human and Rat Airways.
Doris Roth, Ayşe Tuğçe Şahin, Feng Ling, Niels Tepho, Christiana N Senger, Ruth Olmer

bioRxiv· February 2025

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Alpha-1-antitrypsin improves anastomotic healing in intestinal epithelial cells model.
Nagoud Schukfeh, Kokilavani Sivaraman, Aileen Schmidt, Gertrud Vieten, Jens Dingemann, Ruth Olmer

Pediatr Surg Int· September 2024

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STRUCTURE-FUNCTION RELATIONSHIPS OF MUCOCILIARY CLEARANCE IN HUMAN AIRWAYS.
Doris Roth, Ayşe Tuğçe Şahin, Feng Ling, Christiana N Senger, Erik J Quiroz, Ruth Olmer

Res Sq· April 2024

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Ciliary Ultrastructure Assessed by Transmission Electron Microscopy in Adults with Bronchiectasis and Suspected Primary Ciliary Dyskinesia but Inconclusive Genotype.
Ben O Staar, Jan Hegermann, Bernd Auber, Raphael Ewen, Sandra von Hardenberg, Ruth Olmer

Cells· November 2023

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Human pluripotent stem cell fate trajectories toward lung and hepatocyte progenitors.
Chaido Ori, Meshal Ansari, Ilias Angelidis, Ruth Olmer, Ulrich Martin

iScience· November 2023

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Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection.
Baxolele Mhlekude, Dylan Postmus, Saskia Stenzel, January Weiner, Jenny Jansen, Ruth Olmer

PLoS Pathog· September 2023

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NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner.
Fakhar H Waqas, Mahmoud Shehata, Walid A M Elgaher, Antoine Lacour, Naziia Kurmasheva, Ruth Olmer

PLoS Pathog· July 2023

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Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing.
Sylvia Merkert, Alexandra Haase, Julia Dahlmann, Gudrun Göhring, Fakhar H Waqas, Ruth Olmer

Stem Cell Res· June 2023

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Primary Ciliary Dyskinesia Patient-Specific hiPSC-Derived Airway Epithelium in Air-Liquid Interface Culture Recapitulates Disease Specific Phenotypes In Vitro.
Laura von Schledorn, David Puertollano Martín, Nicole Cleve, Janina Zöllner, Doris Roth, Ruth Olmer

Cells· May 2023

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Omicron-induced interferon signaling prevents influenza A H1N1 and H5N1 virus infection.
Denisa Bojkova, Marco Bechtel, Tamara Rothenburger, Joshua D Kandler, Lauren Hayes, Ruth Olmer

J Med Virol· March 2023

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Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform.
Denisa Bojkova, Philipp Reus, Leona Panosch, Marco Bechtel, Tamara Rothenburger, Ruth Olmer

iScience· February 2023

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SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression.
Daniela Niemeyer, Saskia Stenzel, Talitha Veith, Simon Schroeder, Kirstin Friedmann, Ruth Olmer

PLoS Biol· November 2022

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Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line.
Mark-Christian Jaboreck, Jonathan Lukas Lühmann, Mia Mielenz, Frauke Stanke, Gudrun Göhring, Ruth Olmer

Stem Cell Res· October 2022

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Flow-induced glycocalyx formation and cell alignment of HUVECs compared to iPSC-derived ECs for tissue engineering applications.
Marcus Lindner, Anna Laporte, Laura Elomaa, Cornelia Lee-Thedieck, Ruth Olmer

Front Cell Dev Biol· September 2022

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ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives.
Syed Fakhar-Ul-Hassnain Waqas, Aaqib Sohail, Ariane Hai Ha Nguyen, Abdulai Usman, Tobias Ludwig, Ruth Olmer

Clin Transl Med· July 2022

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Congenital deficiency reveals critical role of ISG15 in skin homeostasis.
Muhammad Nasir Hayat Malik, Syed Fakhar-Ul-Hassnain Waqas, Jana Zeitvogel, Jingyuan Cheng, Robert Geffers, Ruth Olmer

J Clin Invest· February 2022

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Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy.
Denisa Bojkova, Rui Costa, Philipp Reus, Marco Bechtel, Mark-Christian Jaboreck, Ruth Olmer

Metabolites· October 2021

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Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in exon 11 of the BMPR2 gene.
Abdulai Usman, Alexandra Haase, Sylvia Merkert, Gudrun Göhring, Georg Hansmann, Ruth Olmer

Stem Cell Res· August 2021

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Towards Biohybrid Lung: Induced Pluripotent Stem Cell Derived Endothelial Cells as Clinically Relevant Cell Source for Biologization.
Michael Pflaum, Julia Dahlmann, Lena Engels, Hossein Naghilouy-Hidaji, Denise Adam, Ruth Olmer

Micromachines (Basel)· August 2021

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High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling.
Felix Manstein, Kevin Ullmann, Christina Kropp, Caroline Halloin, Wiebke Triebert, Ruth Olmer

Stem Cells Transl Med· July 2021

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Production and cryopreservation of definitive endoderm from human pluripotent stem cells under defined and scalable culture conditions.
Anais Sahabian, Julia Dahlmann, Ulrich Martin, Ruth Olmer

Nat Protoc· March 2021

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Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro.
Monika Szepes, Anna Melchert, Julia Dahlmann, Jan Hegermann, Christopher Werlein, Ruth Olmer

Int J Mol Sci· November 2020

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