Publications by authors named "Ruth S Slack"

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Rb substantially compensates for the double loss of p130 and p107 in adult but not embryonic neural stem cell lineages.
Reem Swaidan, Ahmad Daher, Anthony T Bejjani, Yara E El Atie, Yasmina Chehab, Ruth S Slack

Cell Death Dis· July 2025

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Distinct fingerprints of tRNA-derived small non-coding RNA in animal models of neurodegeneration.
Sharada Baindoor, Hesham A Y Gibriel, Morten T Venø, Junyi Su, Elena Perez Morrissey, Ruth S Slack

Dis Model Mech· November 2024

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The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration.
Mohamed Ariff Iqbal, Maria Bilen, Yubing Liu, Vanessa Jabre, Bensun C Fong, Ruth S Slack

Aging Cell· July 2024

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PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.
Dilan Rasool, Audrey Burban, Ahmad Sharanek, Ariel Madrigal, Jinghua Hu, Ruth S Slack

EMBO Rep· March 2024

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PFTK1 kinase regulates axogenesis during development via RhoA activation.
Yasmilde Rodríguez González, Fatemeh Kamkar, Paymaan Jafar-Nejad, Suzi Wang, Dianbo Qu, Ruth S Slack

BMC Biol· October 2023

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Early postnatal defects in neurogenesis in the 3xTg mouse model of Alzheimer's disease.
Yubing Liu, Maria Bilen, Marie-Michelle McNicoll, Richard A Harris, Bensun C Fong, Ruth S Slack

Cell Death Dis· February 2023

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Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis.
Marissa A Lithopoulos, Xavier Toussay, Shumei Zhong, Liqun Xu, Shamimunisa B Mustafa, Ruth S Slack

J Clin Invest· November 2022

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The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state.
Bensun C Fong, Imane Chakroun, Mohamed Ariff Iqbal, Smitha Paul, Joseph Bastasic, Ruth S Slack

Cell Rep· November 2022

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Direct FACS Isolation of Neural Stem/Progenitor Lineages from the Adult Brain.
Mohamed Ariff Iqbal, Bensun C Fong, Ruth S Slack

Methods Mol Biol· July 2022

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Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition.
Doo Soon Im, Alvin Joselin, Devon Svoboda, Tesuya Takano, Maxime W C Rousseaux, Ruth S Slack

BMC Biol· May 2022

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Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production.
David A Patten, Shawn McGuirk, Ujval Anilkumar, Ghadi Antoun, Karan Gandhi, Ruth S Slack

Biochim Biophys Acta Mol Cell Res· January 2021

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MCL-1 maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions.
Ujval Anilkumar, Mireille Khacho, Alexanne Cuillerier, Richard Harris, David A Patten, Ruth S Slack

Cell Death Dis· May 2020

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Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP.
Wassamon Boonying, Alvin Joselin, En Huang, Dianbo Qu, Farzaneh Safarpour, Ruth S Slack

J Neurochem· August 2019

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The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors.
Tianwen Huang, Yasmilde Rodríguez González, Dianbo Qu, En Huang, Farzaneh Safarpour, Ruth S Slack

J Biol Chem· May 2019

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DJ-1 modulates the unfolded protein response and cell death via upregulation of ATF4 following ER stress.
Jungwoo Yang, Kwang Soo Kim, Grace O Iyirhiaro, Paul C Marcogliese, Steve M Callaghan, Ruth S Slack

Cell Death Dis· February 2019

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Mitochondria as central regulators of neural stem cell fate and cognitive function.
Mireille Khacho, Richard Harris, Ruth S Slack

Nat Rev Neurosci· January 2019

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Comparative analysis of Parkinson's disease-associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons.
Nicolas Giguère, Consiglia Pacelli, Caroline Saumure, Marie-Josée Bourque, Diana Matheoud, Ruth S Slack

J Biol Chem· June 2018

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Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.
Kwang Soo Kim, Paul C Marcogliese, Jungwoo Yang, Steve M Callaghan, Virginia Resende, Ruth S Slack

Proc Natl Acad Sci U S A· May 2018

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Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance.
Mireille Khacho, Ruth S Slack

Antioxid Redox Signal· April 2018

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Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.
Niamh M C Connolly, Pierre Theurey, Vera Adam-Vizi, Nicolas G Bazan, Paolo Bernardi, Ruth S Slack

Cell Death Differ· March 2018

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Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain.
Mireille Khacho, Ruth S Slack

Dev Dyn· January 2018

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Mitochondrial activity in the regulation of stem cell self-renewal and differentiation.
Mireille Khacho, Ruth S Slack

Curr Opin Cell Biol· December 2017

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PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.
En Huang, Dianbo Qu, Tianwen Huang, Nicoletta Rizzi, Wassamon Boonying, Ruth S Slack

Nat Commun· November 2017

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Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons.
Matthew Laaper, Takrima Haque, Ruth S Slack, Arezu Jahani-Asl

J Vis Exp· November 2017

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Cdc25A Is a Critical Mediator of Ischemic Neuronal Death and .
Grace O Iyirhiaro, Doo Soon Im, Wassamon Boonying, Steve M Callaghan, Matthew J During, Ruth S Slack

J Neurosci· July 2017

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