Publications by authors named "Ruut Laitio"

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Grey matter volume reduction and its association with brain-enriched blood biomarkers in out-of-hospital cardiac arrest survivors.
Carita C Hollmén, Victor Vorobyev, Riitta Parkkola, Jussi P Posti, Jani Saunavaara, Ruut Laitio, Timo T Laitio

Sci Rep· November 2025

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Effects of intranasal dexmedetomidine premedication on hemodynamics, oxygenation and bleeding in patients undergoing total knee arthroplasty under spinal anesthesia - a secondary analysis of a prospective, double-blinded, randomized controlled trial (TKADEX).
Suvi-Maria Tiainen, Atte Koskinen, Sanna Mäkelä, Ruut Laitio, Eliisa Löyttyniemi

J Clin Anesth· July 2025

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Premedication with intranasal dexmedetomidine in patients undergoing total knee arthroplasty under spinal anaesthesia (TKADEX)-a prospective, double-blinded, randomised controlled trial.
Suvi-Maria Tiainen, Heta Heinonen, Atte Koskinen, Sanna Mäkelä, Ruut Laitio

BJA Open· March 2025

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Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial.
Carita Hollmén, Riitta Parkkola, Victor Vorobyev, Jani Saunavaara, Ruut Laitio, Timo T Laitio

Neurocrit Care· February 2025

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A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest: A post-hoc study of the randomised Xe-Hypotheca trial.
Aleksi J Nummela, Harry Scheinin, Markus Perola, Anni Joensuu, Ruut Laitio, Timo Laitio

PLoS One· June 2024

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Effect of antiplatelet and anticoagulant medication use on injury severity and mortality in patients with traumatic brain injury treated in the intensive care unit.
Juho Vehviläinen, Jyri J Virta, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Acta Neurochir (Wien)· December 2023

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Incidence and risk factors of posttraumatic hydrocephalus and its association with outcome following intensive care unit treatment for traumatic brain injury: a multicenter observational study.
Matias Lindfors, Juho Vehviläinen, Stepani Bendel, Matti Reinikainen, Ruut Laitio

J Neurosurg· November 2023

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Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial.
Mikael Laaksonen, Jaakko Rinne, Melissa Rahi, Jussi P Posti, Ruut Laitio, Timo Laitio

Trials· June 2023

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Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trial.
Kalle Koskensalo, Sami Virtanen, Jani Saunavaara, Riitta Parkkola, Ruut Laitio, Timo T Laitio

Neuroradiology· February 2023

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Trends in Mortality after Intensive Care of Patients with Aneurysmal Subarachnoid Hemorrhage in Finland in 2003-2019: A Finnish Intensive Care Consortium study.
Jyri J Virta, Markus Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Neurocrit Care· October 2022

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Early thrombocytopenia is associated with an increased risk of mortality in patients with traumatic brain injury treated in the intensive care unit: a Finnish Intensive Care Consortium study.
Kadri Lillemäe, Teemu Luostarinen, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Acta Neurochir (Wien)· October 2022

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External validation of the NeuroImaging Radiological Interpretation System and Helsinki computed tomography score for mortality prediction in patients with traumatic brain injury treated in the intensive care unit: a Finnish intensive care consortium study.
Juho Vehviläinen, Markus Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Acta Neurochir (Wien)· October 2022

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One-year healthcare costs of patients with spontaneous intracerebral hemorrhage treated in the intensive care unit.
Marika Smeds, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Sanna Hoppu, Ruut Laitio

Eur Stroke J· September 2022

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Trends in mortality after intensive care of patients with traumatic brain injury in Finland from 2003 to 2019: a Finnish Intensive Care Consortium study.
Teemu Luostarinen, Juho Vehviläinen, Matias Lindfors, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Acta Neurochir (Wien)· January 2022

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Psychotropic medication use among patients with a traumatic brain injury treated in the intensive care unit: a multi-centre observational study.
Juho Vehviläinen, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ivan Marinkovic, Ruut Laitio

Acta Neurochir (Wien)· October 2021

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Effect of Inhaled Xenon on Cardiac Function in Comatose Survivors of Out-of-Hospital Cardiac Arrest-A Substudy of the Xenon in Combination With Hypothermia After Cardiac Arrest Trial.
Antti Saraste, Haitham Ballo, Olli Arola, Ruut Laitio, Juhani Airaksinen, Timo Laitio

Crit Care Explor· August 2021

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One-year costs of intensive care in pediatric patients with traumatic brain injury.
Era D Mikkonen, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

J Neurosurg Pediatr· January 2021

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Psychotropic Medication After Intensive Care Unit-Treated Pediatric Traumatic Brain Injury.
Era D Mikkonen, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Pediatr Neurol· November 2020

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Posttraumatic epilepsy in intensive care unit-treated pediatric traumatic brain injury patients.
Era D Mikkonen, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

Epilepsia· April 2020

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The Association Between Pressure Ulcer/Injury Development and Short-term Mortality in Critically Ill Patients: A Retrospective Cohort Study.
Maarit H Ahtiala, Riku Kivimäki, Ruut Laitio, Esa T Soppi

Wound Manag Prev· February 2020

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Single-subject analysis of N400 event-related potential component with five different methods.
Roosa E Kallionpää, Henri Pesonen, Annalotta Scheinin, Nils Sandman, Ruut Laitio

Int J Psychophysiol· October 2019

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Validation of prognostic models in intensive care unit-treated pediatric traumatic brain injury patients.
Era D Mikkonen, Markus B Skrifvars, Matti Reinikainen, Stepani Bendel, Ruut Laitio

J Neurosurg Pediatr· September 2019

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Alterations in heart rate variability in patients with peripheral arterial disease requiring surgical revascularization have limited association with postoperative major adverse cardiovascular and cerebrovascular events.
Karri T Utriainen, Juhani K Airaksinen, Olli J Polo, Harry Scheinin, Ruut M Laitio, Timo T Laitio

PLoS One· February 2019

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Association of extracerebral organ failure with 1-year survival and healthcare-associated costs after cardiac arrest: an observational database study.
Pirkka T Pekkarinen, Minna Bäcklund, Ilmar Efendijev, Rahul Raj, Daniel Folger, Ruut Laitio

Crit Care· February 2019

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Therapeutic hypothermia and pressure ulcer risk in critically ill intensive care patients: A retrospective study.
Maarit Ahtiala, Ruut Laitio, Esa Soppi

Intensive Crit Care Nurs· June 2018

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